메뉴 건너뛰기




Volumn 364, Issue 2, 2007, Pages 431-440

Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes

Author keywords

Clades; Entry inhibitors; HIV 1; Microbicide; R5 X4 tropism

Indexed keywords

4 BENZOYL 1 [(4 METHOXY 1H PYRROLO[2,3 B]PYRIDIN 3 YL)OXOACETYL] 2 METHYLPIPERAZINE; AMD 3465; C52L; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CMPD 167; MICROBICIDE; UNCLASSIFIED DRUG;

EID: 34147186687     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.03.001     Document Type: Article
Times cited : (32)

References (46)
  • 2
    • 20944444788 scopus 로고    scopus 로고
    • Biologic and genetic characterization of a panel of 60 human immunodeficiency virus type 1 isolates, representing clades A, B, C, D, CRF01_AE, and CRF02_AG, for the development and assessment of candidate vaccines
    • Brown B.K., Darden J.M., Tovanabutra S., Oblander T., Frost J., Sanders-Buell E., de Souza M.S., Birx D.L., McCutchan F.E., and Polonis V.R. Biologic and genetic characterization of a panel of 60 human immunodeficiency virus type 1 isolates, representing clades A, B, C, D, CRF01_AE, and CRF02_AG, for the development and assessment of candidate vaccines. J. Virol. 79 10 (2005) 6089-6101
    • (2005) J. Virol. , vol.79 , Issue.10 , pp. 6089-6101
    • Brown, B.K.1    Darden, J.M.2    Tovanabutra, S.3    Oblander, T.4    Frost, J.5    Sanders-Buell, E.6    de Souza, M.S.7    Birx, D.L.8    McCutchan, F.E.9    Polonis, V.R.10
  • 4
    • 0034712874 scopus 로고    scopus 로고
    • Antibody and virus: binding and neutralization
    • Burton D.R., Williamson R.A., and Parren P.W. Antibody and virus: binding and neutralization. Virology 270 1 (2000) 1-3
    • (2000) Virology , vol.270 , Issue.1 , pp. 1-3
    • Burton, D.R.1    Williamson, R.A.2    Parren, P.W.3
  • 6
    • 0037379188 scopus 로고    scopus 로고
    • The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C
    • Cilliers T., Nhlapo J., Coetzer M., Orlovic D., Ketas T., Olson W.C., Moore J.P., Trkola A., and Morris L. The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C. J. Virol. 77 7 (2003) 4449-4456
    • (2003) J. Virol. , vol.77 , Issue.7 , pp. 4449-4456
    • Cilliers, T.1    Nhlapo, J.2    Coetzer, M.3    Orlovic, D.4    Ketas, T.5    Olson, W.C.6    Moore, J.P.7    Trkola, A.8    Morris, L.9
  • 7
    • 34147124231 scopus 로고    scopus 로고
    • Protein design of a bacterially expressed HIV-1 gp41 fusion inhibitor
    • [Electronic publication ahead of print]
    • Deng Y., Zheng Q., Ketas T.A., Moore J.P., and Lu M. Protein design of a bacterially expressed HIV-1 gp41 fusion inhibitor. Biochemistry (2007) [Electronic publication ahead of print]
    • (2007) Biochemistry
    • Deng, Y.1    Zheng, Q.2    Ketas, T.A.3    Moore, J.P.4    Lu, M.5
  • 8
    • 29744459673 scopus 로고    scopus 로고
    • Microbicides to prevent HIV transmission: overcoming obstacles to chemical barrier protection
    • Dhawan D., and Mayer K.H. Microbicides to prevent HIV transmission: overcoming obstacles to chemical barrier protection. J. Infect. Dis. 193 1 (2006) 36-44
    • (2006) J. Infect. Dis. , vol.193 , Issue.1 , pp. 36-44
    • Dhawan, D.1    Mayer, K.H.2
  • 11
    • 33644841528 scopus 로고    scopus 로고
    • How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked?
    • 181-185
    • Gupta K., and Klasse P.J. How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked?. PLoS Med. 3 2 (2006) e79 181-185
    • (2006) PLoS Med. , vol.3 , Issue.2
    • Gupta, K.1    Klasse, P.J.2
