Close mapping of the focal non-epidermolytic palmoplantar keratoderma (PPK) locus associated with oesophageal cancer (TOC)

Human Molecular Genetics

Volumn 5, Issue 6, 1996, Pages 857-860

  Kelsell, David P ^a   Risk, Janet M ^b   Leigh, Irene M ^a   Stevens, Howard P ^a   Ellis, Anthony ^c   Hennies, Hans C ^d   Reis, André ^d   Weissenbach, Jean ^e   Bishop, D Timothy ^f   Spurr, Nigel K ^a   Field, John K ^b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c Broadgreen Hospital   (United Kingdom)

^d HUMBOLDT UNIVERSITY   (Germany)

^e GÉNÉTHON   (France)

^f ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RISK; ESOPHAGUS CANCER; FAMILY STUDY; GENE; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GERMANY; HAPLOTYPE; HUMAN; KERATOSIS PALMOPLANTARIS; MAJOR CLINICAL STUDY; ONSET AGE; PRIORITY JOURNAL; UNITED KINGDOM; UNITED STATES;

EID: 15844403608     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/5.6.857     Document Type: Article

References (16)

1. Itin,P.H. (1992) Classification of autosomal dominant palmoplantar keratoderma: past, present, future. Dermatol. 185,163-165.
2. Stevens,H.P, Kelsell,D.P., Bryant,S.P, Spurr,N.K., Weissenbach,J., Marger,D., Marger,R.S. and Leigh,I.M. (1996) Palmoplantar keratoderma and malignancy (palmoplantar keratoderma ectodermal dysplasia type III) in an extensive North American pedigree is linked to the TOCG locus (17q24) and show a characteristic clinical phenotype. With bibliography and proposed updated classification of the palmoplantar keratodermas. Arch. Dermatol. in press.
3. Howell-Evans,W., McConnell,R.B., Clarke,C.A. and Sheppard,P.M. (1958) Carcinoma of the oesophagus with keratosis palmaris et plantaris (tylosis). Quart. J. Med. 28,413-429.
4. Ellis,A., Field,J.K., Reld,E.A., Friedmann,P.S., Fryer,A., Howard,P., Leigh,I.M., Risk,J., Shaw,J.M. and Whittaker,J. (1994) Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family - a review of six generations. Eur. J. Cancer, Oral Oncol. 30B, 102-112.
5. Blanchet-Bardon,C., Nazzaro,V., Chevrant-Breton,J., Espie,M., Kerbrat,P. and Le Marec,B. (1987) Hereditary epidermolytic palmoplantar keratoderma associated with breast and ovarian cancer in a large kindred. Br. J. Dermatol. 117, 363-370.
6. Torchard,D., Blanchet-Bardon,C., Serova,O., Langbein,L., Narod,S., Janin,N., Goguel,A.R, Bernheim,N., Franke,W.W., Lenoir,G.M. and Feunteun,J. (1994) Epidermolytic palmoplantar keratoderma cosegregates with a keratin 9 mutation in a pedigree with breast cancer. Nature Genet. 6,106-110.
7. Bianchi,L., Orlandi,A., Iraci,S., Spagnoli,L. and Nini,G. (1994) Punctate porokeratotic keratoderma: its occurrence with internal neoplasia. Clin. Exp. Dermatol. 19, 139-141.
8. Stevens,H.P., Kelsell,D.P, Leigh,I.M., Ostlere,L.S., MacDermot,K.D. and Rustin,M.J.A. (1996) Punctate palmoplantar keratosis and malignancy in a four generation family, and autosomal dominant cancer syndrome. Br. J. Dermatol. in press.
9. Risk,I.M., Whittaker,J., Fryer,A., Ellis,A., Shaw,J.M., Field,E.A., Friedmann,P.S., Bishop,D.T., Bodmer,J., Leigh,I.M. and Field,J.K. (1994) Tylosis oesophageal cancer mapped. Nature Genet. 8, 319-321.
10. Hennies,H.C, Hagedom,M. and Reis,A. (1995) Palmoplantar keratoderma in association with carcinoma of the esophagus maps to chromosome 17q distal to the keratin gene cluster. Genomics 29, 537-540.
11. Aoki,T., Mori,T., Du,X.O., Nisihira,J., Matsubara,T. and Nakamura,Y. (1994) Allelotype study of esophageal carcinoma. Genes, Chromosomes and Cancer 10, 177-182.
12. Shibagaki,I., Shimada,Y., Wagata,T, Ikenaga,M., Imamura,M. and Ishizaki,K. (1994) Allelotype analysis of esophageal squamous cell carcinoma. Cancer Res. 54, 2996-3000.
13. Field,J.K., Kiaris,H., Risk,J.M., Tsiriyotis,C, Adamson,R., Zoumpourlis,V., Rowly,H., Taylor,K., Whittaker,J., Howard,P., Beirne,J.C., Woolgar,J., Vaughan,E.D., Spandidos,D.A. and Jones,A.S. (1995) Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival. Br. J. Cancer 72, 1180-1188.
14. Ah-See,K.W., Cooke,T.G., Pickford,I.R., Soutar,D. and Balmain,A. (1994) An allelotype of squamous cell carcinoma of the head and neck using microsatellite markers. Cancer Res. 54, 1617-1621.
15. Mori,T, Aoki,T., Matsubara,T., Iida,F., Du,X.O., Nishihira,T, Mori,S. and Nakamura,Y. (1994) Frequent loss of heterozygosity in the region including BRCA1 on chromosome 17q in squamous cell carcinomas of the esophagus. Cancer Res. 54, 1638-1640.
16. Gottleib,M. and Chavko,M. (1987) Silver staining of native and denatured eukaryotic DNA in agarose gels. Anal. Biochem. 165, 33-37.