-
1
-
-
5044244757
-
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
-
Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W. R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev Cell 2004; 7:525-34.
-
(2004)
Dev Cell
, vol.7
, pp. 525-534
-
-
Kazanskaya, O.1
Glinka, A.2
del Barco Barrantes, I.3
Stannek, P.4
Niehrs, C.5
Wu, W.6
-
2
-
-
33751547518
-
Dynamic expression of R-spondin family genes in mouse developmen
-
Nam JS, Turcotte TJ, Yoon JK. Dynamic expression of R-spondin family genes in mouse developmen. Gene Expr Patterns 2007; 7:306-12.
-
(2007)
Gene Expr Patterns
, vol.7
, pp. 306-312
-
-
Nam, J.S.1
Turcotte, T.J.2
Yoon, J.K.3
-
3
-
-
23844455584
-
Mitogenic influence of human R-spondin1 on the intestinal epithelium
-
Kim KA, Kakitani M, Zhao J, Oshima T, Tang T, Binnerts M, Liu Y, Boyle B, Park E, Emtage P, Funk WD, Tomizuka K. Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science 2005; 309:1256-9.
-
(2005)
Science
, vol.309
, pp. 1256-1259
-
-
Kim, K.A.1
Kakitani, M.2
Zhao, J.3
Oshima, T.4
Tang, T.5
Binnerts, M.6
Liu, Y.7
Boyle, B.8
Park, E.9
Emtage, P.10
Funk, W.D.11
Tomizuka, K.12
-
4
-
-
33744964431
-
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
-
Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem 2006; 281:13247-57.
-
(2006)
J Biol Chem
, vol.281
, pp. 13247-13257
-
-
Nam, J.S.1
Turcotte, T.J.2
Smith, P.F.3
Choi, S.4
Yoon, J.K.5
-
5
-
-
1642300426
-
-
Kamata T, Katsube K, Michikawa M, Yamada M, Takada S, Mizusawa H. R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Biochim Biophys Acta 2004; 1676:51-62.
-
Kamata T, Katsube K, Michikawa M, Yamada M, Takada S, Mizusawa H. R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Biochim Biophys Acta 2004; 1676:51-62.
-
-
-
-
6
-
-
33750479526
-
The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
-
Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh MT, Ruschendorf F, Sinclair C, Hopsu-Havu VK, Tidman N, Moss C, Watson R, de Berker D, Wajid M, Christiano AM, Kelsell DP. The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Nat Genet 2006; 38:1245-7.
-
(2006)
Nat Genet
, vol.38
, pp. 1245-1247
-
-
Blaydon, D.C.1
Ishii, Y.2
O'Toole, E.A.3
Unsworth, H.C.4
Teh, M.T.5
Ruschendorf, F.6
Sinclair, C.7
Hopsu-Havu, V.K.8
Tidman, N.9
Moss, C.10
Watson, R.11
de Berker, D.12
Wajid, M.13
Christiano, A.M.14
Kelsell, D.P.15
-
7
-
-
33845187080
-
Mutations in the gene encoding the Wnt-signaling component R-spondin 4 (RSPO4) cause autosomal recessive anonychia
-
Bergmann C, Senderek J, Anhuf D, Thiel CT, Ekici AB, Poblete-Gutierrez P, van Steensel M, Seelow D, Nurnberg G, Schild HH, Nurnberg P, Reis A, Frank J, Zerres K. Mutations in the gene encoding the Wnt-signaling component R-spondin 4 (RSPO4) cause autosomal recessive anonychia. Am J Hum Genet 2006; 79:1105-9.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 1105-1109
-
-
Bergmann, C.1
Senderek, J.2
Anhuf, D.3
Thiel, C.T.4
Ekici, A.B.5
Poblete-Gutierrez, P.6
van Steensel, M.7
Seelow, D.8
Nurnberg, G.9
Schild, H.H.10
Nurnberg, P.11
Reis, A.12
Frank, J.13
Zerres, K.14
-
8
-
-
0029772359
-
The mouse Engrailed-1 gene and ventral limb patterning
-
Loomis CA, Harris E, Michaud J, Wurst W, Hanks M, Joyner AL. The mouse Engrailed-1 gene and ventral limb patterning. Nature 1996; 382:360-3.
-
(1996)
Nature
, vol.382
, pp. 360-363
-
-
Loomis, C.A.1
Harris, E.2
Michaud, J.3
Wurst, W.4
Hanks, M.5
Joyner, A.L.6
-
9
-
-
0142040824
-
Fgf signaling controls the number of phalanges and tip formation in developing digits
-
Sanz-Ezquerro JJ, Tickle C. Fgf signaling controls the number of phalanges and tip formation in developing digits. Curr Biol 2003; 13:1830-6.
