Inhibition of inducible nitric oxide synthase in murine visceral larva migrans: Effects on lung and liver damage

Chinese Journal of Physiology

Volumn 49, Issue 6, 2006, Pages 326-334

  Demirci, Cihan ^a   Gargili, Aysen ^b   Kandil, Asli ^a   Cetinkaya, Handan ^a   Uyaner, Ilhan ^a   Boynuegri, Basak ^b   Koray Gumustas, M ^b  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

iNOS; Oxidative stress; Toxocara canis; Visceral larva migrans

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE;

ANIMAL; ARTICLE; DOG; ENZYME INDUCTION; ENZYMOLOGY; FEMALE; LARVA; LIVER; LUNG; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; TOXOCARA CANIS; VISCERAL LARVA MIGRANS SYNDROME;

ANIMALS; DOGS; ENZYME INDUCTION; FEMALE; LARVA; LARVA MIGRANS, VISCERAL; LIVER; LUNG; MICE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; TOXOCARA CANIS;

EID: 34247122365     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Ascenzi, P., and Gradoni, L. Nitric oxide limits parasite development in vectors and in invertebrate intermediate hosts. IUBMB Life 53: 121-123, 2002.
2. Bergmeyer, H.U., Scheibe, P. and Wahlefeld, A.W. Optimization of methods for aspartate aminotransferase and alanine aminotransferase. Clin. Chem. 24: 58-73, 1978.
3. Bowman, J.W., Winterrowd, C.A., Friedman, A.R., Thompson, D.P., Klein, R.D., Davis, J.P., Maule, A.G., Blair, K.L. and Geary, T.G. Nitric oxide mediates the inhibitory effects of SDPNFLRFamide, a nematode FMRFamide-related neuropeptide, in Ascaris suum. J. Neurophysiol. 74: 1880-1888, 1995.
4. Brunet, L.R., Beall, M., Dunne, D.W. and Pearce, E.J. Nitric oxide and the Th2 response combine to prevent severe hepatic damage during Schistosoma mansoni infection. J. Immunol. 163: 4976-4984, 1999.
5. Brunet, L.R., Finkelman, F.D., Cheever, A.W., Kopf, M.A. and Pearce, E.J. IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis. J. Immunol. 159: 777-785, 1997.
6. Buege, J.A. and Aust, S.D. Microsomal lipid peroxydation. Methods Enzymol. 12: 302-310, 1978.
7. El-Sokkary, G.H., Omar, H.M., Hassanein, A.M.M., Cuzzocrea, S. and Reiter, R.J. Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. Free Radic. Biol. Med. 32: 319-332, 2002.
8. Espinosa, E., Perez Arellano, J.L., Ciarranza, C., Collia, F. and Muro, A. In vivo inhibition of inducible nitric oxide synthase decreases lung injury induced by Toxocara canis in experimentally infected rats. Parasite Immunol. 24: 511-520, 2002.
9. Espinoza, E., Perez-Arellano, J.L., Vicente, B. and Muro, A. Cytoplasmic signaling pathways in alveolar macrophages involved in the production of nitric oxide after stimulation with excretory/ secretory antigens of Toxocara canis. Parasite Immunol. 24: 535-544, 2002.
10. Espinoza, E., Muro, A., Sanchez-Martin, M.M., Casanueva, P. and Perez-Arellano, J.L. Toxocara canis antigens stimulate the production of nitric oxide and prostaglandin E2 by rat alveolar macrophages. Parasite Immunol. 24: 311-319, 2002.
11. Fan, C.K., Lin, Y.H., Hung, C.C., Chang, S.F. and Su, K.E. Enhanced inducible nitric oxide synthase expression and nitrotyrosine accumulation in experimental granulomatous hepatitis caused by Toxocara canis in mice. Parasite Immunol. 26:273-281, 2004.
12. Galvin, T. Experimental Toxocara canis infections in chickens and pigeons. J. Parasitol. 50: 124-127, 1964.
13. Gargl, A., Demirci, C., Kandil, A., Cetinkaya, H., Atukeren, P. and GümüStaS, M.K. In vivo inhibition of inducible nitric oxide and evaluation of the brain tissue damage induced by Toxocara canis larvae in experimentally infected mice. Chinese J. Physiol. 47: 189-196, 2004.
