Crystal structure of the Tp34 (TP0971) lipoprotein of Treponema pallidum: Implications of its metal-bound state and affinity for human lactoferrin

Journal of Biological Chemistry

Volumn 282, Issue 8, 2007, Pages 5944-5958

  Deka, Ranjit K ^a   Brautigam, Chad A ^a   Tomson, Farol L ^a   Lumpkins, Sarah B ^b   Tomchick, Diana R ^a   Machius, Mischa ^a   Norgard, Michael V ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN LACTOFERRINS; LACTOFERRIN BINDING PROPERTIES; LIPOPROTEINS; SYPHILIS;

BIOCHEMISTRY; CENTRIFUGATION; CRYSTAL STRUCTURE; DIMERS; PROTEINS; STOICHIOMETRY; ZINC;

PATHOGENS;

ION; LACTOFERRIN; LIPOPROTEIN; METHIONINE; PROTEIN TP34; UNCLASSIFIED DRUG; ZINC; MEMBRANE PROTEIN; PERIPLASMIC PROTEIN; RECOMBINANT PROTEIN;

ARTICLE; BACTERIAL INFECTION; BINDING SITE; CALORIMETRY; CONTROLLED STUDY; CRYSTAL STRUCTURE; METAL BINDING; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; STOICHIOMETRY; TREPONEMA PALLIDUM; ULTRACENTRIFUGATION; CHEMISTRY; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SYPHILIS; X RAY CRYSTALLOGRAPHY;

TREPONEMA PALLIDUM;

CRYSTALLOGRAPHY, X-RAY; HUMANS; LACTOFERRIN; LIPOPROTEINS; MEMBRANE PROTEINS; PERIPLASMIC PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SYPHILIS; TREPONEMA PALLIDUM; ZINC;

EID: 34247170432     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610215200     Document Type: Article

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