메뉴 건너뛰기




Volumn 30, Issue 3, 2007, Pages 709-715

Diverse activation states of RhoA in human lung cancer cells: Contribution of G protein coupled receptors

Author keywords

G protein coupled receptors; In vivo Rho guanine nucleotide exchange assay; Lung cancer; RhoA; YM 254890

Indexed keywords

CASPASE; G PROTEIN COUPLED RECEPTOR; GELATINASE A; GELATINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 33947718172     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.30.3.709     Document Type: Article
Times cited : (17)

References (36)
  • 1
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S and Hall A: Rho GTPases in cell biology. Nature 420: 629-635, 2002.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 2
    • 0032939619 scopus 로고    scopus 로고
    • Rho GTPases are over-expressed in human tumors
    • DOI 10.1002/(SICI)1097-0215(19990531)81:5<682::AID-IJC2>3.0.CO;2-B
    • Fritz G, Just I and Kaina B: Rho GTPases are over-expressed in human tumors. Int J Cancer 81: 682-687, 1999. (Pubitemid 29214373)
    • (1999) International Journal of Cancer , vol.81 , Issue.5 , pp. 682-687
    • Fritz, G.1    Just, I.2    Kaina, B.3
  • 3
    • 0033561508 scopus 로고    scopus 로고
    • Overexpression of small GTP-binding protein RhoA promotes invasion of tumor cells
    • Yoshioka K, Nakamori S and Itoh K: Overexpression of small GTP-binding protein RhoA promotes invasion of tumor cells. Cancer Res 59: 2004-2010, 1999.
    • (1999) Cancer Res , vol.59 , pp. 2004-2010
    • Yoshioka, K.1    Nakamori, S.2    Itoh, K.3
  • 4
    • 0035129473 scopus 로고    scopus 로고
    • Overexpression of RhoA mRNA is associated with advanced stage in testicular germ cell tumour
    • Kamai T, Arai K, Tsujii T, Honda M and Yoshida K: Overexpression of RhoA mRNA is associated with advanced stage in testicular germ cell tumour. BJU Int 87: 227-231, 2001.
    • (2001) BJU Int , vol.87 , pp. 227-231
    • Kamai, T.1    Arai, K.2    Tsujii, T.3    Honda, M.4    Yoshida, K.5
  • 6
    • 0031239882 scopus 로고    scopus 로고
    • The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells
    • Roux P, Gauthier-Rouviere C, Doucet-Brutin S and Fort P: The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells. Curr Biol 7: 629-637, 1997.
    • (1997) Curr Biol , vol.7 , pp. 629-637
    • Roux, P.1    Gauthier-Rouviere, C.2    Doucet-Brutin, S.3    Fort, P.4
  • 9
    • 0037048326 scopus 로고    scopus 로고
    • Rho GTPases in human breast tumours: Expression and mutation analyses and correlation with clinical parameters
    • Fritz G, Brachetti C, Bahlmann F, Schmidt M and Kaina B: Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters. Br J Cancer 87: 635-644, 2002.
    • (2002) Br J Cancer , vol.87 , pp. 635-644
    • Fritz, G.1    Brachetti, C.2    Bahlmann, F.3    Schmidt, M.4    Kaina, B.5
  • 10
    • 0035668525 scopus 로고    scopus 로고
    • Dbl family guanine nucleotide exchange factors
    • Zheng Y: Dbl family guanine nucleotide exchange factors. Trends Biochem Sci 26: 724-732, 2001.
    • (2001) Trends Biochem Sci , vol.26 , pp. 724-732
    • Zheng, Y.1
  • 11
    • 0037138364 scopus 로고    scopus 로고
    • Signaling to the Rho GTPases: Networking with the DH domain
    • Hoffman GR and Cerione RA: Signaling to the Rho GTPases: networking with the DH domain. FEBS Lett 513: 85-91, 2002.
    • (2002) FEBS Lett , vol.513 , pp. 85-91
    • Hoffman, G.R.1    Cerione, R.A.2
  • 12
    • 0036644975 scopus 로고    scopus 로고
    • Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
    • DOI 10.1101/gad.1003302
    • Schmidt A and Hall A: Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 16: 1587-1609, 2002. (Pubitemid 34743321)
