An IL-7 splicing-defect lymphopenia mouse model revealed by genome-wide mutagenesis

Journal of Biomedical Science

Volumn 14, Issue 2, 2007, Pages 169-181

  Huang, Hong Wen ^a   Chiang, Yun Jung ^a   Hung, Shuen Iu ^b   Li, Chung Leung ^c   Yen, Jeffrey Jong Young ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

Author keywords

ENU mutagenesis; IL 7; Lymphopenia; Phenotype screening

Indexed keywords

AMINO ACID; DNA; ETHYLNITROSOUREA; INTERLEUKIN 7;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL LINEAGE; CELL SURVIVAL; CHEMICAL MUTAGENESIS; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DNA SPLICING; GENE IDENTIFICATION; GENE MAPPING; GENOTYPE; HEMATOPOIESIS; LYMPH NODE; LYMPHOCYTOPENIA; LYMPHOID TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCREENING TEST; SINGLE NUCLEOTIDE POLYMORPHISM; T CELL DEPLETION; THYMUS; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CELL LINE; CELL LINEAGE; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; ETHYLNITROSOUREA; GENOME; INTERLEUKIN-7; LYMPHOPENIA; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RNA SPLICING; RNA, MESSENGER; SEQUENCE DELETION; T-LYMPHOCYTES;

ANIMALIA; MUS;

EID: 34247224799     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-006-9135-1     Document Type: Article

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