-
1
-
-
0034050902
-
Systematic variation in gene expression patterns in human cancer cell lines
-
Ross DT, Scherf U, Eisen MBC et al. Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet 2000; 24: 227-35.
-
(2000)
Nat Genet
, vol.24
, pp. 227-235
-
-
Ross, D.T.1
Scherf, U.2
Eisen, M.B.C.3
-
2
-
-
0034088857
-
A gene expression database for the molecular pharmacology of cancer
-
Scherf U, Ross DT, Waltham M et al. A gene expression database for the molecular pharmacology of cancer. Nat Genet 2000; 24: 236-44.
-
(2000)
Nat Genet
, vol.24
, pp. 236-244
-
-
Scherf, U.1
Ross, D.T.2
Waltham, M.3
-
4
-
-
0037081081
-
Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs
-
Zembutsu H, Ohnishi Y, Tsunoda T et al. Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs. Cancer Res 2002; 62: 518-27.
-
(2002)
Cancer Res
, vol.62
, pp. 518-527
-
-
Zembutsu, H.1
Ohnishi, Y.2
Tsunoda, T.3
-
5
-
-
0036168343
-
An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines
-
Dan S, Tsunoda T, Kitahara O et al. An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Res 2002; 62: 1139-47.
-
(2002)
Cancer Res
, vol.62
, pp. 1139-1147
-
-
Dan, S.1
Tsunoda, T.2
Kitahara, O.3
-
6
-
-
24644482101
-
Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts
-
Takechi T, Okabe H, Ikeda K et al. Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts. Oncol Report 2005; 14: 33-9.
-
(2005)
Oncol Report
, vol.14
, pp. 33-39
-
-
Takechi, T.1
Okabe, H.2
Ikeda, K.3
-
7
-
-
33744539833
-
Gene expression analysis using human cancer xenografts to identify novel predictive marker genes for the efficacy of 5-fluorouracil-based drugs
-
Ooyama A, Takechi T, Toda E et al. Gene expression analysis using human cancer xenografts to identify novel predictive marker genes for the efficacy of 5-fluorouracil-based drugs. Cancer Sci 2006; 97: 510-22.
-
(2006)
Cancer Sci
, vol.97
, pp. 510-522
-
-
Ooyama, A.1
Takechi, T.2
Toda, E.3
-
8
-
-
0036057596
-
Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): A review
-
Malet-Martino M, Martino R. Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): A review. Oncologist 2002; 7: 288-323.
-
(2002)
Oncologist
, vol.7
, pp. 288-323
-
-
Malet-Martino, M.1
Martino, R.2
-
9
-
-
0031731668
-
Anticancer activity and toxicity of S-1, an oral combination of tegafur and two biochemical modulators, compared with continuous i.v. infusion of 5-fluorouracil
-
Fukushima M, Shimamoto Y, Kato T et al. Anticancer activity and toxicity of S-1, an oral combination of tegafur and two biochemical modulators, compared with continuous i.v. infusion of 5-fluorouracil. Anticancer Drugs 1998; 9: 817-23.
-
(1998)
Anticancer Drugs
, vol.9
, pp. 817-823
-
-
Fukushima, M.1
Shimamoto, Y.2
Kato, T.3
-
11
-
-
0034939638
-
Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells
-
Takechi T, Koizumi K, Tsujimoto H, Fukushima M. Screening of differentially expressed genes in 5-fluorouracil-resistant human gastrointestinal tumor cells. Jpn J Cancer Res 2001; 92: 696-703.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 696-703
-
-
Takechi, T.1
Koizumi, K.2
Tsujimoto, H.3
Fukushima, M.4
-
12
-
-
0141919448
-
Genomic instability and cancer
-
Charames GS, Bapat B. Genomic instability and cancer. Curr Mol Med 2003; 3: 589-96.
-
(2003)
Curr Mol Med
, vol.3
, pp. 589-596
-
-
Charames, G.S.1
Bapat, B.2
-
13
-
-
0026495364
-
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
-
Kallioniemi A, Kallioniemi OP, Sudar D et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 1992; 258: 818-21.
-
(1992)
Science
, vol.258
, pp. 818-821
-
-
Kallioniemi, A.1
Kallioniemi, O.P.2
Sudar, D.3
-
14
-
-
33645736791
-
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers
-
Gaasenbeek M, Howarth K, Rowan AJ et al. Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers. Cancer Res 2006; 7: 3471-9.