14. Garside, P., Kennedy, M.W., Wakelin, D. and Lawrence, C.E. Immunopathology of intestinal helminth infection. Parasite Immunol. 22: 605-612, 2000.
15. Garthwaite, J. Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci. 14: 60-67, 1991.
16. James, S.L. Role of nitric oxide in parasitic infections. Microbiol. Rev. 59: 533-547, 1995.
17. Khan, I.A., Schwartzman, J.D., Matsuura, T. and Kasper, L.H. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. Proc. Natl. Acad. Sci. USA 94: 13955-13960, 1997.
18. Lawrence, C.E., Paterson, J.C., Wei, X.Q., Liew, F.Y., Garside, P. and Kennedy, M.W. Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spiralis infection in mice. J. Immunol. 164: 4229-4234, 2000.
19. Nilsson, B.O. Biological effects of aminoguanidine: an update. Inflamm. Res. 48: 509-515, 1999.
20. Oliveira, F.J. and Cecchini, R. Oxidative stress of liver in hamsters infected with Leishmania (L.) chagasi. J. Parasitol. 86: 1067-1072, 2000.
21. Oshima, T. Standardization of techniques for infecting mice with Toxocara canis and observations on the normal migration routes of the larvae. J. Parasitol. 47: 652-656, 1961.
22. Oswald, I.P. and James, S.L. Nitrogen oxide in host defense against parasites. Methods 10: 8-14, 1996.
23. Oswald, I.P., Wynn, T.A., Sher, A. and James, S.L. NO as an effector molecule of parasite killing: modulation of its synthesis by cytokines. Comp. Biochem. Physiol. Pharmacol. Toxicol. Endocrinol. 108: 11-18, 1994.
24. Palmer, R.M.J., Ferrige, A.G. and Moncada, S. Nitric oxide release accounts for the biological activity of endothelium derived-relaxing factor. Nature 327: 524-526, 1987.
25. Rajan, T.V., Porte, P., Yates, J.A., Keefer, L. and Schultz, L.D. Role of nitric oxide in host defence against an extracellular, metazoan parasite, Brugia malayi. Infect. Immun. 64: 3351-3353, 1996.
26. Schluter, D., Deckert, M., Hof, H. and Frei, K. Toxoplasma gondii infection of neurons induces neuronal cytokine and chemokine production, but gamma interferon-and tumor necrosis factorstimulated neurons fail to inhibit the invasion and growth of T. gondii. Infect. Immun. 69: 7889-7893, 2001.
27. Selkirk, M.E., Smith, V.P., Thomas, G.R. and Gounaris, K. Resistance of filarial nematode parasites to oxidative stress. Int. J. Parasitol. 28: 1315-1332, 1998.
28. Soh, C. T. The distribution and persistence of hookworm larvae in the tissues of mice in relation to species and to route of inoculation. J. Parasitol. 44: 515-519, 1958.
29. Sun, Y., Oberley, L.W. and Li, Y.A. Simple method for clinical assay of superoxide dismutase. Clin. Chem. 34: 497-500, 1988.
30. Taylor, B.S., Alarcon, L.H. and Billiar, T.R. Inducible nitric oxide synthase in the liver: regulation and function. Biochemistry 63: 766-781, 1998.
31. Taylor, M.J., Cross, H.F., Mohammed, A.A., Trees, A.J. and Bianco, A.E. Susceptibility of Brugia malayi and Onchocerca lienalis microfilariae to nitric oxide and hydrogen peroxide in cellfree culture and from IFN gamma-activated macrophages. Parasitology 112: 315-322, 1996.
32. Wandurska-Nowak, E. and Wisniewska, J. Release of nitric oxide during experimental trichinellosis in mice. Parasitol. Res. 88: 708-711, 2002.
33. Wynn, T.A., Oswald, I.P., Eltoum, I.A., Caspar, P., Lowenstein, C. J., Lewis, F.A., James, S.L. and Sher, A. Elevated expression of Th1 cytokines and NO synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni. J. Immunol. 153: 5200-5209, 1994.