Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor

American Journal of Physiology - Cell Physiology

Volumn 292, Issue 4, 2007, Pages

  Tu, Victoria C ^a,b   Sun, Haipeng ^a   Bowden, G Tim ^a   Chen, Qin M ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Avon Products Inc   (United States)

Author keywords

Activator protein 1; Antioxidants; Cardiomyocytes; Hypertrophy; Nuclear factor of activated T cells 3

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANGIOTENSIN II; ANTIOXIDANT; CATALASE; HYDROGEN PEROXIDE; LY 249002; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N TERT BUTYL ALPHA PHENYLNITRONE; THIOCTIC ACID; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG ACTIVITY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSCRIPTION INITIATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCYSTEINE; ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; CATALASE; CELL ENLARGEMENT; CELLS, CULTURED; CYCLIC N-OXIDES; ENZYME ACTIVATION; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; OXIDANTS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; THIOCTIC ACID; TRANSCRIPTION FACTOR AP-1;

EID: 34247356039     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00624.2005     Document Type: Article

References (49)

1. Abbasi S, Su B, Kellems RE, Yang J, Xia Y. The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation. J Biol Chem 280: 36737-36746, 2005.
2. Brown PH, Chen TK, Birrer MJ. Mechanism of action of a dominantnegative mutant of c-Jun. Oncogene 9: 791-799, 1994.
3. Chen L, Glover JN, Hogan PG, Rao A, Harrison SC. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 392: 42-48, 1998.
4. Chen Q, Tu V, Wu Y, Bahl J. Hydrogen peroxide dose dependent induction of cell death or hypertrophy in cardiomyocytes. Arch Biochem Biophys 373: 242-248, 2000.
5. Chinenov Y, Kerppola TK. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20: 2438-2452, 2001.
6. Chow CW, Rincon M, Davis RJ. Requirement for transcription factor NFAT in interleukin-2 expression. Mol Cell Biol 19: 2300 -2307, 1999.
7. Coronella-Wood J, Terrand J, Sun H, Chen QM. c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes. J Biol Chem 279: 33567-33574, 2004.
8. 2+, calcineurin, and NF-AT. Cell 96: 611-614, 1999.
9. Dhar A, Hu J, Reeves R, Resar LM, Colburn NH. Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoterinduced transformation. Oncogene 23: 4466-4476, 2004.
10. Dong Z, Cmarik JL, Wendel EJ, Colburn NH. Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions. Carcinogenesis 15: 1001-1004, 1994.
11. Fujii T, Onohara N, Maruyama Y, Tanabe S, Kobayashi H, Fukutomi M, Nagamatsu Y, Nishihara N, Inoue R, Sumimoto H, Shibasaki F, Nagao T, Nishida M, Kurose H. Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J Biol Chem 280: 23041-23047, 2005.
12. Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000.
13. Griendling KK, Ushio-Fukai M. Reactive oxygen species as mediators of angiotensin II signaling. Regul Pept 91: 21-27, 2000.
14. Gullestad L, Aukrust P. The cytokine network in heart failure: pathogenetic importance and potential therapeutic targets. Heart Failure Monitor 2: 8-13, 2001.
15. Haq S, Choukroun G, Kang ZB, Ranu H, Matsui T, Rosenzweig A, Molkentin JD, Alessandrini A, Woodgett J, Hajjar R, Michael A, Force T. Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. J Cell Biol 151: 117-130, 2000.
16. Harris IS, Zhang S, Treskov I, Kovacs A, Weinheimer C, Muslin AJ. Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload. Circulation 110: 718-723, 2004.
17. Hirota H, Yoshida K, Kishimoto T, Taga T. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA 92: 4862-4866, 1995.
18. Ichida M, Finkel T. Ras regulates NFAT3 activity in cardiac myocytes. J Biol Chem 276: 3524-3530, 2001.
19. Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365: 352-355, 1993.
20. Josephson RA, Silverman HS, Lakatta EG, Stern MD, Zweier JL. Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes. J Biol Chem 266: 2354-2361, 1991.
