Developmental gene expression of antimicrobial peptide Protegrin-1 and effect of weaning on gene regulation of Protegrin-1 in piglets

Journal of Animal and Feed Sciences

Volumn 16, Issue 1, 2007, Pages 86-95

  Han, F F ^a   Wang, Y Z ^a   Feng, J ^a   Guo, J ^a   Xu, Z R ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Day age; Gene expression; Piglet; Protegrin 1; Reverse transcription polymerase chain reaction (RT PCR); Weaning

Indexed keywords

EID: 34047260092     PISSN: 12301388     EISSN: None     Source Type: Journal    
DOI: 10.22358/jafs/66729/2007     Document Type: Article

References (27)

1. Boman H.G., 1998. Gene-encoded peptide antibiotics and the concept of innate immunity: an update review. Scand. J. Immunol. 48, 15-25
2. Brown D.C., Maxwell C.V., Davis M.E., Erf G.F., Singh S., 2002. Effects of segregated early weaning on systemic and enteric T lymphocyte subpopulations in pigs. J. Anim. Sci. 80, Suppl. 1, 30-31
3. Duncan D.B., 1955. Multiple range and multiple F tests. Biometrics 11, 1-42
4. Gallo R.L., Kim M., Kozak C.A., Zanetti M., Merluzzi L., Gennaro R., 1997. Identification of CRAMP, a Cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. J. Biol. Chem. 272, 13088-13093
5. Gennaro R., Zanetti M., 2000. Structural features and biological activities of the cathelicidin-derived antimicrobial peptides. Biopolymers 55, 31-49
6. Gudmundsson G.H., Magnusson K.P., Chowdhary B.P., Johansson M., Andersson L., Boman H.G., 1995. Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. Proc. Nat. Acad. Sci. USA. 92, 7085-7089
7. Harwig S.S., Kokryakov V.N., Swiderek K.M., Aleshina G.M., Zhao C., LehrerR.I., 1995. Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes. FEBS Lett. 362, 65-69
8. Hicks T.A., McGlone J.J., Whisnant C.S., Kattesh H.G., Norman R.L., 1998. Behavioral, endocrine, immune, and performance measures for pigs exposed to acute stress. J. Anim. Sci. 76, 474-483
9. Hohenshell L.M., Cunnick I.E., Ford S.P., Kattesh H.G., Zimmerman D.R., Wilson M.E., Matteri R.L., Carroll J.A., Lay Jr. D.C., 2000. Few differences found between early and late weaned pigs raised in the same environment. J. Anim. Sci. 78, 38-49
10. Kokryakov V.N., Harwig S.S., Panyutich E.A., Shevchenko A.A., Aleshina G.M., Shamova O.V., 1993. Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett. 327, 231-236
11. Lehrer R.I., Ganz T., 1999. Antimicrobial peptides in mammalian and insect host defense. Curr. Opin. Immunol. 11, 23-27
12. Marone M., Mozzetti S., Ritis D.D., Pierelli L., Scambia G., 2001. Semiquantitative RT-PCR analysis to assess the expression levels of multiple transcripts from the same sample. Biol. Proced. Online. 3(1), 19-25
13. Metz J.H.M., Gonyou H.W., 1990. Effect of age and housing conditions on the behavioural and haemolytic reaction of piglets to weaning. Appl. Anim. Behav. Sci. 27, 299-309
14. Moore C., 1996. Managing early weaned pigs. West. Hog J. 17 (3), 4-7
15. Ramanathan B., Davis E.G., Ross C.R., Blecha F., 2002. Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity. Microbes Infect Mar. 4, 361-372
16. Ridge J.P., Ephraim J., Matzinger P., 1996. Neonatal tolerance revisited: turning on newborn T cells with dendritic cells. Science 271, 1723-1726
17. Scocchi M., Bontempo D., Boscolo S., Tomasinsig L., Giulotto E., Zaneetti M., 1999. Novel cathelicidins in horse leukocytes. FEBS Lett. 457, 459-464
18. Storice P., Zanetti M.A., 1993. cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39. Biochem. Biophys. Res. Commun. 196, 1058-1065
19. Wang Y.Z., Liu G.F., Chu X.N., Han F.F., 2004a. PCR amplication, cloning and sequencing of protegrin-1 gene of porcine antibacterial peptide. J. Zhejiang Univ. 30, 336-339
20. Wang Y.Z., Xu Z.R., Lin W.X., Huang H.Q., Wang Z.Q., 2004b. Developmental gene expression of antimicrobial peptide PR-39 and effect of zinc oxide on gene regulation of PR-39 in piglets. Asian-Austr. J. Anim. Sci. 17, 1635-1640
21. Wu H., Zhang G.L., Minton J.E., Ross C.R., Blecha F., 2000. Regulation of cathelicidin gene expression: Induction by lipopolysaccharide, Interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection. Infec. Immunity 68, 5552-5558
22. Wu H., Zhang G.L., Ross C.R., Blecha F., 1999. Cathelicidin gene expression in porcine tissues: Roles in ontogeny and tissue specificity. Infec. Immunity 67, 439-442
23. Yasin B., Lehrer R.I., Harwig S.S., Wagar E.A., 1996. Susceptibility of Chlamydia trachomatis to protegrins and defensins. Infec. Immunity 64, 4863-4866
24. Zanetti M., Gennaro R., Romeo D., 1995. Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett. 374, 1-5
25. Zanetti M., Litteri L., Gennaro R., Horstmann H., Romeo D., 1990. Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules. J. Cell Biol. 111, 1363-1371
26. Zanetti M., Storici P., Tossi A., Scocchi M., Gennaro R., 1994. Molecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells. J. Biol. Chem. 269, 7855-7858
27. Zhang G., Ross C.R., Blecha F., 2000. Porcine antimicrobial peptides: new prospects for ancient molecules of host defense. Vet. Res. 31, 277-296