-
(2006)
Cancer Res
, vol.7
, pp. 3471-3479
-
-
Gaasenbeek, M.1
Howarth, K.2
Rowan, A.J.3
-
15
-
-
2342647468
-
High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines
-
Janne PA, Li C, Zhao X et al. High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene 2004; 15: 2716-26.
-
(2004)
Oncogene
, vol.15
, pp. 2716-2726
-
-
Janne, P.A.1
Li, C.2
Zhao, X.3
-
16
-
-
0034885982
-
Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo
-
Fukushima M, Fujioka A, Uchida J, Nakagawa F, Takechi T. Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo. Eur J Cancer 2001; 37: 1681-7.
-
(2001)
Eur J Cancer
, vol.37
, pp. 1681-1687
-
-
Fukushima, M.1
Fujioka, A.2
Uchida, J.3
Nakagawa, F.4
Takechi, T.5
-
17
-
-
16644397382
-
Antimetastatic and anticancer activity of S-1, a new oral dihydropyrimidine-dehydrogenase-inhibiting fluoropyrimidine, alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model
-
Nukatsuka M, Fujioka A, Nakagawa F et al. Antimetastatic and anticancer activity of S-1, a new oral dihydropyrimidine-dehydrogenase-inhibiting fluoropyrimidine, alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model. Int J Oncol 2004; 25: 1531-6.
-
(2004)
Int J Oncol
, vol.25
, pp. 1531-1536
-
-
Nukatsuka, M.1
Fujioka, A.2
Nakagawa, F.3
-
18
-
-
24644482101
-
Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts
-
Takechi T, Okabe H, Ikeda K et al. Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts. Oncol Rep 2005; 14: 33-9.
-
(2005)
Oncol Rep
, vol.14
, pp. 33-39
-
-
Takechi, T.1
Okabe, H.2
Ikeda, K.3
-
19
-
-
16744368637
-
Guidelines for the Welfare of Animals in Experimental Neoplasia (2nd edn)
-
UKCCCR Guidelines. United Kingdom Co-Ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (2nd edn). Br J Cancer 1998; 77: 1-10
-
UKCCCR Guidelines. United Kingdom Co-Ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (2nd edn). Br J Cancer 1998; 77: 1-10.
-
(1998)
Br J Cancer
, vol.77
, pp. 1-10
-
-
-
20
-
-
2342453338
-
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays
-
Zhao X, Li C, Paez JG et al. An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res 2004; 64: 3060-71.
-
(2004)
Cancer Res
, vol.64
, pp. 3060-3071
-
-
Zhao, X.1
Li, C.2
Paez, J.G.3
-
21
-
-
0034518362
-
Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
-
Ulrich CM, Bigler J, Velicer CM, Greene EA, Farin FM, Potter JD. Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 2000; 9: 1381-5.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 1381-1385
-
-
Ulrich, C.M.1
Bigler, J.2
Velicer, C.M.3
Greene, E.A.4
Farin, F.M.5
Potter, J.D.6
-
22
-
-
0020056302
-
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas
-
Spears CP, Shahinian AH, Moran RG, Heidelberger C, Corbett TH. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas. Cancer Res 1982; 42: 450-6.
-
(1982)
Cancer Res
, vol.42
, pp. 450-456
-
-
Spears, C.P.1
Shahinian, A.H.2
Moran, R.G.3
Heidelberger, C.4
Corbett, T.H.5
-
23
-
-
0028125957
-
ERBB2 (HER2/neu) oncogene is frequently amplified in squamous cell carcinoma of the uterine cervix
-
Mitra AB, Murty VV, Pratap M, Sodhani P, Chaganti RS. ERBB2 (HER2/neu) oncogene is frequently amplified in squamous cell carcinoma of the uterine cervix. Cancer Res 1994; 54: 637-9.
-
(1994)
Cancer Res
, vol.54
, pp. 637-639
-
-
Mitra, A.B.1
Murty, V.V.2
Pratap, M.3
Sodhani, P.4
Chaganti, R.S.5
-
24
-
-
0343444822
-
Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas
-
Escot C, Theillet C, Lidereau R et al. Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas. Proc Natl Acad Sci USA 1986; 83: 4834-8.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4834-4838
-
-
Escot, C.1
Theillet, C.2
Lidereau, R.3
-
25
-
-
0029091503
-
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
-
Cairns P, Polascik TJ, Eby Y et al. Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nat Genet 1995; 11: 210-12.
