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Volumn 27, Issue 4, 2007, Pages 538-547

Endogenous opioids modulate hepatocyte apoptosis in a rat model of chronic cholestasis: The role of oxidative stress

Author keywords

Antioxidant enzyme; Apoptosis; Cholestasis; Glutathione; Liver injury; Naltrexone; Opioid receptors

Indexed keywords

ANTIOXIDANT; ENDORPHIN; ENZYME; GLUTATHIONE; NALTREXONE; OPIATE ANTAGONIST; OXIDIZING AGENT; SODIUM CHLORIDE;

EID: 34047192771     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2007.01457.x     Document Type: Article
Times cited : (19)

References (57)
  • 1
    • 0036080253 scopus 로고    scopus 로고
    • Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease
    • Guicciardi ME, Gores GJ. Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease. Dig Liver Dis 2002; 34: 387-92.
    • (2002) Dig Liver Dis , vol.34 , pp. 387-392
    • Guicciardi, M.E.1    Gores, G.J.2
  • 3
    • 0026068929 scopus 로고
    • Liver transplantation in pediatrics: Indications, contraindications, and pretransplant management
    • Whitington PF, Balistreri WF. Liver transplantation in pediatrics: indications, contraindications, and pretransplant management. J Pediatr 1991; 118: 169-77.
    • (1991) J Pediatr , vol.118 , pp. 169-177
    • Whitington, P.F.1    Balistreri, W.F.2
  • 4
    • 0034060334 scopus 로고    scopus 로고
    • Apoptosis and liver disease
    • Rust C, Gores GJ. Apoptosis and liver disease. Am J Med 2000; 108: 567-74.
    • (2000) Am J Med , vol.108 , pp. 567-574
    • Rust, C.1    Gores, G.J.2
  • 5
    • 0029012444 scopus 로고
    • Apoptosis and hepatobiliary disease
    • Patel T, Gores GJ. Apoptosis and hepatobiliary disease. Hepatology 1995; 21: 1725-41.
    • (1995) Hepatology , vol.21 , pp. 1725-1741
    • Patel, T.1    Gores, G.J.2
  • 6
    • 0036775096 scopus 로고    scopus 로고
    • Induction and regulation of hepatocyte apoptosis by oxidative stress
    • Czaja MJ. Induction and regulation of hepatocyte apoptosis by oxidative stress. Antioxid Redox Signal 2002; 4: 759-67.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 759-767
    • Czaja, M.J.1
  • 7
    • 0033756534 scopus 로고    scopus 로고
    • Evidence of a systemic phenomenon for oxidative stress in cholestatic liver disease
    • Ljubuncic P, Tanne Z, Bomzon A. Evidence of a systemic phenomenon for oxidative stress in cholestatic liver disease. Gut 2000; 47: 710-6.
    • (2000) Gut , vol.47 , pp. 710-716
    • Ljubuncic, P.1    Tanne, Z.2    Bomzon, A.3
  • 8
    • 0032876326 scopus 로고    scopus 로고
    • Role of glutathione, lipid peroxidation and antioxidants on acute bile-duct obstruction in the rat
    • Baron V, Muriel P. Role of glutathione, lipid peroxidation and antioxidants on acute bile-duct obstruction in the rat. Biochim Biophys Acta 1999; 1472: 173-80.
    • (1999) Biochim Biophys Acta , vol.1472 , pp. 173-180
    • Baron, V.1    Muriel, P.2
  • 9
    • 0030660351 scopus 로고    scopus 로고
    • Bile acids, oxidative stress, and renal function in biliary obstruction
    • Bomzon A, Holt S, Moore K. Bile acids, oxidative stress, and renal function in biliary obstruction. Semin Nephrol 1997; 17: 549-62.
    • (1997) Semin Nephrol , vol.17 , pp. 549-562
    • Bomzon, A.1    Holt, S.2    Moore, K.3
  • 10
    • 0027175761 scopus 로고
    • Changes of lipid peroxide levels in blood and liver tissue of patients with obstructive jaundice
    • Tsai LY, Lee KT, Tsai SM, Lee SC, Yu HS. Changes of lipid peroxide levels in blood and liver tissue of patients with obstructive jaundice. Clin Chim Acta 1993; 215: 41-50.
