Toxicological aspects and applications of nanoparticles in paediatric respiratory disease

Paediatric Respiratory Reviews

Volumn 8, Issue 1, 2007, Pages 62-66

  Dobson, Jon ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

gene therapy; imaging; nanoparticles; respiratory diseases; targeting; toxicology

Indexed keywords

ANTIBIOTIC AGENT; COAL; DEOXYRIBONUCLEASE; ENZYME; NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TUBERCULOSTATIC AGENT;

AIR POLLUTION; CHILD; CYSTIC FIBROSIS; DIAGNOSTIC IMAGING; EXHAUST GAS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INDUSTRY; LUNG TUBERCULOSIS; NANOTECHNOLOGY; NONHUMAN; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; REVIEW;

AIR POLLUTANTS; CHILD; DRUG DELIVERY SYSTEMS; HUMANS; LUNG DISEASES; NANOPARTICLES;

EID: 34047112207     PISSN: 15260542     EISSN: 15260550     Source Type: Journal    
DOI: 10.1016/j.prrv.2007.02.005     Document Type: Review

References (42)

1. Chang C.Y. The highlights in the nano world. Proc IEEE 91 (2003) 1756-1764
2. Dobson J. Magnetic nanoparticle-based targeting for drug and gene delivery. NanoMedicine 1 (2006) 31-37
3. Dobson J. Magnetic nanoparticles for drug delivery. Drug Devel Res 67 (2006) 55-60
4. Medintz I.L., Uyeda H.T., Goldman E.R., and Mattoussi H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 4 (2005) 435-446
5. Smith A.M., Dave S., Nie S.M., True L., and Gao X.H. Multicolor quantum dots for molecular diagnostics of cancer. Expert Rev Mol Diagnostics 6 (2006) 231-244
6. Borm P.J. Particle toxicology: from coal mining to nanotechnology. Inhal Toxicol 14 (2002) 311-324
7. Murr L.E., Esquivel E.V., and Bang J.J. Characterization of nanostructure phenomena in airborne particulate aggregates and their potential for respiratory health effects. J Mater Sci Mater Med 15 (2004) 237-247
8. Xiong C., and Friedlander S.K. Morphological properties of atmospheric aerosol aggregates. Proc Natl Acad Sci USA 98 (2001) 11851-11856
9. Chen Y., Chen J., Dong J., and Jin Y. Comparing study of the effect of nanosized silicon dioxide and microsized silicon dioxide on fibrogenesis in rats. Toxicol Ind Health 20 (2004) 21-27
10. 2 rods and dots in rats: toxicity is not dependent on particle size and surface area. Toxicol Sci 91 (2006) 227-236
11. Muller J., Huaux F., Moreau N., Misson P., et al. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 15 (2005) 221-231
12. Shvedova A.A., Kisin E.R., Mercer R., et al. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol 289 (2005) L698-L708
13. Fiorito S., Serafino A., Andreola F., Togna A., and Togna G. Toxicity and biocompatibility of carbon nanoparticles. J Nanosci Nanotechnol 6 (2006) 591-599
14. Sjøgren C.E., Briley-Saebø K., Hanson M., and Johansson C. Magnetic characterization of iron oxides for magnetic resonance imaging. Magn Reson Med 31 (1994) 268-272
15. Pankhurst Q.A., Connoly J., Jones S.K., and Dobson J. Applications of magnetic nanoparticles in biomedicine. J Phys D 36 (2003) R167-R181
16. Muldoon L.L., Sandor M., Pinkston K.E., and Neuwelt E.A. Imaging, distribution, and toxicity of superparamagnetic iron oxide magnetic resonance nanoparticles in the rat brain and intracerebral tumor. Neurosurgery 57 (2005) 785-796
17. Haage P., Karaagac S., Spuntrup E., Truong H.T., Schmidt T., and Gunther R.W. Feasibility of pulmonary ventilation visualization with aerosolized magnetic resonance contrast media. Invest Radiol 40 (2005) 85-88
18. Voura E.B., Jaiswal J.K., Mattoussi H., and Simon S.M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat Med 10 (2004) 993-998