  • 12
    • 25844482131 scopus 로고    scopus 로고
    • Perils at mucosal front lines for HIV and SIV and their hosts
    • Haase A.T. Perils at mucosal front lines for HIV and SIV and their hosts. Nat. Rev., Immunol. 5 10 (2005) 783-792
    • (2005) Nat. Rev., Immunol. , vol.5 , Issue.10 , pp. 783-792
    • Haase, A.T.1
  • 14
  • 15
    • 0037321703 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells
    • Ketas T.J., Frank I., Klasse P.J., Sullivan B.M., Gardner J.P., Spenlehauer C., Nesin M., Olson W.C., Moore J.P., and Pope M. Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells. J. Virol. 77 4 (2003) 2762-2767
    • (2003) J. Virol. , vol.77 , Issue.4 , pp. 2762-2767
    • Ketas, T.J.1    Frank, I.2    Klasse, P.J.3    Sullivan, B.M.4    Gardner, J.P.5    Spenlehauer, C.6    Nesin, M.7    Olson, W.C.8    Moore, J.P.9    Pope, M.10
  • 17
    • 0036711665 scopus 로고    scopus 로고
    • Occupancy and mechanism in antibody-mediated neutralization of animal viruses
    • Klasse P.J., and Sattentau Q.J. Occupancy and mechanism in antibody-mediated neutralization of animal viruses. J. Gen. Virol. 83 9 (2002) 2091-2108
    • (2002) J. Gen. Virol. , vol.83 , Issue.9 , pp. 2091-2108
    • Klasse, P.J.1    Sattentau, Q.J.2
  • 18
    • 33748990336 scopus 로고    scopus 로고
    • Which topical microbicides for blocking HIV-1 transmission will work in the real world?
    • Klasse P.J., Shattock R.J., and Moore J.P. Which topical microbicides for blocking HIV-1 transmission will work in the real world?. PLoS Med. 3 9 (2006) 1501-1507
    • (2006) PLoS Med. , vol.3 , Issue.9 , pp. 1501-1507
    • Klasse, P.J.1    Shattock, R.J.2    Moore, J.P.3
  • 19
    • 33646342770 scopus 로고    scopus 로고
    • Microbicides and other topical strategies to prevent vaginal transmission of HIV
    • Lederman M.M., Offord R.E., and Hartley O. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nat. Immunol. Rev. 6 5 (2006) 371-382
    • (2006) Nat. Immunol. Rev. , vol.6 , Issue.5 , pp. 371-382
    • Lederman, M.M.1    Offord, R.E.2    Hartley, O.3
  • 20
    • 0242300205 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector
    • Lee M.T., Coburn G.A., McClure M.O., and Cullen B.R. Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector. J. Virol. 77 22 (2003) 11964-11972
    • (2003) J. Virol. , vol.77 , Issue.22 , pp. 11964-11972
    • Lee, M.T.1    Coburn, G.A.2    McClure, M.O.3    Cullen, B.R.4
  • 22
    • 33646891072 scopus 로고    scopus 로고
    • Cellulose acetate 1,2-benzenedicarboxylate inhibits infection by cell-free and cell-associated primary HIV-1 isolates
    • Lu H., Zhao Q., Wallace G., Liu S., He Y., Shattock R., Neurath A.R., and Jiang B.S. Cellulose acetate 1,2-benzenedicarboxylate inhibits infection by cell-free and cell-associated primary HIV-1 isolates. AIDS Res. Hum. Retroviruses 22 5 (2006) 411-418
    • (2006) AIDS Res. Hum. Retroviruses , vol.22 , Issue.5 , pp. 411-418
    • Lu, H.1    Zhao, Q.2    Wallace, G.3    Liu, S.4    He, Y.5    Shattock, R.6    Neurath, A.R.7    Jiang, B.S.8
  • 23
    • 33645046393 scopus 로고    scopus 로고
    • Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved?
    • Margolis L., and Shattock R. Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved?. Nat. Rev., Microbiol. 4 4 (2006) 312-317
    • (2006) Nat. Rev., Microbiol. , vol.4 , Issue.4 , pp. 312-317
    • Margolis, L.1    Shattock, R.2
  • 24
    • 23244467373 scopus 로고    scopus 로고
    • Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines
    • Mascola J.R., D'Souza P., Gilbert P., Hahn B.H., Haigwood N.L., Morris L., Petropoulos C.J., Polonis V.R., Sarzotti M., and Montefiori D.C. Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines. J. Virol. 79 16 (2005) 10103-10107
    • (2005) J. Virol. , vol.79 , Issue.16 , pp. 10103-10107
    • Mascola, J.R.1    D'Souza, P.2    Gilbert, P.3    Hahn, B.H.4    Haigwood, N.L.5    Morris, L.6    Petropoulos, C.J.7    Polonis, V.R.8    Sarzotti, M.9    Montefiori, D.C.10
  • 26
    • 33745621323 scopus 로고    scopus 로고
    • Global epidemiology of HIV
    • McCutchan F.E. Global epidemiology of HIV. J. Med. Virol. 78 Suppl. 1 (2006) S7-S12
    • (2006) J. Med. Virol. , vol.78 , Issue.SUPPL. 1
    • McCutchan, F.E.1
  • 28
    • 4043124699 scopus 로고    scopus 로고
    • Urgently needed: a filter for the HIV-1 vaccine pipeline
    • Moore J.P., and Burton D.R. Urgently needed: a filter for the HIV-1 vaccine pipeline. Nat. Med. 10 8 (2004) 769-771
    • (2004) Nat. Med. , vol.10 , Issue.8 , pp. 769-771
    • Moore, J.P.1    Burton, D.R.2
  • 29
    • 0742325043 scopus 로고    scopus 로고
    • The CCR5 and CXCR4 coreceptors - central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
    • Moore J.P., Kitchen S.G., Pugach P., and Zack J.A. The CCR5 and CXCR4 coreceptors - central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res. Hum. Retroviruses 20 1 (2004) 111-126
    • (2004) AIDS Res. Hum. Retroviruses , vol.20 , Issue.1 , pp. 111-126
    • Moore, J.P.1    Kitchen, S.G.2    Pugach, P.3    Zack, J.A.4
  • 32
    • 0030820369 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism
    • Pope M., Frankel S.S., Mascola J.R., Trkola A., Isdell F., Birx D.L., Burke D.S., Ho D.D., and Moore J.P. Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism. J. Virol. 71 10 (1997) 8001-8007
    • (1997) J. Virol. , vol.71 , Issue.10 , pp. 8001-8007
    • Pope, M.1    Frankel, S.S.2    Mascola, J.R.3    Trkola, A.4    Isdell, F.5    Birx, D.L.6    Burke, D.S.7    Ho, D.D.8    Moore, J.P.9
  • 34
    • 0345569681 scopus 로고    scopus 로고
    • Inhibiting sexual transmission of HIV-1 infection
    • Shattock R.J., and Moore J.P. Inhibiting sexual transmission of HIV-1 infection. Nat. Rev., Microbiol. 1 1 (2003) 25-34
    • (2003) Nat. Rev., Microbiol. , vol.1 , Issue.1 , pp. 25-34
    • Shattock, R.J.1    Moore, J.P.2
  • 35
    • 0036232981 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 antagonist, with other antiretroviral agents in vitro
    • Tremblay C.L., Giguel F., Kollmann C., Guan Y., Chou T.C., Baroudy B.M., and Hirsch M.S. Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 antagonist, with other antiretroviral agents in vitro. Antimicrob. Agents Chemother. 46 5 (2002) 1336-1339
    • (2002) Antimicrob. Agents Chemother. , vol.46 , Issue.5 , pp. 1336-1339
    • Tremblay, C.L.1    Giguel, F.2    Kollmann, C.3    Guan, Y.4    Chou, T.C.5    Baroudy, B.M.6    Hirsch, M.S.7
  • 36
    • 30444455633 scopus 로고    scopus 로고
    • TAK-652, a novel CCR5 inhibitor, has favourable drug interactions with other antiretrovirals in vitro
    • Tremblay C.L., Giguel F., Chou T.C., Dong H., Takashima K., and Hirsch M.S. TAK-652, a novel CCR5 inhibitor, has favourable drug interactions with other antiretrovirals in vitro. Antiviral Ther. 10 8 (2005) 967-968
    • (2005) Antiviral Ther. , vol.10 , Issue.8 , pp. 967-968
    • Tremblay, C.L.1    Giguel, F.2    Chou, T.C.3    Dong, H.4    Takashima, K.5    Hirsch, M.S.6
