High-resolution mapping of the Gli3 deletion in the mouse extra-toes H mutant

Genesis (United States)

Volumn 45, Issue 3, 2007, Pages 107-112

  Genestine, Matthieu ^a,b   Robert, Benoît ^a   Lallemand, Yvan ^a  

^a INSTITUT PASTEUR   (France)

^b AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

Development; Genetic; Limb; Morphogenesis; Mouse

Indexed keywords

ALLELE; ANIMAL GENETICS; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; DELETION MUTANT; EMBRYO; EXTRA TOES; GENE; GENE DELETION; GENE MAPPING; GENE MUTATION; GLI3 GENE; HETEROZYGOTE; HOMOZYGOTE; LIMB; LIMB DISEASE; MORPHOGENESIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; WILD TYPE;

EID: 34247198965     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20270     Document Type: Article

References (19)

1. J allele generates a Gli3 fusion transcript. Mamm Genome 9:676-678.
2. Hubbard T, Andrews D, Caccamo M, Cameron G, Chen Y, Clamp M, Clarke L, Coates G, Cox T, Cunningham F, Curwen V, Cutts T, Down T, Durbin R, Fernandez-Kahari X, Gilbert J, Hammond M, Herrero J, Hotz H, Howe K, Iyer V, Jekosch K, Kanari A, Kasprzyk A, Keefe D, Keenan S, Kokocinsci F, London D, Longden I, McVicker G, Melsopp C, Meidl P, Potter S, Proctor G, Rae M, Rios D, Schuster M, Searle S, Severin J, Slater G, Smedley D, Smith J, Spooner W, Stabenau A, Staler J, Storey R, Trevanion S, Ureta-Vidal A, Vogel J, White S, Woodwark C, Birney E. 2005. Ensembl 2005. Nucleic Acids Res 33:447-444.
3. J mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3:241-246.
4. Johnson DR. 1967. Extra-toes: A new mutant gene causing multiple abnormalities in the mouse. J Embryol Exp Morphol 17:543-544.
5. Kang S, Graham J, Olney A, Biesecker L. 1997. GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Nat Genet 3:241-244.
6. Lyon MF, Morris T, Searle AG, Butler J. 1967. Occurences and linkage relations ot the mutant extra-toes in the mouse. Genet Res Camb 9:383-385.
7. J reveals a 51.5-kb deletion. Mamm Genome 13:58-61.
8. Pohl T, Mattei M-G, Rüther U. 1990. Evidence for allelism of the recessive insertional mutation add and the dominant mouse syndrome extra-toes (Xt). Development 110:1153-1157.
9. Radhakrishna U, Wild A, Grzeschik KH, Antonarakis S. 1997. Mutation in GLI3 in postaxial polydactyly type A. Nat Genet 17:269-271.
10. Ruppert JM, Vogelstein B, Arheden K, Kinzler KW. 1990. GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity. Mol Cell Biol 10:5408-5415.
11. Schimmang T, Lemaistre M, Vortkamp A, Rüther U. 1992. Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt). Development 116:799-804.
12. Schimmang T, Oda I, Rüther U. 1994. The mouse mutant Polydactyly Nagoya (Pdn) defines a novel allele of the zinc finger gene Gli3. Mamm Genome 5:384-386.
13. Thien H, Rüther U. 1999. The mouse mutation Pdn (Polydactyly Nagoya) is caused by the integration of a retrotransposon into the Gli3 gene. Mamm Genome 10:205-209.
14. Truett GE, Heeger P, Mynatt RL, Truett AA, Walker JA, Warman ML. 2000. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). Biotechniques 29:52-54.
15. Ueta E, Nanba E, Naruse I. 2002. Integration of a transposon into the Gli3 gene in the Pdn mutation. Congenit Anom (Kyoto) 42:318-322.
16. Van der Hoeven F, Schimmang T, Vortkamp A, Rüther U. 1993. Molecular linkage of the morphogenetic mouse mutation add and the zinc finger gene Gli3. Mamm Genome 4:276-277.
17. Vortkamp A, Gessler M, Grzeschik KH. 1991. GLI3 zinc finger gene interrupted by translocations in Greig syndrome families. Nature 352:539-544.
18. Vortkamp A, Franz T, Gessler M, Grzeschik KH. 1992. Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) on the mouse mutant extra toes (Xt). Mamm Genome 3:461-463.
19. Wang B, Fallon JF, Beachy PA. 2000. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100:423-434.