Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 10, 2007, Pages 3955-3960

  Mieczkowski, Piotr A ^a   Dominska, Margaret ^a   Buck, Michael J ^b   Lieb, Jason D ^b   Petes, Thomas D ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Chromatin; Meiosis; Sir2p; Yeast

Indexed keywords

DNA TOPOISOMERASE; DOUBLE STRANDED DNA; HISTONE DEACETYLASE; PROTEIN SPO11P; RIBOSOME RNA; SILENT INFORMATION REGULATOR PROTEIN 2; UNCLASSIFIED DRUG; DNA TOPOISOMERASE (ATP HYDROLYSING); FUNGAL DNA; SACCHAROMYCES CEREVISIAE PROTEIN; SPO11 PROTEIN, S CEREVISIAE;

ARTICLE; CHIMPANZEE; DNA SEQUENCE; DNA STRAND BREAKAGE; ENZYME MECHANISM; EUKARYOTE; FUNGAL STRAIN; GENE; GENE CLUSTER; GENE FREQUENCY; GENE LOCATION; GENE MUTATION; GENE REPRESSION; GENETIC RECOMBINATION; GENOME; MEIOSIS; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIR2 GENE; TELOMERE; WILD TYPE; BIOLOGICAL MODEL; CATALYSIS; CHROMATIN; DNA DAMAGE; DNA MICROARRAY; GENETICS; METABOLISM; OPEN READING FRAME; PHYSIOLOGY;

EUKARYOTA; PAN; SACCHAROMYCES CEREVISIAE;

CATALYSIS; CHROMATIN; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA, FUNGAL; GENOME; GENOME, FUNGAL; HISTONE DEACETYLASES; MEIOSIS; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OPEN READING FRAMES; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 34247259833     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700412104     Document Type: Article

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