HeLa cells treated with phytoglycoprotein (150 kDa) were killed by activation of caspase 3 via inhibitory activities of NF-κB and AP-1

Journal of Biomedical Science

Volumn 14, Issue 2, 2007, Pages 223-232

  Oh, Phil Sun ^a   Lim, Kye Taek ^a  

^a Chonnam National University   (South Korea)

Author keywords

Apoptosis; Caspase 3; Nitric oxide; SNL glycoprotein; Transcription factor

Indexed keywords

CASPASE 3; GLYCOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHYTOGLYCOPROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL KILLING; CONTROLLED STUDY; DNA BINDING; DRUG DNA BINDING; DRUG INHIBITION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SOLANUM NIGRUM; TRADITIONAL MEDICINE;

APOPTOSIS; CASPASE 3; GLYCOPROTEINS; HELA CELLS; HUMANS; NF-KAPPA B; NITRIC OXIDE; PLANT PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA;

SOLANUM NIGRUM;

EID: 34247196576     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-006-9140-4     Document Type: Article

References (34)

1. World Health Organization (2003) The global burden of cancer. In: B.W. Stewart and P. Kleihues, Editors, World Cancer Report, IARC Press, Washington DC, p. 13.
2. Shin H.R., Jung K.W., Won Y.J. and Park J.G., 2002 Annual report of the Korea Central Cancer Registry: based on registered from 139 hospitals. Cancer Res. Treat. 36: 103-114, 2004.
3. Ledwaba T., Dlamini Z., Naicker S. and Bhoola K., Molecular genetics of human cervical cancer: role of papillomavirus and the apoptotic cascade. Biol. Chem. 385: 671-682, 2004.
4. Kaufmann S.H. and Hengartner M.O., Programmed cell death: alive and well in the new millennium. Trends Cell. Biol. 11: 526-534, 2001.
5. Negoescu A., Apoptosis in cancer: therapeutic implications. Histol. Histopathol. 15: 281-297, 2000.
6. Karin M., Liu Z.G. and Zandi E., AP-1 function and regulation. Curr. Opin. Cell Biol. 9: 240-246, 1997.
7. Wang C.Y., Cusack J.C. Jr., Liu R. and Baldwin A.S. Jr., Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NFkB. Nat. Med. 5: 412-417, 1999.
8. Nakshatri H., Bhat-Nakshatri P., Martin D.A., Goulet R.J. Jr. and Sledge G.W. Jr., Constitutive activation of NF-kB during progression of breast cancer to hormone-independent growth. Mol. Cell Biol. 17: 3629-3639, 1997.
9. Young M.R., Farrell L., Lambert P., Awasthi P. and Colburn N.H., Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-jun. Mol. Carcinog. 34: 72-77, 2002.
10. Hatano E., Bennett B.L., Manning A.M., Qian T., Lemasters J.J. and Brenner D.A., NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Gastroenterology 120: 1251-1262, 2001.
11. Lala P.K. and Chakraborty C., Role of nitric oxide in carcinogenesis and tumour progression. Lancet. Oncol. 2: 149-156, 2001.
12. Oka K., Suzuki Y., Iida H. and Nakano T., Pd-ECGF positivity correlates with better survival, while iNOS has no predictive value for cervical carcinomas treated with radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 57: 217-221, 2003.
13. Sandhya T., Lathika K.M., Pandey B.N. and Mishra K.P., Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett. 231: 206-214, 2006.
14. Kim J.B., Koo H.N., Joeng H.J., Lyu Y.S., Park S.G., Won J.H., Kim Y.K., Hong S.H. and Kim H.M., Induction of apoptosis by Korean medicine Gagam-whanglyun-haedoktang through activation of caspase-3 in human leukemia cell line, HL-60 cells. J. Pharmacol. Sci. 97: 138-145, 2005.