-
(2003)
Curr Biol
, vol.13
, pp. 1830-1836
-
-
Sanz-Ezquerro, J.J.1
Tickle, C.2
-
10
-
-
34247484673
-
3 From tip to toe or how to make a digit
-
Sanz Ezquerro J. 3 From tip to toe or how to make a digit. J Anat 2002; 201:417.
-
(2002)
J Anat
, vol.201
, pp. 417
-
-
Sanz Ezquerro, J.1
-
11
-
-
0034014330
-
Alteration of beta-catenin expression in esophageal squamous-cell carcinoma
-
Ninomiya I, Endo Y, Fushida S, Sasagawa T, Miyashita T, Fujimura T, Nishimura G, Tani T, Hashimoto T, Yagi M, Shimizu K, Ohta T, Yonemura Y, Inoue M, Sasaki T, Miwa K. Alteration of beta-catenin expression in esophageal squamous-cell carcinoma. Int J Cancer 2000; 85:757-61.
-
(2000)
Int J Cancer
, vol.85
, pp. 757-761
-
-
Ninomiya, I.1
Endo, Y.2
Fushida, S.3
Sasagawa, T.4
Miyashita, T.5
Fujimura, T.6
Nishimura, G.7
Tani, T.8
Hashimoto, T.9
Yagi, M.10
Shimizu, K.11
Ohta, T.12
Yonemura, Y.13
Inoue, M.14
Sasaki, T.15
Miwa, K.16
-
12
-
-
0032953231
-
A common human skin tumor is caused by activating mutations in beta-catenin
-
Chan EF, Gat U, McNiff JM, Fuchs E. A common human skin tumor is caused by activating mutations in beta-catenin. Nat Genet 1999; 21:410-3.
-
(1999)
Nat Genet
, vol.21
, pp. 410-413
-
-
Chan, E.F.1
Gat, U.2
McNiff, J.M.3
Fuchs, E.4
-
13
-
-
0035939818
-
Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland
-
Michaelson JS, Leder P. Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland. Oncogene 2001; 20:5093-9.
-
(2001)
Oncogene
, vol.20
, pp. 5093-5099
-
-
Michaelson, J.S.1
Leder, P.2
-
14
-
-
0037157837
-
A developmental conundrum: A stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells
-
DasGupta R, Rhee H, Fuchs E. A developmental conundrum: A stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol 2002; 158:331-44.
-
(2002)
J Cell Biol
, vol.158
, pp. 331-344
-
-
DasGupta, R.1
Rhee, H.2
Fuchs, E.3
-
15
-
-
33749065765
-
Tcf3 governs stem cell features and represses cell fate determination in skin
-
Nguyen H, Rendl M, Fuchs E. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 2006; 127:171-83.
-
(2006)
Cell
, vol.127
, pp. 171-183
-
-
Nguyen, H.1
Rendl, M.2
Fuchs, E.3
-
16
-
-
0029167307
-
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
-
Zhou P, Byrne C, Jacobs J, Fuchs E. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 1995; 9:700-13.
-
(1995)
Genes Dev
, vol.9
, pp. 700-713
-
-
Zhou, P.1
Byrne, C.2
Jacobs, J.3
Fuchs, E.4
-
17
-
-
0032567078
-
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
-
Gat U, DasGupta R, Degenstein L, Fuchs E. De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 1998; 95:605-14.
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
18
-
-
0030844141
-
Activation of the transcription factor Gli1 and the Sonic hedgehog signaling pathway in skin tumors
-
Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A. Activation of the transcription factor Gli1 and the Sonic hedgehog signaling pathway in skin tumors. Nature 1997; 389:876-81.
-
(1997)
Nature
, vol.389
, pp. 876-881
-
-
Dahmane, N.1
Lee, J.2
Robins, P.3
Heller, P.4
Ruiz i Altaba, A.5
-
19
-
-
25444510786
-
Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event
-
Teh MT, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM, Philpott MP, Young BD, Kelsell DP. Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event. Cancer Res 2005; 65:8597-603.
-
(2005)
Cancer Res
, vol.65
, pp. 8597-8603
-
-
Teh, M.T.1
Blaydon, D.2
Chaplin, T.3
Foot, N.J.4
Skoulakis, S.5
Raghavan, M.6
Harwood, C.A.7
Proby, C.M.8
Philpott, M.P.9
Young, B.D.10
Kelsell, D.P.11
-
20
-
-
16044363842
-
The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas
-
Gailani MR, Stahle-Backdahl M, Leffell DJ, Glynn M, Zaphiropoulos PG, Pressman C, Unden AB, Dean M, Brash DE, Bale AE, Toftgard R. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat Genet 1996; 14:78-81.
