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Volumn 129, Issue 4, 2007, Pages 696-705

Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants

Author keywords

13C labeling experiment; Artificial metabolite; Constraint based flux analysis; Converging ratio determinant (CRD); Gas chromatography mass spectrometry (GC MS); Metabolic flux

Indexed keywords

BIOTECHNOLOGY; ESCHERICHIA COLI; GAS CHROMATOGRAPHY; GENES; LINEAR PROGRAMMING; MASS SPECTROMETRY; METABOLISM;

EID: 34247254436     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2007.02.026     Document Type: Article
Times cited : (15)

References (22)
  • 1
    • 0037424661 scopus 로고    scopus 로고
    • Constraints-based models: regulation of gene expression reduces the steady-state solution space
    • Covert M.W., and Palsson B.O. Constraints-based models: regulation of gene expression reduces the steady-state solution space. J. Theor. Biol. 221 3 (2003) 309-325
    • (2003) J. Theor. Biol. , vol.221 , Issue.3 , pp. 309-325
    • Covert, M.W.1    Palsson, B.O.2
  • 2
    • 0034847930 scopus 로고    scopus 로고
    • Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis
    • Dauner M., Bailey J.E., and Sauer U. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis. Biotechnol. Bioeng. 76 2 (2001) 144-156
    • (2001) Biotechnol. Bioeng. , vol.76 , Issue.2 , pp. 144-156
    • Dauner, M.1    Bailey, J.E.2    Sauer, U.3
  • 3
    • 0001827017 scopus 로고    scopus 로고
    • Metabolic flux balance analysis
    • Lee S.Y., and Papoutsakis E.T. (Eds), Marcel Dekker, New York
    • Edwards J.S., Ramakrishna R., Schilling C.H., and Palsson B.O. Metabolic flux balance analysis. In: Lee S.Y., and Papoutsakis E.T. (Eds). Metabolic Engineering vol. 1 (1999), Marcel Dekker, New York 13-57
    • (1999) Metabolic Engineering , vol.1 , pp. 13-57
    • Edwards, J.S.1    Ramakrishna, R.2    Schilling, C.H.3    Palsson, B.O.4
  • 5
    • 0037335931 scopus 로고    scopus 로고
    • Metabolic flux profiling of Escherichia coli mutants in central carbon metabolism using GC-MS
    • Fischer E., and Sauer U. Metabolic flux profiling of Escherichia coli mutants in central carbon metabolism using GC-MS. Eur. J. Biochem. 270 5 (2003) 880-891
    • (2003) Eur. J. Biochem. , vol.270 , Issue.5 , pp. 880-891
    • Fischer, E.1    Sauer, U.2
  • 7
    • 0242475329 scopus 로고    scopus 로고
    • MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis
    • Lee D.Y., Yun H.S., Park S.W., and Lee S.Y. MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis. Bioinformatics 19 16 (2003) 2144-2146
    • (2003) Bioinformatics , vol.19 , Issue.16 , pp. 2144-2146
    • Lee, D.Y.1    Yun, H.S.2    Park, S.W.3    Lee, S.Y.4
  • 8
    • 27744478397 scopus 로고    scopus 로고
    • Systems-level analysis of genome-scale microbial metabolisms under the integrated software environment
    • Lee S.Y., Woo H.M., Lee D.Y., Choi H.S., Kim T.Y., and Yun H.S. Systems-level analysis of genome-scale microbial metabolisms under the integrated software environment. Biotechnol. Bioproc. Eng. 10 5 (2005) 425-431
    • (2005) Biotechnol. Bioproc. Eng. , vol.10 , Issue.5 , pp. 425-431
    • Lee, S.Y.1    Woo, H.M.2    Lee, D.Y.3    Choi, H.S.4    Kim, T.Y.5    Yun, H.S.6
  • 9
    • 0030571222 scopus 로고    scopus 로고
    • Pathway analysis, engineering and physiological considerations for redirecting central metabolism
    • Liao J.C., Hou S.Y., and Chao Y.P. Pathway analysis, engineering and physiological considerations for redirecting central metabolism. Biotechnol. Bioeng. 52 1 (1996) 129-140
    • (1996) Biotechnol. Bioeng. , vol.52 , Issue.1 , pp. 129-140
    • Liao, J.C.1    Hou, S.Y.2    Chao, Y.P.3
  • 10
    • 0042093610 scopus 로고    scopus 로고
    • The connectivity structure, giant strong component and centrality of metabolic networks
    • Ma H.W., and Zeng A.P. The connectivity structure, giant strong component and centrality of metabolic networks. Bioinformatics 19 11 (2003) 1423-1430
    • (2003) Bioinformatics , vol.19 , Issue.11 , pp. 1423-1430
    • Ma, H.W.1    Zeng, A.P.2
