Pharmacological and electrophysiological properties of the naturally occurring Pro391 Arg variant of the human 5-HT3A receptor

Pharmacogenetics

Volumn 14, Issue 3, 2004, Pages 165-172

  Kurzwelly, Delia ^a   Barann, Martin ^a,b   Kostanian, Arevat ^a   Combrink, Sandra ^a   Bönisch, Heinz ^a   Göthert, Manfred ^a   Brüss, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

3H GR65630 binding; HEK293 cells; Human 5 HT3A receptor (Pro391 Arg) h5 Ht3A receptor; Patch clamp studies; Serotonin receptor

Indexed keywords

3 (5 METHYL 1H IMIDAZOL 4 YL) 1 (1 METHYL 1H INDOL 3 YL) 1 PROPANONE; ARGININE; AZASETRON; PROLINE; QUIPAZINE; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN 3A RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; ELECTROPHYSIOLOGY; EMBRYO; EVOKED RESPONSE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KINETICS; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR DENSITY; WILD TYPE;

BINDING, COMPETITIVE; CELL MEMBRANE; ELECTROPHYSIOLOGY; HUMANS; IMIDAZOLES; INDOLES; ION CHANNELS; KIDNEY; KINETICS; LEUCINE; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROLINE; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; VARIATION (GENETICS);

EMESIS;

EID: 1642378870     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200403000-00004     Document Type: Article

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