High-level expression of secreted complex glycosylated recombinant human erythropoietin in the Physcomitrella Δ-fuc-t Δ-xyl-t mutant

Plant Biotechnology Journal

Volumn 5, Issue 3, 2007, Pages 389-401

  Weise, Andreas ^a   Altmann, Friedrich ^b   Rodriguez Franco, Marta ^a,e   Sjoberg, Eric R ^c   Bäumer, Wolfgang ^d   Launhardt, Heike ^a   Kietzmann, Manfred ^d   Gorr, Gilbert ^a  

^a Greenovation Biotech GmbH   (Germany)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^c VasGene Therapeutics Inc   (United States)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Erythropoietin; Glyco engineering; Moss; Recombinant protein production

Indexed keywords

COMPLEMENTARY DNA; RECOMBINANT ERYTHROPOIETIN;

ARTICLE; BIOREACTOR; BRYOPSIDA; GENETIC TRANSFORMATION; GENETICS; GLYCOSYLATION; HUMAN; METABOLISM; MUTATION; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTOPLAST; TEMPERATURE; TRANSGENIC PLANT; WESTERN BLOTTING;

BIOREACTORS; BLOTTING, WESTERN; BRYOPSIDA; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ERYTHROPOIETIN, RECOMBINANT; GLYCOSYLATION; HUMANS; MUTATION; PEPTIDE MAPPING; PLANTS, GENETICALLY MODIFIED; PROTOPLASTS; TEMPERATURE; TRANSFORMATION, GENETIC;

BRYOPHYTA; MAMMALIA; PHYSCOMITRELLA; PHYSCOMITRELLA PATENS;

EID: 34147185919     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2007.00248.x     Document Type: Article

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