  • 37
    • 23044484979 scopus 로고    scopus 로고
    • TAK-220, a novel small-molecule CCR5 antagonist, has favorable anti-human immunodeficiency virus interactions with other antiretrovirals in vitro
    • Tremblay C.L., Giguel F., Guan Y., Chou T.C., Takashima K., and Hirsch M.S. TAK-220, a novel small-molecule CCR5 antagonist, has favorable anti-human immunodeficiency virus interactions with other antiretrovirals in vitro. Antimicrob. Agents Chemother. 49 8 (2005) 3483-3485
    • (2005) Antimicrob. Agents Chemother. , vol.49 , Issue.8 , pp. 3483-3485
    • Tremblay, C.L.1    Giguel, F.2    Guan, Y.3    Chou, T.C.4    Takashima, K.5    Hirsch, M.S.6
  • 38
    • 0031936306 scopus 로고    scopus 로고
    • Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage
    • Trkola A., Ketas T., Kewalramani V.N., Endorf F., Binley J.M., Katinger H., Robinson J., Littman D.R., and Moore J.P. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage. J. Virol. 72 3 (1998) 1876-1885
    • (1998) J. Virol. , vol.72 , Issue.3 , pp. 1876-1885
    • Trkola, A.1    Ketas, T.2    Kewalramani, V.N.3    Endorf, F.4    Binley, J.M.5    Katinger, H.6    Robinson, J.7    Littman, D.R.8    Moore, J.P.9
  • 41
    • 0035377540 scopus 로고    scopus 로고
    • Immune control of HIV: the obstacles of HLA and viral diversity
    • Walker B.D., and Korber B.T. Immune control of HIV: the obstacles of HLA and viral diversity. Nat. Immunol. 2 6 (2001) 473-475
    • (2001) Nat. Immunol. , vol.2 , Issue.6 , pp. 473-475
    • Walker, B.D.1    Korber, B.T.2
  • 42
    • 27644593773 scopus 로고    scopus 로고
    • Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: effects of viral diversity, target cell and receptor density
    • Willey S., Peters P.J., Sullivan W.M., Dorr P., Perros M., and Clapham P.R. Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: effects of viral diversity, target cell and receptor density. Antiviral Res. 68 2 (2005) 96-108
    • (2005) Antiviral Res. , vol.68 , Issue.2 , pp. 96-108
    • Willey, S.1    Peters, P.J.2    Sullivan, W.M.3    Dorr, P.4    Perros, M.5    Clapham, P.R.6
  • 44
    • 13744249284 scopus 로고    scopus 로고
    • Preferential use of CXCR4 by R5X4 human immunodeficiency virus type 1 isolates for infection of primary lymphocytes
    • Yi Y., Shaheen F., and Collman R.G. Preferential use of CXCR4 by R5X4 human immunodeficiency virus type 1 isolates for infection of primary lymphocytes. J. Virol. 79 3 (2005) 1480-1486
    • (2005) J. Virol. , vol.79 , Issue.3 , pp. 1480-1486
    • Yi, Y.1    Shaheen, F.2    Collman, R.G.3
  • 45
    • 0033008471 scopus 로고    scopus 로고
    • Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?
    • Zhang Y.J., and Moore J.P. Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?. J. Virol. 73 4 (1999) 3443-3448
    • (1999) J. Virol. , vol.73 , Issue.4 , pp. 3443-3448
    • Zhang, Y.J.1    Moore, J.P.2
  • 46
    • 0031710044 scopus 로고    scopus 로고
    • Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro
    • Zhang Y.J., Dragic T., Cao Y., Kostrikis L., Kwon D.S., Littman D.R., KewalRamani V.N., and Moore J.P. Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro. J. Virol. 72 11 (1998) 9337-9344
    • (1998) J. Virol. , vol.72 , Issue.11 , pp. 9337-9344
    • Zhang, Y.J.1    Dragic, T.2    Cao, Y.3    Kostrikis, L.4    Kwon, D.S.5    Littman, D.R.6    KewalRamani, V.N.7    Moore, J.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.