Amygdala function in adolescents with congenital adrenal hyperplasia: A model for the study of early steroid abnormalities

Neuropsychologia

Volumn 45, Issue 9, 2007, Pages 2104-2113

  Ernst, Monique ^a   Maheu, Françoise S ^a   Schroth, Elizabeth ^a   Hardin, Julie ^b   Golan, Liza Green ^b   Cameron, Jennifer ^a   Allen, Rachel ^a   Holzer, Stuart ^b   Nelson, Eric ^a   Pine, Daniel S ^a   Merke, Deborah P ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Affective processing; Androgen; Corticosteroid; Development; fMRI; Stress hormones

Indexed keywords

STEROID;

ADOLESCENT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; CLINICAL ARTICLE; CLINICAL STUDY; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HYPERANDROGENISM; MALE; SCORING SYSTEM; TASK PERFORMANCE;

ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; AMYGDALA; BRAIN MAPPING; CASE-CONTROL STUDIES; CHILD; EMOTIONS; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MODELS, BIOLOGICAL; PHOTIC STIMULATION; REACTION TIME; SEX FACTORS;

EID: 34247485995     PISSN: 00283932     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2007.01.019     Document Type: Article

References (53)

1. Adolphs R. Neural systems for recognizing emotion. Current Opinion in Neurobiology 12 (2002) 169-177
2. Berenbaum S.A. Effects of early androgens on sex-typed activities and interests in adolescents with congenital adrenal hyperplasia. Hormones and Behavior 35 (1999) 102-110
3. Berenbaum S.A., Duck S.C., and Bryk K. Behavioral effects of prenatal versus postnatal androgen excess in children with 21-hydroxylase-deficient congenital adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism 85 (2000) 727-733
4. Berenbaum S.A., and Resnick S.M. Early androgen effects on aggression in children and adults with congenital adrenal hyperplasia. Psychoneuroendocrinology 22 (1997) 505-515
5. Berenbaum S.A., and Snyder E. Early hormonal influences on childhood sex-typed activity and playmate preferences: Implications for the development of sexual orientation. Developmental and Psychology 31 (1995) 31-42
6. Charney D.S. Psychobiological mechanisms of resilience and vulnerability: Implications for successful adaptation to extreme stress. The American Journal of Psychiatry 161 (2004) 195-216
7. Cohen J. Statistical power analysis for the behavioral sciences (1998), Lawrence Erlbaum Associates, Inc., NJ
8. Cohen-Bendahan C.C., van de B.C., and Berenbaum S.A. Prenatal sex hormone effects on child and adult sex-typed behavior: Methods and findings. Neuroscience and Biobehavioral Reviews 29 (2005) 353-384
9. de Kloet E.R., Joels M., and Holsboer F. Stress and the brain: From adaptation to disease. Nature Reviews Neuroscience 6 (2005) 463-475
10. Dittmann R.W., Kappes M.H., Kappes M.E., Borger D., Meyer-Bahlburg H.F., Stegner H., et al. Congenital adrenal hyperplasia. II: Gender-related behavior and attitudes in female salt-wasting and simple-virilizing patients. Psychoneuroendocrinology 15 (1990) 421-434
11. DonCarlos L.L., Garcia-Ovejero D., Sarkey S., Garcia-Segura L.M., and Azcoitia I. Androgen receptor immunoreactivity in forebrain axons and dendrites in the rat. Endocrinology 144 (2003) 3632-3638
12. Ekman P., and Friesen W.V. Pictures of facial affect (1976), Consulting Psychologists Press, Palo Alto, CA
13. Frederikse M.E., Lu A., Aylward E., Barta P., and Pearlson G. Sex differences in the inferior parietal lobule. Cerebral Cortex 9 (1999) 896-901
14. Friston K.J., Mechelli A., Turner R., and Price C.J. Nonlinear responses in fMRI: The Balloon model, Volterra kernels, and other hemodynamics. Neuroimage 12 (2000) 466-477