    • (2002) Genes and Development , vol.16 , Issue.13 , pp. 1587-1609
    • Schmidt, A.1    Hall, A.2
  • 13
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB and Schwartz MA: Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18: 578-585, 1999.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 14
    • 0029658810 scopus 로고    scopus 로고
    • [D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells
    • Seckl MJ, Higgins T and Rozengurt E: [D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells. J Biol Chem 271: 29453-29460, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 29453-29460
    • Seckl, M.J.1    Higgins, T.2    Rozengurt, E.3
  • 15
    • 0030614842 scopus 로고    scopus 로고
    • [D-Arg1,D-Trp5,7,9,Leu11]substance P: A novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells
    • Seckl MJ, Higgins T, Widmer F and Rozengurt E: [D-Arg1,D-Trp5,7,9,Leu11] substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells. Cancer Res 57: 51-54, 1997.
    • (1997) Cancer Res , vol.57 , pp. 51-54
    • Seckl, M.J.1    Higgins, T.2    Widmer, F.3    Rozengurt, E.4
  • 17
    • 0037023691 scopus 로고    scopus 로고
    • Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: Evidence of a role for focal adhesion kinase
    • DOI 10.1074/jbc.M108504200
    • Chikumi H, Fukuhara S and Gutkind JS: Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase. J Biol Chem 277: 12463-12473, 2002. (Pubitemid 34952821)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.14 , pp. 12463-12473
    • Chikumi, H.1    Fukuhara, S.2    Gutkind, J.S.3
  • 18
    • 0028973505 scopus 로고
    • G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
    • Buhl AM, Johnson NL, Dhanasekaran N and Johnson GL: G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly. J Biol Chem 270: 24631-24634, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 24631-24634
    • Buhl, A.M.1    Johnson, N.L.2    Dhanasekaran, N.3    Johnson, G.L.4
  • 19
    • 0031984517 scopus 로고    scopus 로고
    • The many faces of G protein signaling
    • Hamm HE: The many faces of G protein signaling. J Biol Chem 273: 669-672, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 669-672
    • Hamm, H.E.1
  • 21
    • 0000737071 scopus 로고
    • Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells
    • Rozengurt E and Sinnett-Smith J: Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells. Proc Natl Acad Sci USA 80: 2936-2940, 1983.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2936-2940
    • Rozengurt, E.1    Sinnett-Smith, J.2
  • 22
    • 0023664210 scopus 로고
    • Identification of a receptor for peptides of the bombesin family in Swiss 3T3 cells by affinity cross-linking
    • Zachary I and Rozengurt E: Identification of a receptor for peptides of the bombesin family in Swiss 3T3 cells by affinity cross-linking. J Biol Chem 262: 3947-3950, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 3947-3950
    • Zachary, I.1    Rozengurt, E.2
  • 24
    • 0642348940 scopus 로고    scopus 로고
    • The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies
    • Varker KA, Phelps SH, King MM and Williams CL: The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies. Int J Oncol 22: 671-681, 2003.
    • (2003) Int J Oncol , vol.22 , pp. 671-681
    • Varker, K.A.1    Phelps, S.H.2    King, M.M.3    Williams, C.L.4
  • 25
    • 0021807624 scopus 로고
    • Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
    • Cuttitta F, Carney DN, Mulshine J, Moody TW, Fedorko J, Fischler A and Minna JD: Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature 316: 823-826, 1985.
    • (1985) Nature , vol.316 , pp. 823-826
    • Cuttitta, F.1    Carney, D.N.2    Mulshine, J.3    Moody, T.W.4    Fedorko, J.5    Fischler, A.6    Minna, J.D.7
