SKL-2841, a dual antagonist of MCP-1 and MIP-1 beta, prevents bleomycin-induced skin sclerosis in mice

Biomedicine and Pharmacotherapy

Volumn 61, Issue 4, 2007, Pages 222-228

  Kimura, Mizuho ^a   Kawahito, Yutaka ^a   Hamaguchi, Masahide ^a   Nakamura, Takashi ^b   Okamoto, Masayuki ^b   Matsumoto, Yukiharu ^b   Endo, Hirahito ^c   Yamamoto, Aihiro ^a   Ishino, Hidetaka ^a   Wada, Makoto ^a   Omoto, Atsushi ^a   Tsubouchi, Yasunori ^a   Kohno, Masataka ^a   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chemokine antagonist; MCP 1; MIP 1 beta; Scleroderma

Indexed keywords

BLEOMYCIN; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN INHIBITOR; SKL 2841; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CHRONIC DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SCLERODERMA; SKIN INFLAMMATION;

ANIMALS; BLEOMYCIN; CHEMOKINE CCL2; CHEMOTAXIS; DISEASE MODELS, ANIMAL; FEMALE; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED C3H; SCLERODERMA, SYSTEMIC; SKIN; SPLEEN;

EID: 34247572897     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2006.10.002     Document Type: Article

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