Intravenous mononuclear marrow cells reverse neuropathic pain from experimental mononeuropathy

Anesthesia and Analgesia

Volumn 104, Issue 4, 2007, Pages 944-948

  Klass, Markus ^a   Gavrikov, Vitaliy ^a   Drury, Danielle ^a   Stewart, Bethany ^a   Hunter, Stephen ^a   Denson, Donald D ^a   Hord, Allen ^a   Csete, Marie ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CELL ISOLATION; CHRONIC DISEASE; CONTROLLED STUDY; MALE; MONONEUROPATHY; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE;

ANIMALS; BEHAVIOR, ANIMAL; BONE MARROW TRANSPLANTATION; DISEASE MODELS, ANIMAL; HEAT; HYPERALGESIA; LIGATION; MALE; NEURALGIA; PAIN MEASUREMENT; PAIN THRESHOLD; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SCIATIC NERVE; SCIATIC NEUROPATHY; STEM CELL TRANSPLANTATION; TIME FACTORS; TOUCH;

EID: 34047254693     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000258021.03211.d0     Document Type: Article

References (18)

1. Lindvall O, Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 2006;441:1094-6.
2. English D, Klasko SK, Sanberg P. Elusive mechanism of "stem cell"-mediated repair of cerebral damage. Exp Neurol 2006;199:10-5.
3. Lindvall O, Kokaia Z, Martinez-Serrano A. Stem cell therapy for human neurodegenerative disorders - how to make it work. Nature Med 2004;10:S42-50.
4. Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988;33:77-88.
5. Klass M, Hord A, Wilcox M, et al. A role for endothelin in neuropathic pain after chronic constriction injury. Anesth Analg 2005;101:1757-62.
6. Hord AH, Denson DD, Chalfoun AG, Azevedo MI. The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy. Anesth Analg 2003;96:1700-6.
7. Guay DR. Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. Am J Geriatric Pharmacother 2003;1:18-37.
8. Atli A, Dogra S. Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study. Pain Med 2005;6:225-34.
9. Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SCF-1. Nat Med 2004;10:858-64.
10. Muller F-J, Snyder EY, Loring FJ. Gene therapy: can neural stem cells deliver? Nat Rev Neurosci 2006;7:75-84.
11. Thrasivoulou C, Soubeyre V, Ridha H, et al. Reactive oxygen species, dietary restriction and neurotrophic factors in age-related loss of myenteric neurons. Aging Cell 2006;5:247-257.
12. Bennett GJ. A neuroimmune interaction in painful peripheral neuropathy. Clin J Pain 2000;16:S139-43.
13. Kajander KC, Pollock CH, Berg H. Evaluation of hindpaw position in rats during chronic constriction injury (CCI) produced with different suture materials. Somatosens Mot Res 1996;13:95-101.
14. Pezet S, Krzyzanowska A, Wong LF, et al. Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF. Mol Ther 2006;13:1101-9.
15. Campana WM, Li X, Shubayev VI, et al. Erythropoietin reduces Schwann cell TNF-alpha, Wallerian degeneration and pain related behaviors after peripheral nerve injury. Eur J Neurosci 2006;23:617-26.
16. Moalem G, Xu K, Yu L. T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats. Neuroscience 2004;129:767-77.
17. Kanematsu A, Yamamoto X, Iwai-Kanai E, et al. Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells. Am J Pathol 2005;166:565-73.
18. Terashima T, Kojima H, Fumimiya M, et al. The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy. Proc Natl Acad Sci USA 2005;102:12525-30.