21. Lim HW, De Windt LJ, Steinberg L, Taigen T, Witt SA, Kimball TR, Molkentin JD. Calcineurin expression, activation, and function in cardiac pressure-overload hypertrophy. Circulation 101: 2431-2437, 2000.
22. Lyakh L, Ghosh P, Rice NR. Expression of NFAT-family proteins in normal human T cells. Mol Cell Biol 17: 2475-2484, 1997.
23. Macian F, Garcia-Rodriguez C, Rao A. Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun. EMBO J 19: 4783-4795, 2000.
24. Macian F, Lopez-Rodriguez C, Rao A. Partners in transcription: NFAT and AP-1. Oncogene 20: 2476-2489, 2001.
25. Masuda ES, Imamura R, Amasaki Y, Arai K, Arai N. Signalling into the T-cell nucleus: NFAT regulation. Cell Signal 10: 599-611, 1998.
26. Mervaala E, Finckenberg P, Lapatto R, Muller DN, Park JK, Dechend R, Ganten D, Vapaatalo H, Luft FC. Lipoic acid supplementation prevents angiotensin II-induced renal injury. Kidney Int 64: 501-508, 2003.
27. Molkentin JD. Calcineurin and beyond: cardiac hypertrophic signaling. Circ Res 87: 731-738, 2000.
28. Molkentin JD, Dorn IG II. Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu Rev Physiol 63: 391-426, 2001.
29. Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93: 215-228, 1998.
30. Muller DN, Mervaala EM, Dechend R, Fiebeler A, Park JK, Schmidt F, Theuer J, Breu V, Mackman N, Luther T, Schneider W, Gulba D, Ganten D, Haller H, Luft FC. Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy. Am J Pathol 157: 111-122, 2000.
31. Murat A, Pellieux C, Brunner HR, Pedrazzini T. Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension. J Biol Chem 275: 40867-40873, 2000.
32. Nagata K, Somura F, Obata K, Odashima M, Izawa H, Ichihara S, Nagasaka T, Iwase M, Yamada Y, Nakashima N, Yokota M. AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats. Hypertension 40: 168-174, 2002.
33. Neilson J, Stankunas K, Crabtree GR. Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling. Curr Opin Immunol 13: 346-350, 2001.
34. Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A, Crabtree GR. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature 369: 497-502, 1994.
35. Palmer JN, Hartogensis WE, Patten M, Fortuin FD, Long CS. Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest 95: 2555-2564, 1995.
36. Peterson BR, Sun LJ, Verdine GL. A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1. Proc Natl Acad Sci USA 93: 13671-13676, 1996.
37. Prabhu SD. Cytokine-induced modulation of cardiac function. Circ Res 95: 1140-1153, 2004.
38. Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 15: 707-747, 1997.
39. Shih NL, Cheng TH, Loh SH, Cheng PY, Wang DL, Chen YS, Liu SH, Liew CC, Chen JJ. Reactive oxygen species modulate angiotensin II-induced beta-myosin heavy chain gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in neonatal rat cardiomyocytes. Biochem Biophys Res Commun 283: 143-148, 2001.
40. Siwik DA, Tzortzis JD, Pimental DR, Chang DL, Pagano PJ, Singh K, Sawyer DB, Colucci WS. Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro. Circ Res 85: 147-153, 1999.
41. Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science 281: 1690-1693, 1998.
42. Thaik CM, Calderone A, Takahashi N, Colucci WS. Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest 96: 1093-1099, 1995.
43. Thompson EJ, Gupta A, Stratton MS, Bowden GT. Mechanism of action of a dominant negative c-jun mutant in inhibiting activator protein-1 activation. Mol Carcinog 35: 157-162, 2002.
44. Tsatsanis C, Patriotis C, Tsichlis PN. Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB. Oncogene 17: 2609-2618, 1998.
45. Tu V, Bahl J, Chen Q. Signals of oxidant-induced hypertrophy of cardiac myocytes: key activation of phosphatidylinositol 3-kinase and p70S6 kinase. J Pharmacol Exp Ther 300: 1101-1110, 2002.
46. Tu V, Chen Q. Distinct roles of ERKs and p38 MAPK in oxidant induced cardiomyocyte hypertrophy. Cardiovasc Tox 3: 119 -133, 2003.
47. Xu LG, Li LY, Shu HB. TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis. J Biol Chem 279: 17278-17282, 2004.
48. 2 in angiotensin II-induced vascular hypertrophy. Hypertension 32: 488-495, 1998.
49. 2+/ calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. J Biol Chem 275: 15239-15245, 2000.