In vivo inhibition of inducible nitric oxide and evaluation of the brain tissue damage induced by Toxocara canis larvae in experimentally infected mice

Chinese Journal of Physiology

Volumn 47, Issue 4, 2004, Pages 189-196

  Gargili, Ayşen ^a   Demirci, Cihan ^a   Kandil, Asli ^a   Çetinkaya, Handan ^a   Atukeren, Pinar ^a   Gümüştaş, M Koray ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

iNOS; NADPH d; Oxidative stress; T. canis

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; BRAIN TISSUE; CONTROLLED STUDY; ENZYME INHIBITION; EXPERIMENTAL MOUSE; HISTOCHEMISTRY; IN VIVO STUDY; LARVA; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; TOXOCARA CANIS; TOXOCARIASIS;

EID: 11344285042     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Barriga, O.O. A critical look at the importance, prevalence and control of toxocariasis and the possibilities of immunological control. Vet. Parasitol. 29: 195-234, 1988.
2. Blos, M., Schleicher, U., Janaina Soares Rocha, F., Meissner, U., Röllinghoff, M., and Bogdan, C. Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase. Eur. J. Immunol. 33: 1224-1234, 2003.
3. Bogdan, C. Nitric oxide and the immune response. Nat. Immunol. 2: 907-916, 2001.
4. Buege, J.A. and Aust, S.D. Microsomal lipid peroxydation. Methods Enzymol. 12: 302-310, 1978.
5. Clark, I.A. and Rockett, K.A. Nitric oxide and parasitic diseases. Adv. Parasitol. 37: 1-56, 1996.
6. Dai, W.J., Waldvogel, A., Jungi, T., Stettler, M. and Gottstein, B. Inducible nitric oxide synthase deficiency in mice increases resistance to chronic infection with Echinococcus multilocularis. Immunology 108: 238-244, 2003.
7. Espinosa, E., Perez Arellano, J.L., Ciarranza, C., Collia, F. and Muro, A. In vivo inhibition of inducible nitric oxide synthase decreases lung injury induced by Toxocara canis in experimentally infected rats. Parasite Immunol. 24: 511-520, 2002.
8. Espinoza, E., Muro, A., Sanchez-Martin, M.M., Casanueva, P. and Perez-Arellano, J.L. Toxocara canis antigens stimulate the production of nitric oxide and prostoglandin E2 by rat alveolar macrophages. Parasite Immunol. 24: 311-319, 2002.
9. Espinoza, E., Perez-Arellano, J.L., Vicente, B. and Muro, A. Cytoplasmic signaling pathways in alveolar macrophages involved in the production of nitric oxide after stimulation with excretory/secretory antigens of Toxocara canis. Parasite Immunol. 24: 535-544, 2002.
10. Galvin, T. Experimental Toxocara canis infections in chickens and pigeons. J. Parasitol. 50: 124-127, 1964.
11. Garside, P., Kennedy, M.W., Wakelin, D. and Lawrence, C.E. Immunopathology of intestinal helminth infection. Parasite Immunol. 22: 605-612, 2000.
12. Glickman, L.T. and Shofer, F.S. Zoonotic visceral and ocular larva migrans. Vet. Clin. N. Am.-Small, 17: 39-53, 1987.
13. Harald, H.H., Schmidt, W. and Walter, U. NO at work. Cell 78: 919-925, 1994.
14. Hartleb, M. and Januszewski, K. Severe hepatic involvement in visceral larva migrans. Eur. J. Gastroen Hepat. 13: 1245-1249, 2001.
15. Hope, B.T., Michael, G.J., Knigge, K.M. and Vincent, S.R. Neuronal NADPH diaphorase is a nitric oxide synthase. P. Natl. Acad. Sci. 88: 2811-2814, 1991.
16. James, S. L. The effector function of nitrogen oxides in host defence against parasites. Exp. Parasitol. 73: 223-226, 1991.
17. Kaplan, K.J., Goodman, Z.D. and Ishak, K.G. Eosinophilic granuloma of the liver. Am. J. Surg. Pathol. 25: 1316-1321, 2001.
18. Khan, I.A., Schwartzman, J.D., Matsuura, T. and Kasper, L.H. A Dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. P. Natl. Acad. Sci. USA, 94: 13955-13960, 1997.
19. Lawrence, C.E., Paterson, J.C.M., Wei, X., Liew, F.Y., Garside, P. and Kennedy, M.W. Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spiralis infection in mice. J. Immunol. 164: 4229-4234, 2000.
20. Miller, R.A. and Britigan, B.E. Role of oxidants in microbial pathophysiology. Clin. Microbiol. Rev. 1: 18, 1997.
21. Nagakura, K., Tachibana, H., Kaneda, Y. and Kato, Y. Toxocariasis possibly caused by ingesting raw chicken. J. Infect. Dis. 160: 735-736, 1989.
22. Nathan, C. Nitric oxide as a secrotory product of mammalian cells. FASEB J. 6: 3051-3064, 1992.
23. Nathan, C. and Xie, Q.W. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 13: 269, 13725-13728, 1994.
24. Nilsson, B.O. Biological effects of aminoguanidine: an update. Inflamm. Res. 48: 509-515, 1999.
25. Overgaauw, P.A.M. Aspects of Toxocara epidemiology: Human Toxocarosis. Crit. Rev. Microbiol. 23: 215-231, 1997.
26. Rajan, T.V., Porte, P., Yates, J.A., Keefer, L. and Schultz, L.D. Role of nitric oxide in host defence against an extracellular, metazoan parasite, Brugia malayi. Infect. Immun. 64: 3351-3353, 1996.
27. Rosa Brunet, L., Beall, M., Dunne, D.W. and Pearce, E.J. Nitric oxide and the Th2 response combine to prevent severe hepatic damage during Schistosoma mansoni infection. J. Immunol. 163: 4976-4984, 1999.
28. Schlüter, D., Deckert, M., Hof, H. and Frei, K. Toxoplasma gondii infection of neurons induces neuronal cytokine and chemokine production, but gamma interferon- and tumor necrosis factor-stimulated neurons fail to inhibit the invasion and growth of T. gondii. Infect. Immun. 69: 7889-7893, 2001.
29. Sharghi, N., Schantz, P.M., Caramico, L., Ballas, K., Teague, B.A. and Hotez, P.J. Environmental exposure to Toxocara as a possible risk factor for asthma: A clinical-based case-control study. Clin. Infect. Dis. 32:111-116, 2001.
30. Soh, C.T. The distribution and persistence of hookworm larvae in the tissues of mice in relation to species and to route of inoculation. J. Parasitol. 44: 515-519, 1958.
31. Soulsby, E.J.L. Helmints, artropods and protozoa of domesticated animals. 7th ed. London, Bailliere-Tindall, 1982.
32. Sun, Y., Oberley, L.W. and Li, Y.A. Simple method for clinical assay of superoxide dismutase. Clin. Chem. 34: 497-500, 1988.
33. Vincent, J.L., Zhang, H., Szabo, C. and Preiser, J.C. Effects of nitric oxide in septic shock. Am. J. Resp. Crit. Care. 161: 1781-1785, 2000.
34. Viswambharan, H., Seebeck, T. and Yang, Z. Enhanced endothelial nitric oxide-synthase activity in mice infected with Trypanosoma brucei. Int. J. Parasitol. 33: 1099-1104, 2003.