메뉴 건너뛰기




Volumn 39, Issue 2, 2007, Pages 66-70

Oral phosphodiesterase-5 inhibitors: Effect of heme oxygenase inhibition on cGMP signalling in rat cavernous tissue

Author keywords

cGMP; Erectile dysfunction; Heme oxygenase; PDE inhibitors; Sildenafil; Tadalafil; Vardenafil

Indexed keywords

CYCLIC GMP; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; PROTOPORPHYRIN ZINC; SILDENAFIL; TADALAFIL; VARDENAFIL;

EID: 34147169896     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2007.00765.x     Document Type: Article
Times cited : (18)

References (32)
  • 2
    • 0022212903 scopus 로고
    • Heme metabolism and erythropoiesis in abnormal iron states. Role of aminolevulinic acid synthase and heme oxygenase
    • Abraham NG, Lutton JD, Levere RD (1985) Heme metabolism and erythropoiesis in abnormal iron states. Role of aminolevulinic acid synthase and heme oxygenase. Exp Haematol 13:833-843.
    • (1985) Exp Haematol , vol.13 , pp. 833-843
    • Abraham, N.G.1    Lutton, J.D.2    Levere, R.D.3
  • 3
    • 0031978604 scopus 로고    scopus 로고
    • Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosum
    • Bloch W, Klotz T, Sedlaczek P, Zumbe J, Engelmann U, Addicks K (1998) Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosum. Urol Res 26:129-135.
    • (1998) Urol Res , vol.26 , pp. 129-135
    • Bloch, W.1    Klotz, T.2    Sedlaczek, P.3    Zumbe, J.4    Engelmann, U.5    Addicks, K.6
  • 4
    • 3042574999 scopus 로고    scopus 로고
    • Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation
    • Blount MA, Beasley A, Zoraghi R, Sekhar KR, Bessay EP, Francis SH, Corbin JD (2004) Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation. Mol Pharmacol 66:144-152.
    • (2004) Mol Pharmacol , vol.66 , pp. 144-152
    • Blount, M.A.1    Beasley, A.2    Zoraghi, R.3    Sekhar, K.R.4    Bessay, E.P.5    Francis, S.H.6    Corbin, J.D.7
  • 5
    • 0034596874 scopus 로고    scopus 로고
    • Carbon monoxide generated by heme oxygenase-1 suppresses endothelial cell apoptosis
    • Brouard S, Otterbein LE, Anrarther J (2000) Carbon monoxide generated by heme oxygenase-1 suppresses endothelial cell apoptosis. J Exp Med 192:1015-1026.
    • (2000) J Exp Med , vol.192 , pp. 1015-1026
    • Brouard, S.1    Otterbein, L.E.2    Anrarther, J.3
  • 6
    • 0036728432 scopus 로고    scopus 로고
    • Nitric oxide regulation of penile erection: Biology and therapeutic implications
    • Burnett AL (2002) Nitric oxide regulation of penile erection: biology and therapeutic implications. J Androl 23:S20-S26.
    • (2002) J Androl , vol.23
    • Burnett, A.L.1
  • 7
    • 3343009056 scopus 로고    scopus 로고
    • Comparison of efficacy and safety of phosphodiesterase type 5 inhibitors in the treatment of erectile dysfunction
    • Chen Q, Wang N, Yao F, Lu X (2004) Comparison of efficacy and safety of phosphodiesterase type 5 inhibitors in the treatment of erectile dysfunction. Zhonghua Nan Ke Xue 10:302-304.
    • (2004) Zhonghua Nan Ke Xue , vol.10 , pp. 302-304
    • Chen, Q.1    Wang, N.2    Yao, F.3    Lu, X.4
  • 9
    • 0038745911 scopus 로고    scopus 로고
    • Heme oxygenase-1 in growth control and its clinical application to vascular disease
    • Durante W (2003) Heme oxygenase-1 in growth control and its clinical application to vascular disease. J Cell Physiol 195:373-382.
    • (2003) J Cell Physiol , vol.195 , pp. 373-382
    • Durante, W.1
  • 10
    • 0032757252 scopus 로고    scopus 로고
    • The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis
    • Foresti R, Motterlini R (1999) The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis. Free Radic Res 31:459-475.
    • (1999) Free Radic Res , vol.31 , pp. 459-475
    • Foresti, R.1    Motterlini, R.2
  • 11
    • 5444234287 scopus 로고    scopus 로고
    • Neural control of erection
    • Giuliano F, Rampin O (2004) Neural control of erection. Physiol Behav 83:189-201.
    • (2004) Physiol Behav , vol.83 , pp. 189-201
    • Giuliano, F.1    Rampin, O.2
  • 14
    • 0029990994 scopus 로고    scopus 로고
    • Carbon monoxide: An endogenous modulator of the nitric oxide-cGMP signaling system
    • Ingi T, Cheng J, Ronnett GV (1996) Carbon monoxide: an endogenous modulator of the nitric oxide-cGMP signaling system. Neuron 16:835-842.
    • (1996) Neuron , vol.16 , pp. 835-842
    • Ingi, T.1    Cheng, J.2    Ronnett, G.V.3
  • 15
    • 0032925845 scopus 로고    scopus 로고
    • Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb
    • Liu HJ, Mount DB, Nasjletti A, Wang WH (1999) Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb. J Clin Invest 103:963-970.
    • (1999) J Clin Invest , vol.103 , pp. 963-970
    • Liu, H.J.1    Mount, D.B.2    Nasjletti, A.3    Wang, W.H.4
  • 16
    • 4544272023 scopus 로고    scopus 로고
    • The heme oxygenase system: Past, present, and future
    • Maines MD (2004) The heme oxygenase system: past, present, and future. Antioxid Redox Signal 6:797-801.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 797-801
    • Maines, M.D.1
  • 17
    • 0038206465 scopus 로고    scopus 로고
    • Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP
    • Mingone CJ, Gupte SA, Quan S, Abraham NG, Wolin MS (2003) Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP. Exp Biol Med 228:535-539.
    • (2003) Exp Biol Med , vol.228 , pp. 535-539
    • Mingone, C.J.1    Gupte, S.A.2    Quan, S.3    Abraham, N.G.4    Wolin, M.S.5
  • 18
    • 0036227586 scopus 로고    scopus 로고
    • Nitric oxide independent activation of guanylate cyclase by YC-1 causes erectile responses in the rat
    • Mizusawa H, Hedlund P, Brioni JD, Sullivan JP, Andersson KE (2002) Nitric oxide independent activation of guanylate cyclase by YC-1 causes erectile responses in the rat. J Urol 167:2276-2281.
    • (2002) J Urol , vol.167 , pp. 2276-2281
    • Mizusawa, H.1    Hedlund, P.2    Brioni, J.D.3    Sullivan, J.P.4    Andersson, K.E.5
  • 19
    • 0141707960 scopus 로고    scopus 로고
    • Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1
    • Morse D, Pischke SE, Zhou Z (2003) Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J Biol Chem 278:36993-36998.
    • (2003) J Biol Chem , vol.278 , pp. 36993-36998
    • Morse, D.1    Pischke, S.E.2    Zhou, Z.3
  • 20
  • 21
    • 19944431852 scopus 로고    scopus 로고
    • Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both
    • Nakao A, Neto JS, Kannos S (2005) Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant 5:282-291.
    • (2005) Am J Transplant , vol.5 , pp. 282-291
    • Nakao, A.1    Neto, J.S.2    Kannos, S.3
  • 23
    • 0028958381 scopus 로고
    • Nitric oxide and cyclic GMP formation following relaxant nerve stimulation in isolated human corpus cavernosum
    • Pickard RS, Powell PH, Zar MA (1995) Nitric oxide and cyclic GMP formation following relaxant nerve stimulation in isolated human corpus cavernosum. Br J Urol 75:516-522.
    • (1995) Br J Urol , vol.75 , pp. 516-522
    • Pickard, R.S.1    Powell, P.H.2    Zar, M.A.3
  • 24
    • 17444408506 scopus 로고    scopus 로고
    • Efficacy and tolerability of vardenafil within the time window of 6 h after administration and beyond. Results of a clinical study carried out in 233 urological offices
