Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: Role of adenosine A1 and A2A receptors

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 4, 2007, Pages

  Montandon, Gaspard ^a   Kinkead, Richard ^a   Bairam, Aida ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Carbon dioxide chemosensitivity; Control of breathing; Hypercapnic ventilatory response; Plasticity; Ventilation

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR ANTAGONIST; CAFFEINE;

AIR CONDITIONING; ANIMAL EXPERIMENT; ANIMAL MODEL; APNEA; ARTICLE; CHEMOSENSITIVITY; CONTROLLED STUDY; FEMALE; HYPERCAPNIA; MALE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; RESPIRATORY FUNCTION;

ANIMALS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; HYPERCAPNIA; INJECTIONS, INTRAPERITONEAL; MALE; PLETHYSMOGRAPHY; PULMONARY VENTILATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; REST; TIME FACTORS; TRIAZINES; TRIAZOLES; XANTHINES;

EID: 34147186133     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00514.2006     Document Type: Article

References (68)

1. Al-Matary A, Kutbi I, Qurashi M, Khalil M, Alvaro R, Kwiatkowski K, Cates D, Rigatto H. Increased peripheral chemoreceptor activity may be critical in destabilizing breathing in neonates. Semin Perinatol 28: 264-272, 2004.
2. Bairam A, Boutroy MJ, Badonnel Y, Vert P. Theophylline versus caffeine: comparative effects in treatment of idiopathic apnea in the preterm infant. J Pediatr 110: 636-639, 1987.
3. Bairam A, Carroll JL. Neurotransmitters in carotid body development. Respir Physiol Neurobiol 149: 217-232, 2005.
4. Bhatt-Mehta V, Schumacher RE. Treatment of apnea of prematurity. Paediatr Drugs 5: 195-210, 2003.
5. Bodineau L, Cayetanot F, Sadani-Makki F, Bach V, Gros F, Lebleu A, Collin T, Frugiere A. Consequences of in utero caffeine exposure on respiratory output in normoxic and hypoxic conditions and related changes of Fos expression: a study on brainstem-spinal cord preparations isolated from newborn rats. Pediatr Res 53: 266-273, 2003.
6. Bodineau L, Saadani-Makki F, Jullien H, Frugiere A. Caffeine in the milk prevents respiratory disorders caused by in utero caffeine exposure in rats. Respir Physiol Neurobiol 150: 94-98, 2006.
7. Boulenger JP, Patel J, Post RM, Parma AM, Marangos PJ. Chronic caffeine consumption increases the number of brain adenosine receptors. Life Sci 32: 1135-1142, 1983.
8. 2A adenosine receptor antagonists. Curr Top Med Chem 3: 403-411, 2003.
9. 1 receptor distribution in the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats. J Neural Transm 111: 465-473, 2004.
10. Clancy B, Darlington RB, Finlay BL. Translating developmental time across mammalian species. Neuroscience 105: 7-17, 2001.
11. Coates EL, Li A, Nattie EE. Widespread sites of brain stem ventilatory chemoreceptors. J Appl Physiol 75: 5-14, 1993.
12. 2B adenosine receptors. J Neurochem 98: 616-628, 2006.
13. Drorbaugh JE, Fenn WO. A barometric method for measuring ventilation in newborn infants. Pediatrics 16: 81-87, 1955.
14. D'Urzo AD, Jhirad R, Jenne H, Avendano MA, Rubinstein I, D'Costa M, Goldstein RS. Effect of caffeine on ventilatory responses to hypercapnia, hypoxia, and exercise in humans. J Appl Physiol 68: 322-328, 1990.
15. 2A receptors. Br J Pharmacol 129: 1465-1473, 2000.
16. Enhorning G, van SS, Lundgren C, Vargas I. Whole-body plethysmography, does it measure tidal volume of small animals? Can J Physiol Pharmacol 76: 945-951, 1998.
17. Ezure K. Respiration-related afferents to parabrachial pontine regions. Respir Physiol Neurobiol 143: 167-175, 2004.
18. Feldman JL, Mitchell GS, Nattie EE. Breathing: rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci 26: 239-266, 2003.
19. Finer NN, Higgins R, Kattwinkel J, Martin RJ. Summary proceedings from the apnea-of-prematurity group. Pediatrics 117: S47-S51, 2006.
20. Finlayson K, Butcher SP, Sharkey J, Olverman HJ. Detection of adenosine receptor antagonists in rat brain using a modified radioreceptor assay. J Neurosci Methods 77: 135-142, 1997.
21. Fredholm BB, Battig K, Holmen J, Nehlig A, Zvartau EE. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51: 83-133, 1999.
22. Fredholm BB, Battig K, Holmen J, Nehlig A, Zvartau EE. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51: 83-133, 1999.
23. 1 receptor distribution in respiration-related nuclei of the rat brainstem. Auton Neurosci 126-127: 339-346, 2006.
24. Gleeson K, Zwillich CW. Adenosine infusion and periodic breathing during sleep. J Appl Physiol 72: 1004-1009, 1992.
25. Gray PA, Janczewski WA, Mellen N, McCrimmon DR, Feldman JL. Normal breathing requires preBotzinger complex neurokinin-1 receptor-expressing neurons. Nat Neurosci 4: 927-930, 2001.
26. 1 receptors in brain of rats. Neuropharmacology 30: 489-496, 1991.
27. 2A receptors. Neuropharmacology 46: 1008-1017, 2004.
28. Herlenius E, Aden U, Tang LQ, Lagercrantz H. Perinatal respiratory control and its modulation by adenosine and caffeine in the rat. Pediatr Res 51: 4-12, 2002.