15. Goldstein J.M., Seidman L.J., Horton N.J., Makris N., Kennedy D.N., Caviness Jr. V.S., et al. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cerebral Cortex 11 (2001) 490-497
16. Gron G., Wunderlich A.P., Spitzer M., Tomczak R., and Riepe M.W. Brain activation during human navigation: Gender-different neural networks as substrate of performance. Nature Neuroscience 3 (2000) 404-408
17. Hall C.M., Jones J.A., Meyer-Bahlburg H.F., Dolezal C., Coleman M., Foster P., et al. Behavioral and physical masculinization are related to genotype in girls with congenital adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism 89 (2004) 419-424
18. Hampson E., Rovet J.F., and Altmann D. Spatial reasoning in children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Developmental Neuropsychology 14 (1998) 299-320
19. Hariri A.R., Tessitore A., Mattay V.S., Fera F., and Weinberger D.R. The amygdala response to emotional stimuli: A comparison of faces and scenes. Neuroimage 17 (2002) 317-323
20. Hines M. Sex steroids and human behavior: Prenatal androgen exposure and sex-typical play behavior in children. Annals of the New York Academy of Sciences 1007 (2003) 272-282
21. Hines M., Fane B.A., Pasterski V.L., Mathews G.A., Conway G.S., and Brook C. Spatial abilities following prenatal androgen abnormality: Targeting and mental rotations performance in individuals with congenital adrenal hyperplasia. Psychoneuroendocrinology 28 (2003) 1010-1026
22. Johannsen T.H., Ripa C.P., Reinisch J.M., Schwartz M., Mortensen E.L., and Main K.M. Impaired cognitive function in women with congenital adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism 91 (2006) 1376-1381
23. Kanwisher N., McDermott J., and Chun M.M. The fusiform face area: A module in human extrastriate cortex specialized for face perception. Journal of Neuroscience 17 (1997) 4302-4311
24. Kaufman J., Birmaher B., Brent D., Rao U., Flynn C., Moreci P., et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry 36 (1997) 980-988
25. LeDoux J.E. Emotion circuits in the brain. Annual Review of Neuroscience 23 (2000) 155-184
26. Makino S., Gold P.W., and Schulkin J. Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus. Brain Research 640 (1994) 105-112
27. McClure E.B., Monk C.S., Nelson E.E., Zarahn E., Leibenluft E., Bilder R.M., et al. A developmental examination of gender differences in brain engagement during evaluation of threat. Biological Psychiatry 55 (2004) 1047-1055
28. Merke D.P., and Bornstein S.R. Congenital adrenal hyperplasia. Lancet 365 (2005) 2125-2136
29. Merke D.P., Bornstein S.R., Avila N.A., and Chrousos G.P. NIH conference. Future directions in the study and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Annals of Internal Medicine 136 (2002) 320-334
30. Merke D.P., Fields J.D., Keil M.F., Vaituzis A.C., Chrousos G.P., and Giedd J.N. Children with classic congenital adrenal hyperplasia have decreased amygdala volume: Potential prenatal and postnatal hormonal effects. Journal of Clinical Endocrinology and Metabolism 88 (2003) 1760-1765
31. Meyer-Bahlburg H.F. Gender and sexuality in classic congenital adrenal hyperplasia. Endocrinology and Metabolism Clinics of North America 30 (2001) 155-171
32. Meyer-Bahlburg H.F., Dolezal C., Baker S.W., Carlson A.D., Obeid J.S., and New M.I. Prenatal androgenization affects gender-related behavior but not gender identity in 5-12-year-old girls with congenital adrenal hyperplasia. Archives of Sexual Behavior 33 (2004) 97-104
33. Monk C.S., McClure E.B., Nelson E.E., Zarahn E., Bilder R.M., Leibenluft E., et al. Adolescent immaturity in attention-related brain engagement to emotional facial expressions. Neuroimage 20 (2003) 420-428
34. Morris J.S., Friston K.J., Buchel C., Frith C.D., Young A.W., Calder A.J., et al. A neuromodulatory role for the human amygdala in processing emotional facial expressions. Brain 121 (1998) 47-57