19. Agrawal A., Tripp R.A., Anderson L.J., and Nie S. Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes. J Virol 79 (2005) 8625-8628
20. Johnson C.M., Pandey R., Sharma S., et al. Oral therapy using nanoparticle-encapsulated antituberculosis drugs in guinea pigs infected with Mycobacterium tuberculosis. Antimicrob Agents Chemother 49 (2005) 4335-4338
21. Sharma A., Sharma S., and Khuller G.K. Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis. J Antimicrob Chemother 54 (2004) 761-766
22. Zahoor A., Sharma S., and Khuller G.K. Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis. Int J Antimicrob Agents 26 (2005) 298-303
23. John A.E., Lukacs N.W., Berlin A.A., et al. Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease. FASEB J 17 (2003) 2296-2298
24. In: Hodson M.E., and Geddes D.M. (Eds). Cystic fibrosis (1995), Chapman & Hall Medical, London
25. Schildow D.V., and Friel S.B. Cystic fibrosis. In: Albert R.K., Spiro S.G., and Jett J.R. (Eds). Clinical Respiratory Medicine (2004), Mosby, St. Louis 19-29
26. Fuchs H.J., Borowitz D.S., Christiansen D.H., et al. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group. N Engl J Med 331 (1994) 637-642
27. Wagener J.S., Rock M.J., McCubbin M.M., Hamilton S.D., Johnson C.A., and Ahrens R.C. Aerosol delivery and safety of recombinant human deoxyribonuclease in young children with cystic fibrosis: a bronchoscopic study. Pulmozyme Pediatric Broncoscopy Study Group. J Pediat 133 (1998) 486-491
28. Bueler H. Adeno associated viral vectors for gene transfer and gene therapy. Biol Chem 380 (1999) 613-622
29. Wickham T.J. Targeting adenovirus. Gene Ther 7 (2000) 110-114
30. Zaiss A.K., and Muruve D.A. Immune responses to adeno-associated virus vectors. Curr Gene Ther 5 (2005) 323-331
31. Zhou H.S., Liu D.P., and Liang C.C. Challenges and strategies: The immune responses in gene therapy. Med Res Rev 24 (2004) 748-761
32. Riordan J.R., Rommens J.M., Kerem B., et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245 (1989) 1066-1072
33. Rommens J.M., Iannuzzi M.C., and Kerem B.S. Identification of the cystic fibrosis gene: Chromosome walking and jumping. Science 245 (1989) 1059-1065
34. Hyde S.C., Gill D.R., Higgins C.F., Trezise A.E., MacVinish L.J., Cuthbert A.W., Ratcliff R., Evans M.J., and Colledge W.H. Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature 362 (1993) 250-255
35. Gray M.A., Winpenny J.P., Porteous D.J., Dorin J.R., and Argent B.E. CFTR & calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Am J Physiol 266 (1994) 213-221
36. Alton E.W., Stern M., Farley R., et al. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial. Lancet 353 (1999) 947-954
37. Kitson C., Angel B., Judd D., et al. The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium. Gene Ther 6 (1999) 534-546
38. Ferrari S., Geddes D.M., and Alton E.W. Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis. Adv Drug Deliv Rev 54 (2002) 1373-1393
39. Halbert C.L., Stanaert T.A., Wilson C.B., and Miller A.B. Successful re-administration of adeno-associated virus vectors to mouse lung requires transient immunosuppression during the initial exposure. J Virol 72 (1998) 9795-9805
40. Zabner J., Ramsey B.W., Meeker D.P., et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. J Clin Invest 97 (1996) 1504-1511
41. Dobson J. Magnetic nanoparticle-based gene delivery. Gene Ther 13 (2006) 283-287
42. Xenariou S., Griesenbach U., Ferrari S., et al. Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo. Gene Ther 13 (2006) 1445-1452