    • (1993) Clin Chim Acta , vol.215 , pp. 41-50
    • Tsai, L.Y.1    Lee, K.T.2    Tsai, S.M.3    Lee, S.C.4    Yu, H.S.5
  • 12
    • 0029859359 scopus 로고    scopus 로고
    • Hepatic concentrations of proenkephalin-derived opioids are increased in a rat model of cholestasis
    • Bergasa NV, Vergalla J, Swain MG, Jones EA. Hepatic concentrations of proenkephalin-derived opioids are increased in a rat model of cholestasis. Liver 1996; 16: 298-302.
    • (1996) Liver , vol.16 , pp. 298-302
    • Bergasa, N.V.1    Vergalla, J.2    Swain, M.G.3    Jones, E.A.4
  • 13
    • 0028167781 scopus 로고
    • Alterations in hypothalamic mu-opiate receptor-mediated responses but not methionine enkephalin or proenkephalin messenger RNA levels in rats with acute cholestasis
    • Swain MG. Alterations in hypothalamic mu-opiate receptor-mediated responses but not methionine enkephalin or proenkephalin messenger RNA levels in rats with acute cholestasis. Hepatology 1994; 20: 700-5.
    • (1994) Hepatology , vol.20 , pp. 700-705
    • Swain, M.G.1
  • 14
    • 0028204163 scopus 로고
    • Adrenal secretion of BAM-22P, a potent opioid peptide, is enhanced in rats with acute cholestasis
    • Swain MG, MacArthur L, Vergalla J, Jones EA. Adrenal secretion of BAM-22P, a potent opioid peptide, is enhanced in rats with acute cholestasis. Am J Physiol 1994; 266: G201-5.
    • (1994) Am J Physiol , vol.266
    • Swain, M.G.1    MacArthur, L.2    Vergalla, J.3    Jones, E.A.4
  • 17
    • 0036679047 scopus 로고    scopus 로고
    • Opiate antagonist therapy for the pruritus of cholestasis: The avoidance of opioid withdrawal-like reactions
    • Jones EA, Neuberger J, Bergasa NV. Opiate antagonist therapy for the pruritus of cholestasis: The avoidance of opioid withdrawal-like reactions. QJM 2002; 95: 547-52.
    • (2002) QJM , vol.95 , pp. 547-552
    • Jones, E.A.1    Neuberger, J.2    Bergasa, N.V.3
  • 18
    • 0036268170 scopus 로고    scopus 로고
    • Hepatic Met-enkephalin immunoreactivity is enhanced in primary biliary cirrhosis
    • Bergasa NV, Liau S, Homel P, Ghali V. Hepatic Met-enkephalin immunoreactivity is enhanced in primary biliary cirrhosis. Liver 2002; 22: 107-13.
    • (2002) Liver , vol.22 , pp. 107-113
    • Bergasa, N.V.1    Liau, S.2    Homel, P.3    Ghali, V.4
  • 19
    • 0028051829 scopus 로고
    • Methionine-enkephalin concentrations correlate with stage of disease but not pruritus in patients with primary biliary cirrhosis
    • Spivey JR, Jorgensen RA, Gores GJ, Lindor KD. Methionine-enkephalin concentrations correlate with stage of disease but not pruritus in patients with primary biliary cirrhosis. Am J Gastroenterol 1994; 89: 2028-32.
    • (1994) Am J Gastroenterol , vol.89 , pp. 2028-2032
    • Spivey, J.R.1    Jorgensen, R.A.2    Gores, G.J.3    Lindor, K.D.4
  • 20
    • 14944372161 scopus 로고    scopus 로고
    • Met-enkephalin modulation of age-related changes in red cell antioxidant status
    • Sobocanec S, Balog T, Sverko V, Marotti T. Met-enkephalin modulation of age-related changes in red cell antioxidant status. Physiol Res 2005; 54: 97-104.
    • (2005) Physiol Res , vol.54 , pp. 97-104
    • Sobocanec, S.1    Balog, T.2    Sverko, V.3    Marotti, T.4
  • 21
    • 33745251653 scopus 로고    scopus 로고
    • Methionine-enkephalin modulated regulation of oxidant/antioxidant status in liver of CBA mice
    • Sobocanec S, Kusic B, Sverko V, Balog T, Marotti T. Methionine-enkephalin modulated regulation of oxidant/antioxidant status in liver of CBA mice. Biogerontology 2006; 7: 53-62.
