New pH-sensitive glycopolymers for colon-specific drug delivery

Drug Delivery

Volumn 14, Issue 3, 2007, Pages 147-153

  Mahkam, M ^a  

^a AZARBAIJAN SHAHID MADANI UNIVERSITY   (Iran)

Author keywords

5 ASA; Colon Specific Drug Delivery; Glycopolymer; Hydrogel; pH Sensitive

Indexed keywords

1,6 HEXANDIOL DIACRYLATE; 1,6 HEXANDIOL PROPOXYLATE DIACRYLATE; 6 ACRYLOYLGLUCOSE 1,2,3,4 TETRAACETATE; 6 TRITYL GLUCOSE DEXTRO GLUCOSE 1,2, 3,4 TETRAACETATE; ACRYLIC ACID DERIVATIVE; BETA DEXTRO GLUCOSE 1,2,3,4 TETRAACETATE; FREE RADICAL; GLUCOSE 6 ACRYLATE 1,2,3,4 TETRAACETATE; GLUCOSE DERIVATIVE; MESALAZINE; METHACRYLIC ACID; METHYL CHLORIDE; OLSALAZINE; POLYMER; TRIPHENYLMETHYL CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; COLON; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SPECIFICITY; HYDROGEL; HYDROLYSIS; INFRARED SPECTROSCOPY; INTESTINE FLUID; PH; POLYMERIZATION; PRIORITY JOURNAL; SIMULATION; STOMACH JUICE;

AMINOSALICYLIC ACIDS; AZO COMPOUNDS; CALORIMETRY, DIFFERENTIAL SCANNING; COLON; CROSS-LINKING REAGENTS; DRUG DELIVERY SYSTEMS; FREE RADICALS; HYDROGELS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MESALAMINE; POLYMERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS;

EID: 34247524115     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540601067745     Document Type: Article

References (28)

1. Arakawa, T., and Timasheff, S. N. 1982. Stabilization of protein-structure by sugars. Biochemistry 21:6536.
2. Bell, C. L., and Peppas, N. A. 1995. Analysis of molecular interactions in poly (methacrylic acid-g-ethylene glycol) hydrogels. Adv. Polym. Sci. 122:125.
3. Brohult, S. 1940. Synthesis and characterization of pH-sensitive glycopolymers for oral drug delivery systems. Nova Acta Regiae Soc. Sci. Upsal. Ser. IV 12:7.
4. Byrne, M., Park, K., and Peppas, N. A. 2002. Glucose recognition capabilities of hydroxyethyl methacrylate-based hydrogels containing poly (ethylene glycol) chains. Adv. Drug Deliv. Rev. 54:149.
5. Chourasia, M. K., and Jain, S. K. 2003. Pharmaceutical approaches to colon targeted drugs delivery systems. J. Pharm. Pharma. Sci. 6(1):33-66.
6. Chung, K. T., Flunk, G. E., and Egan, M. 1976. Azo dye reduction by anaerobes. Appl. Environ. Microbiol. 5:558.
7. Dordick, J. S., Linhardt, R. J., and Rethwisch, D. G. 1994. Enzymatic and chemoenzymatic preparation of hydrophilic polymers and gels. Chemtech. 24:33.
8. Jeffrey, P. D. 1974. Polymerization behavior of bovine zinc-insulin at neutral pH. Biochemistry 13:4441.
9. Kim, B., and Peppas, N. A. 2002. Synthesis and characterization of pH-sensitive lycopolymers for oral drug delivery systems. J. Biomater. Sci. Polymer Edn. 13(11):1271-1281.
10. Kopeček, J., Kopečková, P., BrØndsted, H., et al. 1992. Polymers for colon-specific drug delivery. J. Control. Rel. 19:121-130.
11. Krogars, K., Heinamaki, J., and Vesalahti, J. 2000. Extrusion- spheronization of pH-sensitive polymeric matrix pellets for possible colonic drug delivery. Int. J. Pharm. 199:187-194.
12. Lennaerts, V., and Gurny, R. 1990. In Bioadhesive Drug Delivery Systems, 93-104. Boca Raton, FL: CRC Press.
13. Lowman, A. M., Morishita, M., Kajita, M., et al. 1999. Oral delivery of insulin using pH-responsive complexation gels. J. Pharm. Sci. 88:933.
14. Lowman, A. M., and Peppas, N. A. 1999. In Encyclopedia of Controlled Drug Delivery, Vol. 1, ed. Mathiowitz, E., p. 397. New York: Wiley.
15. Mahkam, M. 2005. Using pH-sensitive hydrogels containing cubane as a crosslinking agent for oral delivery of insulin. J. Biomed. Mat. Res. (Appl. Biomat.) 15, 75B(1):108-112.
16. Mahkam, M., and Allahverdipoor, M. 2004. Controlled release of biomolecules from pH-sensitive network polymers prepared by radiation polymerization. J. Drug Targ. 12(3):151-156.
17. Mahkam, M., Allahverdipoor, M., Mohammadi, R., et al. 2006. A designed oral delivery system for insulin. J. Bioact. Comp. Polym. 21:135-148.
18. Mahkam, M., Assadi, M. G., and Zahedifar, R., et al. 2004. Linear type azo-containing polyurethanes for colon specific drug delivery. J. Bioact. Comp. Polym. 19:45-53.
19. Mahkam, M., and Doostie, L. 2005. The relation between swelling properties and cross-linking of hydrogels designed for colon-specific drug delivery. J. Drug Del. 12(6):343-347.
20. Miyata, T., and Nakamae, K. 1997. Polymers with pendent saccharides - "glycopolymers". Trends Polym. Sci. 5:198.
21. Morishita, M., Lowman, A. M., Takayama, K., et al. 2002. Controlled release systems based on complexation polymers. J. Control. Rel. 81:25.
22. Peppas, N. A. 1991. Physiologically responsive gels. J. Bioact. Compat. Polym. 6:241.
23. Peppas, N. A., Bures, P., Leobandung, W., et al. 2000. Hydrogels in pharmaceutical formulations. Eur. J. Pharm. Biopharm. 50:27.
24. Peppas, N. A., Keys, K. B., Torres-Lugo, M., et al. 1999. Poly (ethylene glycol)-containing hydrogels in drug delivery. J. Control. Rel. 62:81.
25. Peppas, N. A., Kim, B. S., Donini, C., et al. 2001. In New Trends in Polymers for Oral and Parenteral Administration: from Design to Receptors, ed. G. Barratt, D. Duchêne, F. Fattal, and J. Y. Legendre, p. 32, Paris: Editions de Santé.
26. Timasheff, S. N. 1992. In Stability of Protein Pharmaceuticals, Part B, p. 265. New York: Plenum Press.
27. Torres-Lugo, M., Record, R., and Peppas, N. A. 2002. Physicochemical behavior and cytotoxic effects of p(methacrylic acid-g-ethylene glycol) nanospheres for oral delivery of proteins. J. Control. Rel. 80: 197.
28. Youan, B. C., Hussain, A., and Nguyen, N. 2003. Evaluation of sucrose esters as alternative surfactant in microencapsulation of proteins by the solvent evaporation method, AAPS PharmSci. 5(2):article 22.