15. Zhongyso D. (ed.), Chines Drug Dictionary, vol. 1. Shanghai Science and Technology, Shanghai, 1978, pp. 630-631.
16. Lee S.J. and Lim K.T., Antioxidative effects of glycoprotein isolated from Solanum nigrum Linne on oxygen radicals and its cytotoxic effects on the MCF-7 Cell. J. Food Sci. 68: 466-470, 2003.
17. Lee S.J., Ko J.H., Lim K. and Lim K.T., 150 kDa glycoprotein isolated from Solanum nigrum Linne enhances activities of detoxicant enzymes and lowers plasmic cholesterol in mouse. Pharmacol. Res. 51: 399-408, 2005.
18. Bergmeyer H.U., Bernt E. (1974) Lactate dehydrogenase. In: Bergmeyer H.U. (eds) Methods of Enzymatic Analysis, 2nd edition. Academic Press, New York, pp. 574-579.
19. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S. and Tannenbaum S.R., Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal. Biochem. 126: 131-138, 1982.
20. Lowry O.H., Rosebrough N.J., Farr A.L. and Randall R.J., Protein measurement with the folin-phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
21. Hu W. and Kavanagh J.J., Anticancer therapy targeting the apoptotic pathway. Lancet Oncol. 4: 721-729, 2003.
22. Gupta M., Mazumder U.K., Kumar R.S., Sivakumar T. and Vamsi M.L., Antitumor activity and antioxidant status of Caesalpinia bonducella against Ehrlich ascites carcinoma in Swiss albino mice. J. Pharmacol. Sci. 94: 177-184, 2004.
23. Herrera-Arellano A., Aguilar-Santamaria L., Garcia-Hernandez B., Nicasio-Torres P. and Tortoriello J., Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics. Phytomedicine 11: 561-566, 2004.
24. Johnstone S.A., Gelmon K., Mayer L.D., Hancock R.E. and Bally M.B., In vitro characterization of the anticancer activity of membraneactive cationic peptides. I. Peptidemediated cytotoxicity and peptideenhanced cytotoxic activity of doxorubicin against wild-type and pglycoprotein over-expressing tumor cell lines. Anticancer Drug Des. 15: 151-160, 2000.
25. Zhang W.M., Lai Z.S., He M.R., Xu G., Huang W. and Zhou D.Y., Effects of the antibacterial peptide cecropins from Chinese oak silkworm, Antheraea pernyi on 1, 2-dimethylhydrazine-induced colon carcinogenesis in rats. Di Yi Jun Yi Da Xue Xue Bao 23: 1066-1068, 2003.
26. Danpure C.J., Lactate dehydrogenase and cell injury. Cell Biochem. Funct. 2: 144-148, 1984.
27. Thompson C.B., Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462, 1995.
28. Cho S.G. and Choi E.J., Apoptotic signaling pathways: caspases and stress-activated protein kinases. J. Biochem. Mol. Biol. 35: 24-27, 2002.
29. Ashkenazi A. and Dixit V.M., Death receptors: signaling and modulation. Science 281: 1305-1308, 1998.
30. Salvesen G.S. and Dixit V.M., Caspases: intracellular signaling by proteolysis. Cell 91: 443-446, 1997.
31. Desagher S. and Martinou J.C., Mitochondria as the central control point of apoptosis. Trends Cell Biol. 10: 369-377, 2000.
32. Liu R.H. and Hotchkiss J.H., Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat. Res. 339: 73-89, 1995.
33. Dimmeler S., Haendeler J., Nehls M. and Zeiher A.M., Suppression of apoptosis by nitric oxide via inhibition of interleukin-1betaconverting enzyme (ICE)-like and cysteine protease protein (CPP)- 32-like proteases. J. Exp. Med. 185: 601-607, 1997.
34. Chen H.H., Su W.C., Chou C.Y., Guo H.R., Ho S.Y., Que J. and Lee W.Y., Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 63: 1093-1100, 2005.