    • (2006) Biogerontology , vol.7 , pp. 53-62
    • Sobocanec, S.1    Kusic, B.2    Sverko, V.3    Balog, T.4    Marotti, T.5
  • 22
    • 0028968118 scopus 로고
    • The roles of reactive oxygen species and endogenous opioid peptides in ischemia-induced arrhythmia of isolated rat hearts
    • Yang CS, Tsai PJ, Chou ST, Niu YL, Lai JS, Kuo JS. The roles of reactive oxygen species and endogenous opioid peptides in ischemia-induced arrhythmia of isolated rat hearts. Free Radic Biol Med 1995; 18: 593-8.
    • (1995) Free Radic Biol Med , vol.18 , pp. 593-598
    • Yang, C.S.1    Tsai, P.J.2    Chou, S.T.3    Niu, Y.L.4    Lai, J.S.5    Kuo, J.S.6
  • 23
    • 4143066901 scopus 로고    scopus 로고
    • Opioids as modulators of cell death and survival - Unraveling mechanisms and revealing new indications
    • Tegeder I, Geisslinger G. Opioids as modulators of cell death and survival - unraveling mechanisms and revealing new indications. Pharmacol Rev 2004; 56: 351-69.
    • (2004) Pharmacol Rev , vol.56 , pp. 351-369
    • Tegeder, I.1    Geisslinger, G.2
  • 24
    • 2642546664 scopus 로고    scopus 로고
    • Morphine-induced macrophage apoptosis: Oxidative stress and strategies for modulation
    • Bhat RS, Bhaskaran M, Mongia A, Hitosugi N, Singhal PC. Morphine-induced macrophage apoptosis: Oxidative stress and strategies for modulation. J Leukoc Biol 2004; 75: 1131-8.
    • (2004) J Leukoc Biol , vol.75 , pp. 1131-1138
    • Bhat, R.S.1    Bhaskaran, M.2    Mongia, A.3    Hitosugi, N.4    Singhal, P.C.5
  • 25
    • 0025352380 scopus 로고
    • Modulation of superoxide anion release from human polymorphonuclear cells by Met-and Leu-enkephalin
    • Marotti T, Sverko V, Hrsak I. Modulation of superoxide anion release from human polymorphonuclear cells by Met-and Leu-enkephalin. Brain Behav Immun 1990; 4: 13-22.
    • (1990) Brain Behav Immun , vol.4 , pp. 13-22
    • Marotti, T.1    Sverko, V.2    Hrsak, I.3
  • 26
    • 4744370529 scopus 로고    scopus 로고
    • Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants
    • Zhang YT, Zheng QS, Pan J, Zheng RL. Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants. Basic Clin Pharmacol Toxicol 2004; 95: 53-58.
    • (2004) Basic Clin Pharmacol Toxicol , vol.95 , pp. 53-58
    • Zhang, Y.T.1    Zheng, Q.S.2    Pan, J.3    Zheng, R.L.4
  • 28
    • 7044253647 scopus 로고    scopus 로고
    • Opioid receptor blockade reduces Fas-induced hepatitis in mice
    • Jaume M, Jacquet S, Cavailles P, et al. Opioid receptor blockade reduces Fas-induced hepatitis in mice. Hepatology 2004; 40: 1136-43.
    • (2004) Hepatology , vol.40 , pp. 1136-1143
    • Jaume, M.1    Jacquet, S.2    Cavailles, P.3
  • 29
    • 33745964129 scopus 로고    scopus 로고
    • Chronic morphine treatment induces oxidant and apoptotic damage in the mice liver
    • Payabvash S, Beheshtian A, Salmasi AH, et al. Chronic morphine treatment induces oxidant and apoptotic damage in the mice liver. Life Sci 2006; 79: 972-80.
    • (2006) Life Sci , vol.79 , pp. 972-980
    • Payabvash, S.1    Beheshtian, A.2    Salmasi, A.H.3
  • 30
    • 0036399276 scopus 로고    scopus 로고
    • Do endogenous opioids contribute to the bradycardia of rats with obstructive cholestasis?
    • Gaskari SA, Mani AR, Ejtemaei-Mehr S, et al. Do endogenous opioids contribute to the bradycardia of rats with obstructive cholestasis? Fundam Clin Pharmacol 2002; 16: 273-9.