  • 27
    • 0035199383 scopus 로고    scopus 로고
    • G protein-coupled receptor signaling in human ductal pancreatic cancer cells: Neurotensin responsiveness and mitogenic stimulation
    • Ryder NM, Guha S, Hines OJ, Reber HA and Rozengurt E: G protein-coupled receptor signaling in human ductal pancreatic cancer cells: neurotensin responsiveness and mitogenic stimulation. J Cell Physiol 186: 53-64, 2001.
    • (2001) J Cell Physiol , vol.186 , pp. 53-64
    • Ryder, N.M.1    Guha, S.2    Hines, O.J.3    Reber, H.A.4    Rozengurt, E.5
  • 28
    • 0033664359 scopus 로고    scopus 로고
    • Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes
    • Benya RV, Kusui T, Katsuno T, Tsuda T, Mantey SA, Battey JF and Jensen RT: Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes. Mol Pharmacol 58: 1490-1501, 2000.
    • (2000) Mol Pharmacol , vol.58 , pp. 1490-1501
    • Benya, R.V.1    Kusui, T.2    Katsuno, T.3    Tsuda, T.4    Mantey, S.A.5    Battey, J.F.6    Jensen, R.T.7
  • 30
    • 0029994016 scopus 로고    scopus 로고
    • Neuropeptides stimulate tyrosine phosphorylation and tyrosine kinase activity in small cell lung cancer cell lines
    • Tallett A, Chilvers ER, MacKinnon AC, Haslett C and Sethi T: Neuropeptides stimulate tyrosine phosphorylation and tyrosine kinase activity in small cell lung cancer cell lines. Peptides 17: 665-673, 1996.
    • (1996) Peptides , vol.17 , pp. 665-673
    • Tallett, A.1    Chilvers, E.R.2    MacKinnon, A.C.3    Haslett, C.4    Sethi, T.5
  • 31
    • 0034730536 scopus 로고    scopus 로고
    • [D-Arg(1),D-Trp(5,7,9),Leu(11)]Substance P inhibits bombesin-induced mitogenic signal transduction mediated by both G(q) and G(12) in Swiss 3T3cells
    • Sinnett-Smith J, Santiskulvong C, Duque J and Rozengurt E: [D-Arg(1),D-Trp(5,7,9),Leu(11)]Substance P inhibits bombesin-induced mitogenic signal transduction mediated by both G(q) and G(12) in Swiss 3T3cells. J Biol Chem 275: 30644-30652, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 30644-30652
    • Sinnett-Smith, J.1    Santiskulvong, C.2    Duque, J.3    Rozengurt, E.4
  • 32
    • 27744535465 scopus 로고    scopus 로고
    • Pasteurella multocida toxin-induced activation of RhoA is mediated via two Galpha proteins Galpha q and Galpha 12/13
    • Orth JH, Lang S, Taniguchi M and Aktories K: Pasteurella multocida toxin-induced activation of RhoA is mediated via two Galpha proteins Galpha q and Galpha 12/13. J Biol Chem 280: 36701-36707, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 36701-36707
    • Orth, J.H.1    Lang, S.2    Taniguchi, M.3    Aktories, K.4
  • 33
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley AJ and Hall A: The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70: 389-399, 1992.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 34
    • 0027952703 scopus 로고
    • Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility
    • Takaishi K, Sasaki T, Kato M, Yamochi W, Kuroda S, Nakamura T, Takeichi M and Takai Y: Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene 9: 273-279, 1994. (Pubitemid 24020959)
    • (1994) Oncogene , vol.9 , Issue.1 , pp. 273-279
    • Takaishi, K.1    Sasaki, T.2    Kato, M.3    Yamochi, W.4    Kuroda, S.5    Nakamura, T.6    Takeichi, M.7    Takai, Y.8
  • 35
    • 0042203546 scopus 로고    scopus 로고
    • Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells
    • Maddala R, Reddy VN, Epstein DL and Rao V: Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells. Mol Vis 9: 329-336, 2003.
    • (2003) Mol Vis , vol.9 , pp. 329-336
    • Maddala, R.1    Reddy, V.N.2    Epstein, D.L.3    Rao, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.