29. Herlenius E, Lagercrantz H, Yamamoto Y. Adenosine modulates inspiratory neurons and the respiratory pattern in the brainstem of neonatal rats. Pediatr Res 42: 46-53, 1997.
30. Horne RS, Parslow PM, Harding R. Respiratory control and arousal in sleeping infants. Paediatr Respir Rev 5: 190-198, 2004.
31. 1, receptors mediate the arousal effect of caffeine. Nat Neurosci 8: 858-859, 2005.
32. Jacky JP. Barometric measurement of tidal volume: effects of pattern and nasal temperature. J Appl Physiol 49: 319-325, 1980.
33. 1 mRNA in mouse brain: effect of long-term caffeine treatment. Brain Res 762: 153-164, 1997.
34. 2A receptors in the motor effects of caffeine after its acute and chronic administration. Neuropsychopharmacology 28: 1281-1291, 2003.
35. 2 apneic threshold in newborn infants: possible relevance for periodic breathing and apnea. J Appl Physiol 98: 1171-1176, 2005.
36. Kinkead R, Dupenloup L, Valois N, Gulemetova R. Stress-induced attenuation of the hypercapnic ventilatory response in awake rats. J Appl Physiol 90: 1729-1735, 2001.
37. 2a receptor agonist in sheep. Am J Physiol Regul Integr Comp Physiol 274: R152-R159, 1998.
38. 2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs. Am J Physiol Regul Integr Comp Physiol 288: R1185-R1194, 2005.
39. 2A receptors modulate sleep state and breathing in fetal sheep. J Appl Physiol 91: 343-350, 2001.
40. Lagercrantz H, Yamamoto Y, Fredholm BB, Prabhakar NR, von EC. Adenosine analogues depress ventilation in rabbit neonates. Theophylline stimulation of respiration via adenosine receptors? Pediatr Res 18: 387-390, 1984.
41. Leevers AM, Simon PM, Dempsey JA. Apnea after normocapnic mechanical ventilation during NREM sleep. J Appl Physiol 77: 2079-2085, 1994.
42. Marcus CL. Sleep-disordered breathing in children. Am J Respir Crit Care Med 164: 16-30, 2001.
43. Martin RJ, Abu-Shaweesh JM. Control of breathing and neonatal apnea. Biol Neonate 87: 288-295, 2005.
44. Mayer CA, Haxhiu MA, Martin RJ, Wilson CG. Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats. J Appl Physiol 100: 91-97, 2006.
45. McQueen DS, Ribeiro JA. On the specificity and type of receptor involved in carotid body chemoreceptor activation by adenosine in the cat. Br J Pharmacol 80: 347-354, 1983.
46. Mendelson WB, Martin JV, Perlis M, Giesen H, Wagner R, Rapoport SI. Periodic cessation of respiratory effort during sleep in adult rats. Physiol Behav 43: 229-234, 1988.
47. Montandon G, Bairam A, Kinkead R. Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. Pediatr Res 59: 519-524, 2006.
48. Monteiro EC, Ribeiro JA. Ventilatory effects of adenosine mediated by carotid body chemoreceptors in the rat. Naunyn Schmiedebergs Arch Pharmacol 335: 143-148, 1987.
49. Monti D, Carley DW, Radulovacki M. Adenosine analogues modulate the incidence of sleep apneas in rats. Pharmacol Biochem Behav 51: 125-131, 1995.
50. 1 analogue, reduces sleep apneas in rats. Pharmacol Biochem Behav 53: 341-345, 1996.
51. Mortola JP, Dotta A. Effects of hypoxia and ambient temperature on gaseous metabolism of newborn rats. Am J Physiol Regul Integr Comp Physiol 263: R267-R272, 1992.
52. Mortola JP, Frappell PB. On the barometric method for measurements of ventilation, and its use in small animals. Can J Physiol Pharmacol 76: 937-944, 1998.
53. 2a adenosine receptor. Mol Pharmacol 48: 970-974, 1995.
54. Pianosi P, Grondin D, Desmond K, Coates AL, Aranda JV. Effect of caffeine on the ventilatory response to inhaled carbon dioxide. Respir Physiol 95: 311-320, 1994.
55. 2 receptors modulates the social recognition memory in reserpine-treated rats. Behav Pharmacol 16: 209-218, 2005.
56. 2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats. Behav Brain Res 159: 197-205, 2005.
57. 2A receptors. Neurosci Lett 376: 160-165, 2005.
58. 1 adenosine receptor expression in rats. Brain Res Dev Brain Res 89: 202-213, 1995.
59. 1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia. Brain Res 677: 193-203, 1995.
60. Rorke S, Holgate ST. Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. Am J Respir Med 1: 99-105, 2002.
61. 2A receptors in the rat central nervous system. J Comp Neurol 401: 163-186, 1998.
62. 1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure: a study on brainstem-spinal cord preparations isolated from newborn rats. Neuroscience 127: 505-518, 2004.
63. 2 receptor-mediated excitatory actions on the nervous system. Prog Neurobiol 48: 167-189, 1996.
64. 2a receptors in mouse brain. In Vivo 8: 1073-1078, 1994.
65. 1 receptors modulate the discharge activities of inspiratory and biphasic expiratory neurons in the medial region of nucleus retrofacialis of neonatal rat in vitro. Neurosci Lett 379: 27-31, 2005.
66. Wessberg P, Hedner J, Hedner T, Persson B, Jonason J. Adenosine mechanisms in the regulation of breathing in the rat. Eur J Pharmacol 106: 59-67, 1984.
67. Wong-Riley MT, Liu Q. Neurochemical development of brain stem nuclei involved in the control of respiration. Respir Physiol Neurobiol 149: 83-98, 2005.
68. 2A receptors are expressed by GABAergic neurons of medulla oblongata in developing rat. Brain Res 1071: 42-53, 2006.