    • (2002) Fundam Clin Pharmacol , vol.16 , pp. 273-279
    • Gaskari, S.A.1    Mani, A.R.2    Ejtemaei-Mehr, S.3
  • 31
    • 33750377555 scopus 로고    scopus 로고
    • Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats
    • Ebrahimkhani MR, Kiani S, Oakley F, et al. Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats. Gut 2006; 55: 1606-16.
    • (2006) Gut , vol.55 , pp. 1606-1616
    • Ebrahimkhani, M.R.1    Kiani, S.2    Oakley, F.3
  • 32
    • 0028930691 scopus 로고
    • HPLC with o-phthalaldehyde precolumn derivatization to measure total, oxidized, and protein-bound glutathione in blood, plasma, and tissue
    • Paroni R, De Vecchi E, Cighetti G, et al. HPLC with o-phthalaldehyde precolumn derivatization to measure total, oxidized, and protein-bound glutathione in blood, plasma, and tissue. Clin Chem 1995; 41: 448-54.
    • (1995) Clin Chem , vol.41 , pp. 448-454
    • Paroni, R.1    De Vecchi, E.2    Cighetti, G.3
  • 33
    • 33751545345 scopus 로고    scopus 로고
    • Nitric oxide modulates glutathione synthesis during endotoxemia
    • Payabvash S, Ghahremani MH, Goliaei A, et al. Nitric oxide modulates glutathione synthesis during endotoxemia. Free Radic Biol Med 2006; 41: 1817-28.
    • (2006) Free Radic Biol Med , vol.41 , pp. 1817-1828
    • Payabvash, S.1    Ghahremani, M.H.2    Goliaei, A.3
  • 34
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 35
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med 1967; 70: 158-69.
    • (1967) J. Lab. Clin. Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 36
    • 0024991845 scopus 로고
    • Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation
    • Paoletti F, Mocali A. Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation. Methods Enzymol 1990; 186: 209-20.
    • (1990) Methods Enzymol , vol.186 , pp. 209-220
    • Paoletti, F.1    Mocali, A.2
  • 37
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-6.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 39
    • 0141892617 scopus 로고    scopus 로고
    • NFkappaB inhibition decreases hepatocyte proliferation but does not alter apoptosis in obstructive jaundice
    • Bird MA, Black D, Lange PA, Samson CM, Hayden M, Behrns KE. NFkappaB inhibition decreases hepatocyte proliferation but does not alter apoptosis in obstructive jaundice. J Surg Res 2003; 114: 110-7.
    • (2003) J Surg Res , vol.114 , pp. 110-117
    • Bird, M.A.1    Black, D.2    Lange, P.A.3    Samson, C.M.4    Hayden, M.5    Behrns, K.E.6
  • 40
    • 0034745492 scopus 로고    scopus 로고
    • NF-kB is activated in cholestasis and functions to reduce liver injury
    • Miyoshi H, Rust C, Guicciardi ME, Gores GJ. NF-kB is activated in cholestasis and functions to reduce liver injury. Am J Pathol 2001; 158: 967-75.
    • (2001) Am J Pathol , vol.158 , pp. 967-975
    • Miyoshi, H.1    Rust, C.2    Guicciardi, M.E.3    Gores, G.J.4
  • 41
    • 1242336980 scopus 로고    scopus 로고
    • Apoptosis: The nexus of liver injury and fibrosis
    • Canbay A, Friedman S, Gores GJ. Apoptosis: The nexus of liver injury and fibrosis. Hepatology 2004; 39: 273-8.
    • (2004) Hepatology , vol.39 , pp. 273-278
    • Canbay, A.1    Friedman, S.2    Gores, G.J.3
  • 42
    • 0021238490 scopus 로고
    • Prolonged bile duct obstruction: A new experimental model for cirrhosis in the rat
    • Kountouras J, Billing BH, Scheuer PJ. Prolonged bile duct obstruction: A new experimental model for cirrhosis in the rat. Br J Exp Pathol 1984; 65: 305-11.
    • (1984) Br J Exp Pathol , vol.65 , pp. 305-311
    • Kountouras, J.1    Billing, B.H.2    Scheuer, P.J.3
  • 43
    • 0031408388 scopus 로고    scopus 로고
    • Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine
    • Jones BA, Gores GJ. Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine. Am J Physiol 1997; 273: G1174-88.
