siRNA targeting PLK-1 induces apoptosis of synoviocytes in rheumatoid arthritis

Biochemical and Biophysical Research Communications

Volumn 357, Issue 2, 2007, Pages 353-359

  Wada, Makoto ^a   Kawahito, Yutaka ^a   Kimura, Shinya ^b   Kohno, Masataka ^a   Ishino, Hidetaka ^a   Kimura, Mizuho ^a   Omoto, Atsushi ^a   Yamamoto, Aihiro ^a   Hamaguchi, Masahide ^a   Tsubouchi, Yasunori ^a   Tokunaga, Daisaku ^a   Hojo, Tatsuya ^a   Ashihara, Eishi ^b   Maekawa, Taira ^b   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Apoptosis; PLK 1; Rheumatoid arthritis; siRNA; Synoviocyte

Indexed keywords

INTERLEUKIN 1BETA; POLO LIKE KINASE 1; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; BONE DESTRUCTION; CELL GROWTH; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE REPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MONONUCLEAR CELL; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM; WESTERN BLOTTING;

APOPTOSIS; ARTHRITIS, RHEUMATOID; CELL CYCLE PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; GENE SILENCING; GENE TARGETING; HUMANS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; SYNOVIAL FLUID;

EID: 34247154965     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.03.190     Document Type: Article

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