  • 11
    • 4243829380 scopus 로고    scopus 로고
    • Bidirectional reaction steps in metabolic networks. Part IV. Optimal design of isotopomer labeling experiments
    • Möllney M., Wiechert W., Kownatzki D., and de Graaf A.A. Bidirectional reaction steps in metabolic networks. Part IV. Optimal design of isotopomer labeling experiments. Biotechnol. Bioeng. 66 2 (1999) 86-103
    • (1999) Biotechnol. Bioeng. , vol.66 , Issue.2 , pp. 86-103
    • Möllney, M.1    Wiechert, W.2    Kownatzki, D.3    de Graaf, A.A.4
  • 12
    • 9544253891 scopus 로고    scopus 로고
    • Genome-scale models of microbial cell: evaluating the consequences of constraints
    • Price N.D., Reed J.L., and Palsson B.O. Genome-scale models of microbial cell: evaluating the consequences of constraints. Nat. Rev. Microbiol. 2 11 (2004) 886-897
    • (2004) Nat. Rev. Microbiol. , vol.2 , Issue.11 , pp. 886-897
    • Price, N.D.1    Reed, J.L.2    Palsson, B.O.3
  • 13
    • 0344328817 scopus 로고    scopus 로고
    • An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)
    • Reed J.L., Vo T.D., Schilling C.H., and Palsson B.O. An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Genome Biol. 4 9 (2003) R54
    • (2003) Genome Biol. , vol.4 , Issue.9
    • Reed, J.L.1    Vo, T.D.2    Schilling, C.H.3    Palsson, B.O.4
  • 15
    • 0033136109 scopus 로고    scopus 로고
    • Schilling, C.H., Schuster, S., Palsson, B.O., 1999. Heinrich, R. Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15 (3), 296-303.
  • 16
    • 0034615791 scopus 로고    scopus 로고
    • Theory for the systemic definition of metabolic pathway and their use in interpreting metabolic function from a pathway-oriented perspective
    • Schilling C.H., Letscher D., and Palsson B.O. Theory for the systemic definition of metabolic pathway and their use in interpreting metabolic function from a pathway-oriented perspective. J. Theor. Biol. 203 3 (2000) 229-248
    • (2000) J. Theor. Biol. , vol.203 , Issue.3 , pp. 229-248
    • Schilling, C.H.1    Letscher, D.2    Palsson, B.O.3
  • 17
    • 0034447725 scopus 로고    scopus 로고
    • Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems
    • Schilling C.H., Edwards J.S., Letscher D., and Palsson B.O. Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems. Biotechnol. Bioeng. 71 4 (2001) 286-306
    • (2001) Biotechnol. Bioeng. , vol.71 , Issue.4 , pp. 286-306
    • Schilling, C.H.1    Edwards, J.S.2    Letscher, D.3    Palsson, B.O.4
  • 18
    • 0343471424 scopus 로고    scopus 로고
    • Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices
    • Schmidt K., Carlsen M., Nielsen J., and Villaden J. Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices. Biotechnol. Bioeng. 55 6 (1997) 831-840
    • (1997) Biotechnol. Bioeng. , vol.55 , Issue.6 , pp. 831-840
    • Schmidt, K.1    Carlsen, M.2    Nielsen, J.3    Villaden, J.4
  • 19
    • 33746954260 scopus 로고    scopus 로고
    • A review on metabolic pathway analysis with emphasis on isotope labeling approach
    • Shimizu K. A review on metabolic pathway analysis with emphasis on isotope labeling approach. Biotechnol. Bioprocess. Eng. 7 5 (2002) 237-251
    • (2002) Biotechnol. Bioprocess. Eng. , vol.7 , Issue.5 , pp. 237-251
    • Shimizu, K.1
  • 20
    • 0033586461 scopus 로고    scopus 로고
    • Mass spectrometry for metabolic flux analysis
    • Wittmann C., and Heinzle E. Mass spectrometry for metabolic flux analysis. Biotechnol. Bioeng. 62 6 (1999) 739-750
    • (1999) Biotechnol. Bioeng. , vol.62 , Issue.6 , pp. 739-750
    • Wittmann, C.1    Heinzle, E.2
  • 21
    • 0034811345 scopus 로고    scopus 로고
    • Modeling and experimental design for metabolic flux analysis of lysine-producing Corynebacteria by mass spectrometry
    • Wittmann C., and Heinzle E. Modeling and experimental design for metabolic flux analysis of lysine-producing Corynebacteria by mass spectrometry. Metab. Eng. 3 2 (2001) 173-191
    • (2001) Metab. Eng. , vol.3 , Issue.2 , pp. 173-191
    • Wittmann, C.1    Heinzle, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.