Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4-CD8- to CD4 +CD8+ transition

Neoplasia

Volumn 9, Issue 4, 2007, Pages 315-321

  Cheng, Yue ^a   Zhang, Zhenhua ^a   Slape, Christopher ^a   Aplan, Peter D ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Navy 8 ^*  (United States)

Author keywords

Cre LoxP; SCL; SIL; T ALL; T cell development

Indexed keywords

CRE RECOMBINASE; PROTEIN KINASE LCK; T LYMPHOCYTE ACUTE LYMPHOBLASTIC LEUKEMIA 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACUTE LYMPHOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BREEDING; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CELL MATURATION; EMBRYO; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE FUSION; GENE LOCUS; GENETIC RECOMBINATION; INTRON; LOXP SITE; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; T LYMPHOCYTE; THYMOCYTE; THYMUS; TRANSGENE; TRANSGENIC MOUSE; TUMOR GENE;

EID: 34247181622     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.07148     Document Type: Article

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