    • (1997) Am J Physiol , vol.273
    • Jones, B.A.1    Gores, G.J.2
  • 44
    • 0035069055 scopus 로고    scopus 로고
    • Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
    • Sokol RJ, Straka MS, Dahl R, et al. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr Res 2001; 49: 519-31.
    • (2001) Pediatr Res , vol.49 , pp. 519-531
    • Sokol, R.J.1    Straka, M.S.2    Dahl, R.3
  • 45
    • 0035129976 scopus 로고    scopus 로고
    • Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
    • Yerushalmi B, Dahl R, Devereaux MW, Gumpricht E, Sokol RJ. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology 2001; 33: 616-26.
    • (2001) Hepatology , vol.33 , pp. 616-626
    • Yerushalmi, B.1    Dahl, R.2    Devereaux, M.W.3    Gumpricht, E.4    Sokol, R.J.5
  • 46
    • 0028910476 scopus 로고
    • Cholestasis is associated with preproenkephalin mRNA expression in the adult rat liver
    • Bergasa NV, Sabol SL, Young WS, Kleiner DE, Jones EA. Cholestasis is associated with preproenkephalin mRNA expression in the adult rat liver. Am J Physiol 1995; 268: G346-54.
    • (1995) Am J Physiol , vol.268
    • Bergasa, N.V.1    Sabol, S.L.2    Young, W.S.3    Kleiner, D.E.4    Jones, E.A.5
  • 47
    • 0025349994 scopus 로고
    • Drugs of abuse - Opiates
    • Ling W, Wesson DR. Drugs of abuse - opiates. West J Med 1990; 152: 565-72.
    • (1990) West J Med , vol.152 , pp. 565-572
    • Ling, W.1    Wesson, D.R.2
  • 48
    • 0033805442 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis
    • Kannan K, Jain SK. Oxidative stress and apoptosis. Pathophysiology 2000; 7: 153-63.
    • (2000) Pathophysiology , vol.7 , pp. 153-163
    • Kannan, K.1    Jain, S.K.2
  • 50
    • 0023239738 scopus 로고
    • A centrally-mediated effect of morphine to diminish hepatocellular glutathione
    • Roberts SM, Skoulis NP, James RC. A centrally-mediated effect of morphine to diminish hepatocellular glutathione. Biochem Pharmacol 1987; 36:3001-5.
    • (1987) Biochem Pharmacol , vol.36 , pp. 3001-3005
    • Roberts, S.M.1    Skoulis, N.P.2    James, R.C.3
  • 52
    • 0042766884 scopus 로고    scopus 로고
    • Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice
    • Gujral JS, Farhood A, Bajt ML, Jaeschke H. Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology 2003; 38: 355-63.
    • (2003) Hepatology , vol.38 , pp. 355-363
    • Gujral, J.S.1    Farhood, A.2    Bajt, M.L.3    Jaeschke, H.4
  • 53
    • 0021849844 scopus 로고
    • Naloxone inhibits superoxide release from human neutrophils
    • Simpkins CO, Ives N, Tate E, Johnson M. Naloxone inhibits superoxide release from human neutrophils. Life Sci 1985; 37: 1381-6.
    • (1985) Life Sci , vol.37 , pp. 1381-1386
    • Simpkins, C.O.1    Ives, N.2    Tate, E.3    Johnson, M.4
  • 54
    • 21244506076 scopus 로고    scopus 로고
    • Effects of naltrexone on lipopolysaccharide-induced sepsis in rats
    • Lin SL, Lee YM, Chang HY, Cheng YW, Yen MH. Effects of naltrexone on lipopolysaccharide-induced sepsis in rats. J Biomed Sci 2005; 12: 431-40.
    • (2005) J Biomed Sci , vol.12 , pp. 431-440
    • Lin, S.L.1    Lee, Y.M.2    Chang, H.Y.3    Cheng, Y.W.4    Yen, M.H.5
  • 57
    • 0032437544 scopus 로고    scopus 로고
    • Glutathione status in liver and plasma during development of biliary cirrhosis after bile duct ligation
    • Purucker E, Winograd R, Roeb E, Matern S. Glutathione status in liver and plasma during development of biliary cirrhosis after bile duct ligation. Res Exp Med 1998; 198: 167-74.
    • (1998) Res Exp Med , vol.198 , pp. 167-174
    • Purucker, E.1    Winograd, R.2    Roeb, E.3    Matern, S.4


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