Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: Enhanced basal catalytic activity and function without increased cardiomyocyte β-adrenergic signalling

Biochemistry

Volumn 38, Issue 50, 1999, Pages 16706-16713

  Tepe, Nicole M ^a   Lorenz, John N ^a   Yatani, Atsuko ^a   Dash, Rajesh ^a   Kranias, Evangelia G ^a   Gerald W II, Dorn ^a   Liggett, Stephen B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; ISOPRENALINE;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEART MUSCLE CELL; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, WESTERN; CALCIUM CHANNELS, L-TYPE; CATALYSIS; ELECTROCARDIOGRAPHY; HEART FUNCTION TESTS; HEART RATE; MALE; MICE; MICE, TRANSGENIC; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION;

ANIMALIA; MUS MUSCULUS;

EID: 0033554838     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991619k     Document Type: Article

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