Characterization of 5-HT3 receptor mutations identified in schizophrenic patients

Journal of Molecular Neuroscience

Volumn 30, Issue 3, 2006, Pages 273-281

  Thompson, Andrew J ^a   Sullivan, Nora L ^b   Lummis, Sarah C R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

5 HT3 receptor; Binding site; Cys loop receptor; Intracellular loop; Intracellular mutation; Ligand gated ion channel; M3 M4; Schizophrenia; Serotonin receptor; Whole cell patch clamp

Indexed keywords

GRANISETRON; SEROTONIN 3 RECEPTOR; TRITIUM; RECOMBINANT PROTEIN; SEROTONIN;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; PATCH CLAMP; PROTEIN EXPRESSION; RADIOASSAY; SCHIZOPHRENIA; WHOLE CELL; WILD TYPE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ELECTROPHYSIOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CONSERVED SEQUENCE; ELECTROPHYSIOLOGY; HUMANS; KINETICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; RECEPTORS, SEROTONIN, 5-HT3; RECOMBINANT PROTEINS; SCHIZOPHRENIA; SEQUENCE ALIGNMENT; SEROTONIN;

EID: 34147136600     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:30:3:273     Document Type: Article

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