Involvement of Sir2/4 in silencing of DNA breakage and recombination on mouse YACs during yeast meiosis

Molecular Biology of the Cell

Volumn 16, Issue 3, 2005, Pages 1449-1455

  Klieger, Yair ^a   Yizhar, Ofer ^a   Zenvirth, Drora ^a   Shtepel Milman, Neta ^a   Snoek, Margriet ^b   Simchen, Giora ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; FUNGAL DNA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 3;

AMINO ACID SEQUENCE; ARTICLE; CHROMATIN STRUCTURE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA RECOMBINATION; DNA STRAND BREAKAGE; FUNGAL GENE; FUNGAL STRAIN; FUNGUS MUTANT; GENE FUNCTION; GENE LOCATION; GENE MUTATION; GENE SILENCING; GENOME ANALYSIS; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX; MEIOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIR2 GENE; SIR3 GENE; SIR4 GENE; YEAST; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; CHROMATIN; CHROMOSOMES; CHROMOSOMES, ARTIFICIAL, YEAST; DNA; DNA DAMAGE; GENE SILENCING; GENOME; HISTONE DEACETYLASES; MEIOSIS; MICE; MODELS, GENETIC; MUTATION; PLASMIDS; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE; SIRTUINS;

EID: 14844288963     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E04-07-0592     Document Type: Article

References (38)

