Combinatorial search methods for multi-SNP disease association

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn , Issue , 2006, Pages 5802-5805

  Brinza, Dumitru ^a   He, Jingwu ^a   Zelikovsky, Alexander ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATIC INDEXING; BIOMARKERS; GENETIC ENGINEERING; NUCLEOTIDES; POLYMORPHISM;

COMBINATORIAL SEARCH METHODS; DISEASE ASSOCIATION; MULTILOCI ANALYSIS; MULTIMARKERS;

DISEASES;

ALLELE; ARTICLE; BIOLOGY; CHROMOSOME; COMPUTER PROGRAM; GENETIC DISORDER; GENETICS; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN GENOME; METHODOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

ALLELES; CHROMOSOMES; COMPUTATIONAL BIOLOGY; GENETIC DISEASES, INBORN; GENOME, HUMAN; GENOTYPE; HAPLOTYPES; HUMANS; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; SOFTWARE;

EID: 34047105143     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2006.260510     Document Type: Conference Paper

References (11)

1. Affymetrix (2005) http://www.affymetrix.com/proaucts/arrays/.
2. International HapMap Consortium. (2003) The International HapMap Project. Nature, 426, 789-796, http://www.hapmap.org.
3. Daly, M., Rioux, J., Schaffner, S., Hudson, T. and Lander, E. (2001) High resolution haplotype structure in the human genome. Nature Genetics, 29, 229-232.
4. Brinza, D. and Zelikovsky, A. (2006) 2SNP: Scalable Phasing Based on 2-SNP Haplotypes, Bioinformatics, 22(3), 371-373.
5. Clark AG. (2003) Finding Genes Underlying Risk of Complex Disease by Linkage Disequilibrium Mapping, Curr Opin Genet Dev., 13(3), 296-302.
6. Stephens, M., Smith, N.J., and Donnelly, P. (2001) A New Statistical Method for Haplotype Reconstruction from Population Data, The American Journal of Human Genetics, 68, 978-998.
7. Ueda, H., Howson, J.M.M., Esposito, L. et al. (2003) Association of the T Cell Regulatory Gene CTLA4 with Susceptibility to Autoimmune Disease, Nature, 423, 506-511.
8. He, J. and Zelikovsky, A. (2006) Tag SNP Selection Based on Multivariate Linear Regression, Proc. of Intl Conf on Computational Science (ICCS 2006), to appear.
9. Marchini, J., Donnelley, P. and Cardon, L.R, (2005) Genome-wide strategies for detecting multiple loci that influence complex diseases, Nature. Genetics, 37, 413-417.
10. Herbert, A., Gerry, N.P., McQueen, M.B. (2006) A Common Genetic Variant Is Associated with Adult and Childhood Obesity, SCIENCE, 312, 279-284.
11. Spinola, M., Meyer, P., Kammerer, S. et al. (2006) Association of the PDCD5 Locus With Lung Cancer Risk and Prognosis in Smokers, American Journal of Clinical Oncology, 24:11.