Comparative analysis of Hoxa5 allelic series

Genesis (United States)

Volumn 45, Issue 4, 2007, Pages 218-228

  Tabariès, Sébastien ^a   Lemieux, Margot ^a   Aubin, Josée ^a   Jeannotte, Lucie ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Cre loxP FLP frt recombination systems; Hox gene targeting; Hoxa5; Lung anomalies; Skeletal transformations

Indexed keywords

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC VARIABILITY; HOXA5 GENE; LETHALITY; MOUSE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL;

EID: 34247555882     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20292     Document Type: Article

References (40)

1. Aubin J, Chauler P, Ménard D, Jeannotte L. 1999. Loss of Hoxa5 gene function perturbs intestinal maturation. Am J Physiol 277:965-973.
2. Aubin J, Davy A, Soriano P. 2004. In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes Dev 18:1482-1494.
3. Aubin J, Déry U, Lemieux M, Chailler P, Jeannotte L. 2002a. Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Development 129:4075-4087.
4. Aubin J, Jeannotte L. 2001. Implication des gènes Hox dans les processus d'organogenèse chez les mammifères. Médecine/ Sciences 17:54-62.
5. Aubin J, Lemieux M, Moreau J, Lapointe J, Jeannotte L. 2002b. Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle. Dev Biol. 244:96-113.
6. Aubin J, Lemieux M, Tremblay M, Behringer RR, Jeannotte L. 1998. Transcriptional interferences at the Hoxa4/Hoxa5 locus: importance of correct Hoxa5 expression for the proper specification of the axial skeleton. Dev Dyn 212:141-156.
7. Aubin J, Lemieux M, Tremblay M, Bérard J, Jeannotte L. 1997. Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects. Dev Biol 192:432-445.
8. Barrow JR, Capecchi MR. 1996. Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Development 122:3817-3828.
9. Bélanger LF, Roy S, Tremblay M, Brott B, Steff AM, Mourad W, Hugo P, Erikson R, Charron J. 2003. Mek2 is dispensable for mouse growth and development. Mol Cell Biol 23:4778-4787.
10. Bouchard M, Souabni A, Mandler M, Neubuser A, Busslinger M. 2002. Nephric lineage specification by Pax2 and Pax8. Genes Dev 16:2958-2970.
11. Deschamps J, van Nes J. 2005. Developmental regulation of the Hox genes during axial morphogenesis in the mouse. Development 132:2931-2942.
12. Duboule D, Morata G. 1994. Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet 10:358-364.
13. Parley FW, Soriano P, Steffen LS, Dymecki SM. 2000. Widespread recombinase expression using FLPeR (flipper) mice. Genesis 28:106-110.
14. Garcia-Fernandez J. 2005. The genesis and evolution of homeobox gene clusters. Nat Rev Genet 6:881-892.
15. Garin E, Lemieux M, Coulombe Y, Robinson GW, Jeannotte L. 2006. Stromal Hoxa5 function controls the growth and differentiation of mammary alveolar epithelium. Dev Dyn 235:1858-1871.
16. Greer JM, Capecchi MR. 2002. Hoxb8 is required for normal grooming behavior in mice. Neuron 33:23-34.
17. Hayashi S, Lewis P, Pevny L, McMahon AP. 2002. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev 119 (Suppl 1):S97-S101.
18. Hayashi S, Tenzen T, McMahon AP. 2003. Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis 37:51-53.
19. Ioffe E, Liu Y, Bhaumik M, Poirier F, Factor SM, Stanley P. 1995. WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc Natl Acad Sci USA 92:7357-7361.
20. Jaffe L, Jeannotte L, Bikoff EK, Robertson EJ. 1990. Analysis of β2-microglobulin in the developing mouse embryo and placenta. J Immunol 145:3474-3482.
21. Jeannotte L, Lemieux M, Charron J, Poirier F, Robertson EJ. 1993. Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene. Genes Dev 7:2085-2096.
22. Jeannotte L, Ruiz JC, Robertson EJ. 1991. Low level of Hox1.3 gene expression does not preclude the use of promoterless vectors to generate a targeted gene disruption. Mol Cell Biol 11:5578-5585.
23. Joksimovic M, Jeannotte L, Tuggle CK. 2005. Dynamic expression of murine HOXA5 protein in the central nervous system. Gene Expr Patterns 5:792-800.
24. Kinkead R, LeBlanc M, Gulemetova R, Lalancette-Hébert M, Lemieux M, Mandeville I, Jeannotte L. 2004. Respiratory adaptations to lung morphological defects in adult mice lacking Hoxa5 gene function. Pediatr Res 56:553-562.
25. Kmita M, Duboule D. 2003. Organizing axes in time and space: 25 years of colinear tinkering. Science 301:331-333.
26. Krumlauf R. 1994. Hox genes in vertebrate development. Cell 78:191-201.
27. Larochelle C, Tremblay M, Bernier D, Aubin J, Jeannotte L. 1999. Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression. Dev Dyn 214:127-140.
28. Mandeville I, Aubin J, LeBlanc M, Lalancette-Hébert M, Janelle MF, Tremblay GM, Jeannotte L. 2006. Impact of the loss of Hoxa5 function on lung alveogenesis. Am J Pathol 169:1312-1327.
29. Meunier D, Aubin J, Jeannotte L. 2003. Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice. Dev Dyn 227:367-378.
30. Meyers EN, Lewandoski M, Martin GR. 1998. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet 18:136-141.
31. Moreau J, Jeannotte L. 2002. Sequence analysis of a Hoxa4-Hoxa5 intergenic region including shared regulatory elements. DNA Seq 13:203-209.
32. Müller U. 1999. Ten years of gene targeting: Targeted mouse mutants, from vector design to phenotype analysis. Mech Dev 82:3-21.
33. Olson EN, Arnold HH, Rigby PW, Wold BJ. 1996. Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 85:1-4.
34. Ren SY, Angrand PO, Rijli FM. 2002. Targeted insertion results in a rhombomere 2-specific Hoxa2 knockdown and ectopic activation of Hoxal expression. Dev Dyn 225:305-315.
35. Rijli FM, Dollé P, Fraulob V, LeMeur M, Chambon P. 1994. Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression. Dev Dyn 201:366-377.
36. Stein S, Fritsch R, Lemaire L, Kessel M. 1996. Checklist: Vertebrate homeobox genes. Mech Dev 55:91-108.
37. Suemori H, Noguchi S. 2000. Hox C cluster genes are dispensable for overall body plan of mouse embryonic development. Dev Biol 220:333-342.
38. Tabariès S, Lapointe J, Besch T, Carter M, Woollard J, Tuggle CK, Jeannotte L. 2005. Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton. Mol Cell Biol 25:1389-1401.
39. Thomas R, Capecchi MR. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503-512.
40. Watrin F, Wolgemuth DJ. 1993. Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene. Dev Biol 156:136-145.