1. Blumental-Perry, A., Zenvirth, D., Klein, S., Onn, I., and Simchen, G. (2000). DNA motif associated with meiotic double-strand break regions in Saccharomyces cerevisiae. EMBO Rep. 1, 232-238.
2. Borde, V., Goldman, A., and Lichten, M. (2000). Direct coupling between meiotic DNA replication and recombination initiation. Science 290, 806-809.
3. Burke, D., and Olson, M. (1991). Preparation of clone libraries in yeast artificial-chromosome vectors. Methods Enzymol. 194, 251-270.
4. Cervantes, M., Farah, J., and Smith, G. (2000). Meiotic DNA breaks associated with recombination in S. pombe. Mol. Cell 5, 883-888.
5. Gasser, S., and Cockell, M. (2001). The molecular biology of the SIR proteins. Gene 279, 1-16.
6. Gottlieb, S., and Esposito, R. (1989). A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 10, 771-776.
7. Guillon, H., and de Massy, B. (2002). An initiation site for meiotic crossing-over and gene conversion in the mouse. Nat. Genet. 32, 296-299.
8. Haber, J. (1998). Mating-type gene switching in Saccharomyces cerevisiae. Annu. Rev. Genet. 32, 561-599.
9. Haring, S., Lautner, L., Comeron, J., and Malone, R. (2004). A test of the CoHR motif associated with meiotic double-strand breaks in Saccharomyces cerevisiae. EMBO Rep. 5, 41-46.
10. Hogstrand, K., and Bohme, J. (1997). Gene conversion of major histocompatibility complex genes in the mouse spermatogenesis is a premeiotic event. Mol. Biol. Cell 8, 2511-2517.
11. Hugerat, Y., and Simchen, G. (1993). Mixed segregation and recombination of chromosomes and YACs during single-division meiosis in spo13 strains of Saccharomyces cerevisiae. Genetics 135, 297-308.
12. Hugerat, Y., Spencer, F., Zenvirth, D., and Simchen, G. (1994). A versatile method for efficient YAC transfer between any two strains. Genomics 22, 108-117.
13. Ivy, J., Klar, A., and Hicks, J. (1986). Cloning and characterization of four SIR genes of Saccharomyces cerevisiae. Mol. Cell. Biol. 6, 688-702.
14. Kassir, Y., and Simchen, G. (1991). Monitoring meiosis and sporulation in Saccharomyces cerevisiae. Methods Enzymol. 194, 94-110.
15. Keeney, S. (2001). The mechanism and control of meiotic recombination initiation. Curr. Topics Dev. Biol. 52, 1-53.
16. Klar, A., Strathern, J., and Hicks, J. (1981). A position-effect control for gene transposition: state of expression of yeast mating-type genes affects their ability to switch. Cell 25, 517-524.
17. Klein, S., Zenvirth, D., Dror, V., Barton, A. B., Kaback, D. B., and Simchen, G. (1996a). Patterns of meiotic double-strand breakage on native and artificial yeast chromosomes. Chromosoma 105, 276-284.
18. Klein, S., Zenvirth, D., Sherman, A., Ried, K., Rappold, G., and Simchen, G. (1996b). Double-strand breaks on YACs during yeast meiosis may reflect meiotic recombination in the human genome. Nat. Genet. 13, 481-484.
19. Lien, S., Szyda, J., Schechinger, B., Rappold, G., and Arnheim, N. (2000). Evidence for heterogeneity in recombination in the human pseudoautosomal region: high resolution analysis by sperm typing and radiation-hybrid mapping. Am. J. Hum. Genet. 66, 557-566.
20. Luo, K., Vega-Palas, M. S., and Grunstein, M. (2002). Rap1-Sir4 binding independent of other Sir, y Nospacekuqq, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev. 16, 1528-1539.
21. Mahadevaiah, S., Turner, J., Baudat, F., Rogakou, E., de Boer, P., Blanco-Rodriguez, J., Jasin, M., Keeney, S., Bonner, W., and Burgoyne, P. (2001). Recombinational DNA double-strand breaks in mice precede synapsis. Nat. Genet. 27, 271-276.
22. Nasmyth, K. (1982). The regulation of yeast mating-type chromatin structure by SIR: an action at a distance affecting both transcription and transposition. Cell 30, 567-578.
23. Ried, K., Mertz, A., Nagaraja, R., Trusgnich, M., Riley, J. H., Anand, R., Lehrach, H., Page, D., Ellison, J. W., and Rappold, G. (1995). Characterization of a YAC contig spanning the pseudoautosomal region. Genomics 29, 787-792,
24. Sears, D. D., Hegemann, J. H., and Hieter, P. (1992). Meiotic recombination and segregation of human≠derived artificial chromosomes in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89, 5296-5300.
25. Sears, D. D., Hieter, P., and Simchen, G. (1994). An implanted recombination hot spot stimulates recombination and enhances sister chromatid cohesion of heterologous YACs during yeast meiosis. Genetics 138, 1055-1065.
26. Sherman, F. (1991). Getting started with yeast. Methods Enzymol. 194, 3-21.
27. Sherman, J., Stone, E., Freeman-Cook, L., Brachmann, C., Boeke, J., and Pillus, L. (1999). The conserved core of a human SIR2 homologue functions in yeast silencing. Mol. Biol. Cell 10, 3045-3059.
28. Smith, J. et al. (2000). A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA 97, 6658-6663.
29. Snoek, M., Teuscher, C., and Van Vugt, H. (1998). Molecular analysis of the major MHC recombinational hot spot located within the GFc gene of the murine class III region that is involved in diseases susceptibility. J. Immunol. 160, 266-272.
30. Snoek, M., van Dinten, L., and van Vugt, H. (1996). A novel gene, G7e, resembling a viral envelope gene, is located at the recombinational hot spot in the class III region of the mouse MHC. Genomics 15, 5-12.
31. Spencer, F., Hugerat, Y., Simchen, G., Hurko, O., Connelly, C., and Hieter, P. (1994). Yeast kar1 mutants provide an effective method for YAC transfer to new hosts. Genomics 22, 118-126.
32. Stone, E., Swanson, M., Romeo, A., Hicks, J., and Sternglanz, R. (1991). The SIR1 gene of Saccharomyces cerevisiae and its role as an extragenic suppressor of several mating-defective mutants. Mol. Cell. Biol. 11, 2253-2262.
33. Sun, H., Douglas, T., and Jack, W., Szostak. (1991). Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site. Cell 64, 1155-1161.
34. van Kooij, M., de Groot, K., van Vugt, H., Aten, J., and Snoek, M. (2001). Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region. Immunogenetics 53, 656-661.
35. Yang, Y., Chen, Y., Zhang, C., Nimmakayalu, M., Ward, D., and Weissman, S. (2000). Cloning and characterization of two mouse genes with homology to the yeast Sir2 gene. Genomics 69, 355-369.
36. Zenvirth, D., Arbel, T., Sherman, A., Goldway, M., Klein, S., and Simchen, G. (1992). Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae. EMBO J. 11, 3441-3447.
37. Zenvirth, D., Richler, C., Bardhan, A., Baudat, F., Barzilai, A., Wahrman, J., and Simchen, G. (2003). Mammalian meiosis involves DNA double-strand breaks with 3′ overhangs. Chromosoma 111, 369-376.
38. Zenvirth, D., and Simchen, G. (2000). Meiotic double-strand breaks in Schizosaccharomyces pombe. Curr. Genet. 38, 33-38.