-
(1995)
Nat Genet
, vol.11
, pp. 210-212
-
-
Cairns, P.1
Polascik, T.J.2
Eby, Y.3
-
26
-
-
0037403254
-
Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells
-
Hidaka S, Yasutake T, Fukushima M et al. Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells. Eur J Cancer 2003; 39: 975-80.
-
(2003)
Eur J Cancer
, vol.39
, pp. 975-980
-
-
Hidaka, S.1
Yasutake, T.2
Fukushima, M.3
-
27
-
-
0035878867
-
Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors
-
Wang W, Marsh S, Cassidy J, McLeod HL. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors. Cancer Res 2001; 61: 5505-10.
-
(2001)
Cancer Res
, vol.61
, pp. 5505-5510
-
-
Wang, W.1
Marsh, S.2
Cassidy, J.3
McLeod, H.L.4
-
28
-
-
12144290775
-
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
-
Wang TL, Diaz LA Jr, Romans K et al. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. Proc Natl Acad Sci USA 2004; 101: 3089-94.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3089-3094
-
-
Wang, T.L.1
Diaz Jr., L.A.2
Romans, K.3
-
29
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995; 55: 1407-12.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
-
30
-
-
14444285483
-
p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival
-
Lenz HJ, Hayashi K, Salonga D et al. p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival. Clin Cancer Res 1998; 4: 1243-50.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1243-1250
-
-
Lenz, H.J.1
Hayashi, K.2
Salonga, D.3
-
31
-
-
33750317308
-
Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy
-
Brody JR, Hucl T, Gallmeier E, Winter JM, Kern SE, Murphy KM. Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy. Cancer Res 2006; 19: 9369-73.
-
(2006)
Cancer Res
, vol.19
, pp. 9369-9373
-
-
Brody, J.R.1
Hucl, T.2
Gallmeier, E.3
Winter, J.M.4
Kern, S.E.5
Murphy, K.M.6
-
33
-
-
0030747797
-
Transforming growth factor-β1 enhances the lethal effects of DNA-damaging agents in a human lung-cancer cell line
-
Raynal S, Nocentini S, Croisy A, Lawrence DA, Jullien P. Transforming growth factor-β1 enhances the lethal effects of DNA-damaging agents in a human lung-cancer cell line. Int J Cancer 1997; 2: 356-61.
-
(1997)
Int J Cancer
, vol.2
, pp. 356-361
-
-
Raynal, S.1
Nocentini, S.2
Croisy, A.3
Lawrence, D.A.4
Jullien, P.5
-
34
-
-
24344444413
-
SMAD4 levels and response to 5-fluorouracil in colorectal cancer
-
Alhopuro P, Alazzouzi H, Sammalkorpi H et al. SMAD4 levels and response to 5-fluorouracil in colorectal cancer. Clin Cancer Res 2005; 17: 6311-16.
-
(2005)
Clin Cancer Res
, vol.17
, pp. 6311-6316
-
-
Alhopuro, P.1
Alazzouzi, H.2
Sammalkorpi, H.3
-
35
-
-
0036739307
-
Midkine and pleiotrophin: Two related proteins involved in development, survival, inflammation and tumorigenesis
-
Muramatsu T. Midkine and pleiotrophin: Two related proteins involved in development, survival, inflammation and tumorigenesis. J Biochem (Tokyo) 2002; 3: 359-71.
-
(2002)
J Biochem (Tokyo)
, vol.3
, pp. 359-371
-
-
Muramatsu, T.1
-
36
-
-
1642576129
-
Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays
-
Kang HC, Kim IJ, Park JH et al. Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays. Clin Cancer Res 2004; 10: 272-84.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 272-284
-
-
Kang, H.C.1
Kim, I.J.2
Park, J.H.3
-
37
-
-
33845604643
-
Regulation of MDK expression in human cancer cells modulates sensitivities to various anticancer drugs: MDK overexpression confers to a multi-drug resistance
-
Kang HC, Kim IJ, Park JH et al. Regulation of MDK expression in human cancer cells modulates sensitivities to various anticancer drugs: MDK overexpression confers to a multi-drug resistance. Cancer Lett 2007; 1: 40-7.
-
(2007)
Cancer Lett
, vol.1
, pp. 40-47
-
-
Kang, H.C.1
Kim, I.J.2
Park, J.H.3
|