35. Naghdi N., and Asadollahi A. Genomic and nongenomic effects of intrahippocampal microinjection of testosterone on long-term memory in male adult rats. Behavioural Brain Research 153 (2004) 1-6
36. Nass R., and Baker S. Androgen effects on cognition: Congenital adrenal hyperplasia. Psychoneuroendocrinology 16 (1991) 189-201
37. Negri-Cesi P., Colciago A., Celotti F., and Motta M. Sexual differentiation of the brain: Role of testosterone and its active metabolites. Journal of Endocrinological Investigation 27 (2004) 120-127
38. Nelson E.E., McClure E.B., Monk C.S., Zarahn E., Leibenluft E., Pine D.S., et al. Developmental differences in neuronal engagement during implicit encoding of emotional faces: An event-related fMRI study. Journal of Child Psychology and Psychiatry 44 (2003) 1015-1024
39. Pessoa L., McKenna M., Gutierrez E., and Ungerleider L.G. Neural processing of emotional faces requires attention. Proceedings of the National Academy of Sciences of the Unites States of America 99 (2002) 11458-11463
40. Pine D.S., Cohen P., Gurley D., Brook J., and Ma Y. The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. Archives of General Psychiatry 55 (1998) 56-64
41. Rowe R., Maughan B., Worthman C.M., Costello E.J., and Angold A. Testosterone, antisocial behavior, and social dominance in boys: Pubertal development and biosocial interaction. Biological Psychiatry 55 (2004) 546-552
42. Sabatinelli D., Bradley M.M., Fitzsimmons J.R., and Lang P.J. Parallel amygdala and inferotemporal activation reflect emotional intensity and fear relevance. Neuroimage 24 (2005) 1265-1270
43. Servin A., Nordenstrom A., Larsson A., and Bohlin G. Prenatal androgens and gender-typed behavior: A study of girls with mild and severe forms of congenital adrenal hyperplasia. Developmental Psychology 39 (2003) 440-450
44. Szeszko P.R., Robinson D., Alvir J.M., Bilder R.M., Lencz T., Ashtari M., et al. Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder. Archives of General Psychiatry 56 (1999) 913-919
45. Szeszko P.R., Strous R.D., Goldman R.S., Ashtari M., Knuth K.H., Lieberman J.A., et al. Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia. American Journal of Psychiatry 159 (2002) 217-226
46. Taylor S.F., Liberzon I., and Koeppe R.A. The effect of graded aversive stimuli on limbic and visual activation. Neuropsychologia 38 (2000) 1415-1425
47. Vazquez-Pereyra F., Rivas-Arancibia S., Loaeza-Del Castillo A., and Schneider-Rivas S. Modulation of short term and long term memory by steroid sexual hormones. Life Sciences 56 (1995) L255-L260
48. Winston J.S., Strange B.A., O'Doherty J., and Dolan R.J. Automatic and intentional brain responses during evaluation of trustworthiness of faces. Nature Neuroscience 5 (2002) 277-283
49. Wolf O.T., Kuhlmann S., Buss C., Hellhammer D.H., and Kirschbaum C. Cortisol and memory retrieval in humans: Influence of emotional valence. Annals of the New York Academy of Sciences 1032 (2004) 195-197
50. Wood R.I. Thinking about networks in the control of male hamster sexual behavior. Hormones and Behavior 32 (1997) 40-45
51. Worsley K.M., Marrett S., Neelin P., Vandal A.C., Friston K.J., and Evans A.C. A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping 4 (1996) 58-73
52. Zarahn E., Aguirre G.K., and D'Esposito M. Empirical analyses of BOLD fMRI statistics. I. Spatially unsmoothed data collected under null-hypothesis conditions. Neuroimage 5 (1997) 179-197
53. Zitzmann M., and Nieschlag E. Testosterone levels in healthy men and the relation to behavioural and physical characteristics: Facts and constructs. European Journal of Endocrinology 144 (2001) 183-197