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Volumn 321, Issue 2, 2007, Pages 608-615

Functional adenylyl cyclase inhibition in murine cardiomyocytes by 2′(3′)-O-(N-methylanthraniloyl)-guanosine 5′-[γ-thio] triphosphate

Author keywords

[No Author keywords available]

Indexed keywords

2'(3') O (N METHYLANTHRANILOYL) GUANOSINE 5' [GAMMA THIO]TRIPHOSPHATE; ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; CALCIUM CHANNEL L TYPE; ISOENZYME; ISOPRENALINE; UNCLASSIFIED DRUG;

EID: 34247216741     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.118422     Document Type: Article
Times cited : (16)

References (24)
  • 2
    • 0033835813 scopus 로고    scopus 로고
    • Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase
    • Defer N, Best-Belpomme M, and Hanoune J (2000) Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am J Physiol 279:F400-F416.
    • (2000) Am J Physiol , vol.279
    • Defer, N.1    Best-Belpomme, M.2    Hanoune, J.3
  • 5
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
    • Engelhardt S, Hein L, Wiesmann F, and Lohse MJ (1999) Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 96:7059-7064.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7059-7064
    • Engelhardt, S.1    Hein, L.2    Wiesmann, F.3    Lohse, M.J.4
  • 7
    • 2442714908 scopus 로고    scopus 로고
    • 2- adrenoceptor transgenic mice. Naunyn-Schmiedeberg's Arch Pharmacol 369:490-495.
    • 2- adrenoceptor transgenic mice. Naunyn-Schmiedeberg's Arch Pharmacol 369:490-495.
  • 8
    • 0003218037 scopus 로고    scopus 로고
    • Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice
    • Gao MH, Lai NC, Roth DM, Zhou J, Anzai T, Dalton N, and Hammond HK (1999) Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice. Circulation 99:1618-1622.
    • (1999) Circulation , vol.99 , pp. 1618-1622
    • Gao, M.H.1    Lai, N.C.2    Roth, D.M.3    Zhou, J.4    Anzai, T.5    Dalton, N.6    Hammond, H.K.7
  • 9
    • 2442506761 scopus 로고    scopus 로고
    • Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides
    • Gille A, Lushington GH, Mou T-C, Doughty MB, Johnson RA, and Seifert R (2004) Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides. J Biol Chem 279:19955-19969.
    • (2004) J Biol Chem , vol.279 , pp. 19955-19969
    • Gille, A.1    Lushington, G.H.2    Mou, T.-C.3    Doughty, M.B.4    Johnson, R.A.5    Seifert, R.6
  • 10
    • 0037630420 scopus 로고    scopus 로고
    • 2′(3′)-O-(N- Methylanthraniloyl)-substituted GTP analogs: A novel class of potent competitive adenylyl cyclase inhibitors
    • Gille A and Seifert R (2003) 2′(3′)-O-(N- Methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors. J Biol Chem 278:12672-12679.
    • (2003) J Biol Chem , vol.278 , pp. 12672-12679
    • Gille, A.1    Seifert, R.2
  • 11
    • 0035040818 scopus 로고    scopus 로고
    • Regulation and role of adenylyl cyclase isoforms
    • Hanoune J and Defer N (2001) Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol 41:145-174.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 145-174
    • Hanoune, J.1    Defer, N.2
  • 15
    • 0034623827 scopus 로고    scopus 로고
    • Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C
    • Kamp TJ and Hell JW (2000) Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res 87:1095-1102.
    • (2000) Circ Res , vol.87 , pp. 1095-1102
    • Kamp, T.J.1    Hell, J.W.2
  • 17
    • 0242637601 scopus 로고    scopus 로고
    • What is the role of β-adrenergic signaling in heart failure?
    • Lohse MJ, Engelhardt S, and Eschenhagen T (2003) What is the role of β-adrenergic signaling in heart failure? Circ Res 93:896-906.
    • (2003) Circ Res , vol.93 , pp. 896-906
    • Lohse, M.J.1    Engelhardt, S.2    Eschenhagen, T.3
  • 18
    • 14844299755 scopus 로고    scopus 로고
    • Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2′(3′)-O-(N-methylanthraniloyl)-guanosine 5-triphosphate
    • Mou T-C, Gille A, Fancy DA, Seifert R, and Sprang RA (2005) Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2′(3′)-O-(N-methylanthraniloyl)-guanosine 5-triphosphate. J Biol Chem 280:7253-7261.
    • (2005) J Biol Chem , vol.280 , pp. 7253-7261
    • Mou, T.-C.1    Gille, A.2    Fancy, D.A.3    Seifert, R.4    Sprang, R.A.5
  • 19
    • 33747624168 scopus 로고    scopus 로고
    • Broad specificity of mammalian adenylyl cyclase for interaction with 2′,3′-substituted purine- and pyrimidine nucleotide inhibitors
    • Mou TC, Gille A, Suryanarayana S, Richter M, Seifert R, and Sprang SR (2006) Broad specificity of mammalian adenylyl cyclase for interaction with 2′,3′-substituted purine- and pyrimidine nucleotide inhibitors. Mol Pharmacol 70:878-886.
    • (2006) Mol Pharmacol , vol.70 , pp. 878-886
    • Mou, T.C.1    Gille, A.2    Suryanarayana, S.3    Richter, M.4    Seifert, R.5    Sprang, S.R.6
  • 20
    • 0042859792 scopus 로고    scopus 로고
    • Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation
    • Okumura S, Kawabe J, Yatani A, Takagi G, Lee MC, Hong C, Liu J, Takagi I, Sadoshima J, Vatner DE, et al. (2003a) Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res 93:364-371.
    • (2003) Circ Res , vol.93 , pp. 364-371
    • Okumura, S.1    Kawabe, J.2    Yatani, A.3    Takagi, G.4    Lee, M.C.5    Hong, C.6    Liu, J.7    Takagi, I.8    Sadoshima, J.9    Vatner, D.E.10
  • 22
    • 0033554838 scopus 로고    scopus 로고
    • Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: Enhanced basal catalytic activity and function without increased cardiomyocyte β-adrenergic signaling
    • Tepe NM, Lorenz JN, Yatani A, Dash R, Krania EG, Dorn GW, and Liggett SB (1999) Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte β-adrenergic signaling. Biochemistry 38:16706-16713.
    • (1999) Biochemistry , vol.38 , pp. 16706-16713
    • Tepe, N.M.1    Lorenz, J.N.2    Yatani, A.3    Dash, R.4    Krania, E.G.5    Dorn, G.W.6    Liggett, S.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.