Discordant white matter N-acetylasparate and diffusion MRI measures suggest that chronic metabolic dysfunction contributes to axonal pathology in multiple sclerosis

NeuroImage

Volumn 36, Issue 1, 2007, Pages 19-27

  Cader, S ^a   Johansen Berg, H ^a   Wylezinska, M ^a   Palace, J ^b   Behrens, T E ^a   Smith, S ^a   Matthews, P M ^a,b,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RADCLIFFE INFIRMARY   (United Kingdom)

^c Research and Development   (United Kingdom)

Author keywords

Diffusion MRI; Magnetic resonance spectroscopy; Multiple sclerosis; Neurodegeneration; Neuropathology

Indexed keywords

N ACETYLASPARTIC ACID;

ADULT; ANISOTROPY; ARTICLE; BRAIN ATROPHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS CALLOSUM; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; MALE; METABOLIC DISORDER; MOTOR CORTEX; MOTOR NERVE; MULTIPLE SCLEROSIS; NERVE FIBER MEMBRANE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; WHITE MATTER;

ADULT; ASPARTIC ACID; AXONS; BRAIN; CORPUS CALLOSUM; DIFFUSION MAGNETIC RESONANCE IMAGING; DOMINANCE, CEREBRAL; ENERGY METABOLISM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NERVE FIBERS, MYELINATED; REFERENCE VALUES;

EID: 34247197112     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2007.02.036     Document Type: Article

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