    • Porst H, Lunglmayr G (2005) Efficacy and tolerability of vardenafil within the time window of 6 h after administration and beyond. Results of a clinical study carried out in 233 urological offices. MMW Fortschr Med 147 (Suppl. 1): 27-32.
    • (2005) MMW Fortschr Med , vol.147 , Issue.SUPPL. 1 , pp. 27-32
    • Porst, H.1    Lunglmayr, G.2
  • 25
    • 0028015605 scopus 로고
    • Carbon monoxide stimulates a potassium selective current in rabbit corneal epithelial cells
    • Rich A, Farrugia G, Rae JL (1994) Carbon monoxide stimulates a potassium selective current in rabbit corneal epithelial cells. Am J Physiol 267 (1 Pt 1): C435-C442.
    • (1994) Am J Physiol , vol.267 , Issue.1 PART 1
    • Rich, A.1    Farrugia, G.2    Rae, J.L.3
  • 26
    • 27744492554 scopus 로고    scopus 로고
    • Therapeutic applications of carbon monoxide-releasing molecules
    • Roberto M, Brian EM, Roberta F (2005) Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Invest Drugs 14:1305-1318.
    • (2005) Expert Opin Invest Drugs , vol.14 , pp. 1305-1318
    • Roberto, M.1    Brian, E.M.2    Roberta, F.3
  • 27
    • 2542461143 scopus 로고    scopus 로고
    • Carbon monoxide: To boldly go where NO has gone before
    • Ryter SW, Morse D, Choi AM (2004) Carbon monoxide: to boldly go where NO has gone before. Sci STKE 20:RE6.
    • (2004) Sci STKE , vol.20
    • Ryter, S.W.1    Morse, D.2    Choi, A.M.3
  • 28
    • 0031767014 scopus 로고    scopus 로고
    • Carbon monoxide is the major contributor to the regulation of vascular tone in aortas expressing high levels of heme oxygenase-1
    • Sammut IA, Foresti R, Clark JE, Exon DJ, Vesely MJJ, Sarathchandra P, Green CJ (1998) Carbon monoxide is the major contributor to the regulation of vascular tone in aortas expressing high levels of heme oxygenase-1. Br J Pharmacol 125:1437-1444.
    • (1998) Br J Pharmacol , vol.125 , pp. 1437-1444
    • Sammut, I.A.1    Foresti, R.2    Clark, J.E.3    Exon, D.J.4    Vesely, M.J.J.5    Sarathchandra, P.6    Green, C.J.7
  • 29
    • 34147157578 scopus 로고    scopus 로고
    • The effects of phosphodiesterase-5 inhibitor use on different organ systems
    • Schwarz ER, Kapur V, Rodriquez J, Rastogi S, Rosanio S (2006) The effects of phosphodiesterase-5 inhibitor use on different organ systems. Int J Impot Res 21:135-140.
    • (2006) Int J Impot Res , vol.21 , pp. 135-140
    • Schwarz, E.R.1    Kapur, V.2    Rodriquez, J.3    Rastogi, S.4    Rosanio, S.5
  • 30
    • 0031010733 scopus 로고    scopus 로고
    • Carbon monoxide-induced vasorelaxation and the underlying mechanisms
    • Wang R, Wang Z, Wu L (1997) Carbon monoxide-induced vasorelaxation and the underlying mechanisms. Br J Pharmacol 121:927-934.
    • (1997) Br J Pharmacol , vol.121 , pp. 927-934
    • Wang, R.1    Wang, Z.2    Wu, L.3
  • 31
    • 0037462754 scopus 로고    scopus 로고
    • Interaction of nitric oxide with human heme oxygenase-1
    • Wang J, Lu S, Moenne P, Montellano OR (2003) Interaction of nitric oxide with human heme oxygenase-1. J Biol Chem 278:2341-2347.
    • (2003) J Biol Chem , vol.278 , pp. 2341-2347
    • Wang, J.1    Lu, S.2    Moenne, P.3    Montellano, O.R.4
  • 32
    • 33746154470 scopus 로고    scopus 로고
    • Comparison of phosphodiesterase type 5 (PDE5) inhibitors
    • Wright PJ (2006) Comparison of phosphodiesterase type 5 (PDE5) inhibitors. Int J Clin Pract 60:967-975.
    • (2006) Int J Clin Pract , vol.60 , pp. 967-975
    • Wright, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.