In vitro activity of aurein 1.2 alone and in combination with antibiotics against gram-positive nosocomial cocci

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 4, 2007, Pages 1494-1496

  Giacometti, Andrea ^a,c   Cirioni, Oscar ^a   Riva, Alessandra ^a   Kamysz, Wojciech ^b   Silvestri, Carmela ^a   Nadolski, Piotr ^b   Della Vittoria, Agnese ^a   Łukasiak, Jerzy ^b   Scalise, Giorgio ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c Ospedale Regionale Torrette   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPHIBIAN PROTEIN; AUREIN 1.2; CLARITHROMYCIN; IMIPENEM; LINEZOLID; MINOCYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATE; CELL LINE; DRUG CYTOTOXICITY; DRUG POTENTIATION; ENTEROCOCCUS FAECALIS; EVALUATION; GRAM POSITIVE COCCI; HOSPITAL INFECTION; HUMAN; HUMAN CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CROSS INFECTION; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; GRAM-POSITIVE COCCI; MICROBIAL SENSITIVITY TESTS;

EID: 34247155177     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00666-06     Document Type: Article

References (17)

1. Bevins, C. L., and M. Zasloff. 1990. Peptides from frog skin. Annu. Rev. Biochem. 59:395-414.
2. Burke, J. P. 2003. Infection control-a problem for patient safety. N. Engl. J. Med. 348:651-656.
3. Clinical and Laboratory Standards Institute. 2003. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A6. Clinical and Laboratory Standards Institute, Wayne, PA.
4. Cormican, M. G., and R. N. Jones. 1996. Emerging resistance to antimicrobial agents in Gram-positive bacteria. Enterococci, staphylococci and non-pneumococcal streptococci. Drugs 51:S6-S12.
5. Eliopoulos, G. M., and R. C. Moellering, Jr. 1996. Antimicrobial combinations, p. 330-393. In V. Lorian (ed.), Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, Md.
6. Fields, G. B., and R. L. Noble. 1990. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int. J. Pept. Protein Res. 35:161-214.
7. Giacometti, A., O. Cirioni, W. Kamysz, G. D'Amato, C. Silvestri, M. S. Del Prete, A. Licci, A. Riva, J. Łukasiak, and G. Scalise. 2005. In vitro activity of the histatin derivative P-113 against multidrug-resistant pathogens responsible for pneumonia in immunocompromised patients. Antimicrob. Agents Chemother. 49:1249-1252.
8. Hancock, R. E. W., and D. S. Chapple. 1999. Peptide antibiotics. Antimicrob. Agents Chemother. 43:1317-1323.
9. Hancock, R. E. W., and M. G. Scott. 2000. The role of antimicrobial peptides in animal defenses. Proc. Natl. Acad. Sci. USA 97:8856-8861.
10. Hiemstra, P. S., B. A. Fernie-King, J. McMichael, P. J. Lachmann, and J. M. Sallenave. 2004. Antimicrobial peptides: mediators of innate immunity as templates for the development of novel anti-infective and immune therapeutics. Curr. Pharm. Des. 10:2891-2905.
11. McCafferty, D. G., P. Cudic, M. K. Yu, D. C. Behenna, and R. Kruger. 1999. Synergy and duality in peptide antibiotic mechanisms. Curr. Opin. Chem. Biol. 3:672-680.
12. Rinaldi, A. C. 2002. Antimicrobial peptides from amphibian skin: an expanding scenario. Curr. Opin. Chem. Biol. 6:799-804.
13. Rozek, T., J. H. Bowie, J. C. Wallace, and M. J. Tyler. 2000. The antibiotic and anticancer active aurein peptides from the Australian bell frogs Litoria aurea and Litoria raniformis. Part 2. Sequence determination using electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 14:2002-2011.
14. Rozek, T., K. L. Wegener, J. H. Bowie, I. N. Olver, J. A. Carver, J. C. Wallace, and M. J. Tyler. 2000. The antibiotic and anticancer active aurein peptides from the Australian bell frogs Litoria aurea and Litoria raniformis: the solution structure of aurein 1.2. Eur. J. Biochem. 267:5330-5341.
15. Shai, Y. 2002. Mode of action of membrane active antimicrobial peptides. Biopolymers 66:236-248.
16. Vaara, M., and M. Porro. 1996. Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria. Antimicrob. Agents Chemother. 40:1801-1805.
17. Viljanen, P., H. Matsunaga, Y. Kimura, and M. Vaara. 1991. The outer membrane permeability-increasing action of deacylpolymyxins. J. Antibiot. 44:517-523.