-
(1996)
Nat Genet
, vol.14
, pp. 78-81
-
-
Gailani, M.R.1
Stahle-Backdahl, M.2
Leffell, D.J.3
Glynn, M.4
Zaphiropoulos, P.G.5
Pressman, C.6
Unden, A.B.7
Dean, M.8
Brash, D.E.9
Bale, A.E.10
Toftgard, R.11
-
21
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH, Jr., Scott MP. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996; 272:1668-71.
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
Scott, M.P.11
-
24
-
-
34247491334
-
Gli1 acts through Snail and E-cadherin to promote nuclear signaling by beta-catenin
-
Li X, Deng W, Lobo-Ruppert SM, Ruppert JM. Gli1 acts through Snail and E-cadherin to promote nuclear signaling by beta-catenin. Oncogene 2007.
-
(2007)
Oncogene
-
-
Li, X.1
Deng, W.2
Lobo-Ruppert, S.M.3
Ruppert, J.M.4
-
25
-
-
33750489078
-
R-spondin1 is essential in sex determination, skin differentiation and malignancy
-
Parma P, et al. R-spondin1 is essential in sex determination, skin differentiation and malignancy. Nat Genet 2006; 38:1304-9.
-
(2006)
Nat Genet
, vol.38
, pp. 1304-1309
-
-
Parma, P.1
-
26
-
-
22544463973
-
A new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences
-
Lowther W, Wiley K, Smith GH, Callahan R. A new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences. J Virol 2005; 79:10093-6.
-
(2005)
J Virol
, vol.79
, pp. 10093-10096
-
-
Lowther, W.1
Wiley, K.2
Smith, G.H.3
Callahan, R.4
-
27
-
-
18344395853
-
Missense mutations in GJB2 encoding connexin-26 cause the ectodermal dysplasia keratitis-ichthyosis- deafness syndrome
-
Richard G, Rouan F, Willoughby CE, Brown N, Chung P, Ryynanen M, Jabs EW, Bale SJ, DiGiovanna JJ, Uitto J, Russell L. Missense mutations in GJB2 encoding connexin-26 cause the ectodermal dysplasia keratitis-ichthyosis- deafness syndrome. Am J Hum Genet 2002; 70:1341-8.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1341-1348
-
-
Richard, G.1
Rouan, F.2
Willoughby, C.E.3
Brown, N.4
Chung, P.5
Ryynanen, M.6
Jabs, E.W.7
Bale, S.J.8
DiGiovanna, J.J.9
Uitto, J.10
Russell, L.11
-
28
-
-
0033925644
-
A Gene for an autosomal dominant scleroatrophic syndrome predisposing to skin cancer (Huriez syndrome) maps to chromosome 4q23
-
Lee YA, Stevens HP, Delaporte E, Wahn U, Reis A. A Gene for an autosomal dominant scleroatrophic syndrome predisposing to skin cancer (Huriez syndrome) maps to chromosome 4q23. Am J Hum Genet 2000; 66:326-330.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 326-330
-
-
Lee, Y.A.1
Stevens, H.P.2
Delaporte, E.3
Wahn, U.4
Reis, A.5
-
30
-
-
15844403608
-
Close mapping of focal non-epidemolytic palmoplantar keratoderma (PPK) locus associated with oesophageal cancer (TOC)
-
Kelsell DP, Risk JM, Leigh IM, Stevens HP, Ellis A, Hennies H-C, Reis A, Weissenbach J, Bishop DT, Spurr NK, Field JK. Close mapping of focal non-epidemolytic palmoplantar keratoderma (PPK) locus associated with oesophageal cancer (TOC). Hum Mol Genet 1996; 5:857-860.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 857-860
-
-
Kelsell, D.P.1
Risk, J.M.2
Leigh, I.M.3
Stevens, H.P.4
Ellis, A.5
Hennies, H.-C.6
Reis, A.7
Weissenbach, J.8
Bishop, D.T.9
Spurr, N.K.10
Field, J.K.11
-
31
-
-
0036458830
-
Epidermolysis bullosa and cancer
-
Mallipeddi R. Epidermolysis bullosa and cancer. Clin Exp Dermatol 2002; 27:616-23.
-
(2002)
Clin Exp Dermatol
, vol.27
, pp. 616-623
-
-
Mallipeddi, R.1
-
32
-
-
33645026707
-
Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia
-
Haider AS, Peters SB, Kaporis H, Cardinale I, Fei J, Ott J, Blumenberg M, Bowcock AM, Krueger JG, Carucci JA. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. J Invest Dermatol 2006; 126:869-81.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 869-881
-
-
Haider, A.S.1
Peters, S.B.2
Kaporis, H.3
Cardinale, I.4
Fei, J.5
Ott, J.6
Blumenberg, M.7
Bowcock, A.M.8
Krueger, J.G.9
Carucci, J.A.10
|