[D-Arg1,D-Trp5,7,9,Leu11]substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells

Journal of Biological Chemistry

Volumn 271, Issue 46, 1996, Pages 29453-29460

  Seckl, Michael J ^a,b   Higgins, Theresa ^a   Rozengurt, Enrique ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BOMBESIN; MITOGEN ACTIVATED PROTEIN KINASE; SUBSTANCE P; VASOPRESSIN; CALCIUM; DRUG DERIVATIVE; MARCKS PROTEIN; MEMBRANE PROTEIN; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE; PROTEIN; PROTEIN KINASE; SIGNAL PEPTIDE; SUBSTANCE P, ARG(1) TRP(5,7,9) LEU(11); SUBSTANCE P, ARG(1)-TRP(5,7,9)-LEU(11)-; TYROSINE; VASOPRESSIN DERIVATIVE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; DOSE RESPONSE; ENZYME ACTIVATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL STRAIN 3T3; DNA REPLICATION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MOUSE; PHOSPHORYLATION;

3T3 CELLS; ANIMALS; BOMBESIN; CALCIUM; DNA REPLICATION; ENZYME ACTIVATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; PROTEIN KINASES; PROTEINS; SIGNAL TRANSDUCTION; SUBSTANCE P; TYROSINE; VASOPRESSINS;

EID: 0029658810     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.46.29453     Document Type: Article

References (61)

1. Zachary, I., Woll, P., and Rozengurt, E. (1987) Dev. Biol. 124, 295-308
2. Rozengurt, E. (1993) Trends Exp. Clin. Med. 3, 145-157
3. Zachary, I., Millar, J., Nanberg, E., Higgins, T., and Rozengurt, E. (1987) Biochem. Biophys. Res. Commun. 146, 456-460
4. Erusalimsky, J. D., Freidberg, I., and Razengurt, E. (1988) J. Biol. Chem. 263, 19188-19194
5. Erusalimsky, J., and Rozengurt, E. (1989) J. Cell Physiol. 141, 253-261
6. Coffer, A., Fabregat, I., Sinnett-Smith, J., and Rozengurt, E. (1990) FEBS Lett. 263, 80-84
7. Murphy, A. C., and Rozengurt, E. (1992) J. Biol. Chem. 267, 26296-25303
8. Strathmann, M., and Simon, M. I. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9113-9117
9. Wilkie, T. M., Scherte, P. A., Strathmann, M. P., and Slepak, V. Z. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10049-10053
10. Offermanns, S., Helier, E., Spicher, K., and Schultz, G. (1994) FEBS Lett. 349, 201-204
11. Shenker, A., Goldsmith, P., Unson, C. G., and Spiegel, A. M. (1991) Science 266, 9309-9313
12. Taylor, S. J., Chae, H. Z., Rhee, S. G., and Exton, J. H. (1991) Nature 350, 516-518
13. Blank, J. L., Ross, A. H., and Exton, J. H. (1991) J. Biol. Chem. 286, 18206-18216
14. Smrcka, A. V., Kepler, J. R., Brown, K. O., and Sternweis, P. C. (1991) Science 251, 804-807
15. Gutowski, S., Smrcka, A., Nowak, L., Wu, D., Simon, M., and Sternweis, P. C. (1991) J. Biol. Chem. 266, 20519-20524
16. Berstein, G., Blank, J. L., Smrcka, A. V., Higashijima, T., Sternweis, P. C., Exton, J. H., and Ross, E. M. (1992) J. Biol. Chem. 267, 8081-8088
17. Heslop, J. P., Blakeley, D. M., Brown, K. D., Irvine, R. F., and Berridge, M. J. (1986) Cell 47, 703-709
18. Issandou, M., and Rozengurt, E. (1990) J. Biol. Chem. 265, 11890-11896
19. Nanberg, E., and Rozengurt, E. (1988) EMBO J. 7, 2741-2747
20. Staddon, J. M., Barker, C. J., Murphy, A. C., Chanter, N., Lax, A. J., Michell, R. H., and Rozengurt, E. (1991) J. Biol. Chem. 266, 4840-4847
21. Zachary, I., Sinnett-Smith, J., and Rozengurt, E. (1986) J. Cell. Biol. 102, 2211-2222
22. Berridge, M. J. (1993) Nature 361, 315-325
23. Rozengurt, E. (1986) Science 234, 161-166
24. Brooks, S. F., Herget, T., Erusalimsky, J. D., and Rozengurt, E. (1991) EMBO J. 10, 2497-2505
25. Blackshear, P. J., Wen, L., Glynn, B. P., and Witters, L. A. (1986) J. Biol. Chem. 261, 1459-1469
26. Rodriguez, P. A., and Rozengurt, E. (1986) EMBO J. 5, 77-83
27. Pang, L., Decker, S. J., and Saltiel, A. R. (1993) Biochem. J. 289, 283-287
28. Withers, D. J., Bloom, S. R., and Rozengurt, E. (1995) J. Biol. Chem. 270, 21411-21419
29. Rozengurt, E. (1992) Curr. Opin. Cell. Biol. 4, 161-165
30. Zachary, I., Gil, J., Lehmann, W., Sinnett-Smith, J., and Rozengurt, E. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4577-4581
31. Leeb-Lundberg, L. M. F., and Song, X.-H. (1991) J. Biol. Chem 266, 7746-7749
32. Zachary, I., Sinnett-Smith, J., and Rozengurt, E. (1992) J. Biol. Chem. 287, 19031-19034
33. Zachary, I., and Rozengurt, E. (1992) Cell 71, 891-894
34. Sinnett-Smith, J., Zachary, I., Valverde, A. M., and Rozengurt, E. (1993) J. Biol. Chem. 268, 14261-14268
35. Seekl, M., and Rozengurt, E. (1993) J. Biol. Chem. 268, 9548-9554
36. Rozengurt, E. (1995) in Oxford Textbook of Oncology (Peckham M, Pinedo H, Veronesi U, eds) pp. 12-20, Oxford University Press, Oxford
37. Yano, T., Pinski, J., Groot, K., and Schally, A. V. (1992) Cancer Res. 52, 4545-4547
38. Pinski, J., Reile, H., Halmos, G., Groot, K., and Schally, A. V. (1994) Cancer Res. 54, 169-174
39. Woll, P. J., Sethi, T., and Rozengurt, E. (1993) Cancer Chemother. Chan 5, 128-145
40. Zachary, I., and Rozengurt, E. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 7616-7620
41. Sinnett-Smith, J., Lehmann, W., and Rozengurt, E. (1990) Biochem. J. 265, 80-84
42. Kiehne, K., and Rozengurt, E. (1994) J. Cell. Physiol. 160, 502-510
43. Rozengurt, E., and Sinnett-Smith, J. (1988) Prog. Nucleic Acid Res. Mol. Biol. 35, 261-295
44. Woll, P. J., and Rozengurt, E. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 1859-1863
45. Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R., and Soltoff, S. (1991) Cell 64, 281-302
46. Woll, P. J., and Rozengurt, E. (1990) Cancer Res. 50, 3968-3973
47. Sethi, T., Langdon, S. P., Smyth, J. F., and Rozengurt, E. (1992) Cancer Res. 52, (suppl.) 2737-2742
48. Langdon, S. P., Sethi, T., Ritchie, A., Muir, M., Smyth, J., and Rozengurt, E. (1992) Cancer Res. 52, 4554-4557
49. Mitchell, F. M., Heasley, L. E., Qian, N.-X., Zamarripa, J., and Johnson, G. L. (1995) J. Biol. Chem. 270, 8623-8628
50. Seckl, M. J., Newman, R. H., Freemont, P. S., and Rozengurt, E. (1995) J. Cell. Physiol. 163, 87-95
51. Dicker, P., and Rozengurt, E. (1980) Nature 287, 607-612
52. Tsien, R. Y., Pozzan, T., and Rink, T. J. (1982) Nature 295, 68-71
53. Erusalimsky, J. D., Brooks, S. F., Herget, T., Morris, C., and Rozengurt, E. (1991) J. Biol. Chem. 266, 7073-7080
54. Laemmli, U. K. (1970) Nature 227, 680-685
55. Davis, R. (1993) J. Biol. Chem. 268, 14553-14556
56. Jones, D. A., Cummings, J., Langdon, S. P., MacLellan, A. J., Higgins, T., Rozengurt, E., and Smyth, J. F. (1995) Peptides 16, 777-783
57. Seufferlein, T., Withers, D. J., and Rozengurt, E. (1996) J. Biol. Chem. 271, 21471-21477
58. Seckl, M. J., Morii, N., Narumiya, S., and Rozengurt, E. (1995) J. Biol. Chem. 270, 6984-6990
59. Rankin, S., Morii, N., Narumiya, S., and Rozengurt, E. (1994) FEBS Lett. 354, 315-319
60. Zachary, I., Sinnett-Smith, J., Turner, C. E., and Rozengurt, E. (1993) J. Biol. Chem 268, 22060-22065
61. Charlesworth, A., Broad, S., and Rozengurt, E. (1996) Oncogene 12, 1337-1345