Tyk2 signaling in host environment plays an important role in contraction of antigen-specific CD8+ T cells following a microbial infection

Journal of Immunology

Volumn 178, Issue 7, 2007, Pages 4482-4488

  Li, Wei ^a   Yamada, Hisakata ^a   Yajima, Toshiki ^a   Nakagawa, Ryusuke ^a   Shimoda, Kazuya ^c   Nakayama, Keiichi ^b   Yoshikai, Yasunobu ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FOCAL ADHESION KINASE 1; GAMMA INTERFERON; INTERLEUKIN 12; MONOCLONAL ANTIBODY; OVALBUMIN; RECOMBINANT GAMMA INTERFERON; RECOMBINANT PROTEIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL INFECTION; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; FLOW CYTOMETRY; IMMUNE RESPONSE; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 33947660137     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.7.4482     Document Type: Article

References (41)

1. Ihle, J. N. 1995. Cytokine receptor signalling. Nature 377: 591-594.
2. Shimoda, K., K. Kato, K. Aoki, T. Matsuda, A. Miyamoto, M. Shibamori, M. Yamashita, A. Numata, K. Takase, S. Kobayashi, et al. 2000. Tyk2 plays a restricted role in IFN α signaling, although it is required for IL-12-mediated T cell function. Immunity 13: 561-571.
3. Karaghiosoff, M., H. Neubauer, C. Lassnig, P. Kovarik, H. Schindler, H. Pircher, B. McCoy, C. Bogdan, T. Decker, G. Brem, et al. 2000. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 13: 549-560.
4. Shimoda, K., H. Tsutsui, K. Aoki, K. Kato, T. Matsuda, A. Numata, K. Takase, T. Yamamoto, H. Nukina, T. Hoshino, et al. 2002. Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice. Blood 99: 2094-2099.
5. Schleicher, U., J. Mattner, M. Bios, H. Schindler, M. Rollinghoff, M. Karaghiosoff, M. Muller, G. Werner-Felmayer, and C. Bogdan. 2004. Control of Leishmania major in the absence of Tyk2 kinase. Eur. J. Immunol. 34: 519-529.
6. Wong, P., and E. G. Pamer. 2003. CD8 T cell responses to infectious pathogens. Annu. Rev. Immunol. 21: 29-70.
7. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272: 54-60.
8. Schluns, K. S., and L. Lefrancois. 2003. Cytokine control of memory T-cell development and survival. Nat. Rev. Immunol. 3: 269-279.
9. Marrack, P., and J. Kappler. 2004. Control of T cell viability. Annu. Rev. Immunol. 22: 765-787.
10. Hildeman, D. A., Y. Zhu, T. C. Mitchell, P. Bouillet, A. Strasser, J. Kappler, and P. Marrack. 2002. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 16: 759-767.
11. Pellegrini, M., G. Belz, P. Bouillet, and A. Strasser. 2003. Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc. Natl. Acad. Sci. USA 100: 14175-14180.
12. Lohman, B. L., E. S. Razvi, and R. M. Welsh. 1996. T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions. J. Virol. 70: 8199-8203.
13. Nguyen, L. T., K. McKall-Faienza, A. Zakarian, D. E. Speiser, T. W. Mak, and P. S. Ohashi. 2000. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions. Eur. J. Immunol. 30: 683-688.
14. Van Parijs, L., D. A. Peterson, and A. K. Abbas. 1998. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 8: 265-274.
15. Strasser, A., and M. Pellegrini. 2004. T-lymphocyte death during shutdown of an immune response. Trends Immunol. 25: 610-615.
16. Yajima, T., K. Yoshihara, K. Nakazato, S. Kumabe, S. Koyasu, S. Sad, H. Shen, H. Kuwano, and Y. Yoshikai. 2006. IL-15 regulates CD8 T Cell contraction during primary infection 1. J. Immunol. 176: 507-515.
17. + T cell homeostasis by perform and interferon γ. Science 290: 1354-1358.
18. Badovinac, V. P., B. B. Porter, and J. T. Harty. 2004. CD8+ T cell contraction is controlled by early inflammation. Nat. Immunol. 5: 809-817.
19. + T cells responding to infection. J. Immunol. 174: 6791-6802.
20. Foulds, K. E., L. A. Zenewicz, D. J. Shedlock, J. Jiang, A. E. Troy, and H. Shen. 2002. CD4 and CD8 T cells are intrinsically different in their proliferative responses. J. Immunol. 168: 1528-1532.
21. Dunn, P. L., and R. J. North. 1991. Early γ interferon production by natural killer cells is important in defense against murine listeriosis. Infect. Immun. 59: 2892-2900.
22. Mercado, R., S. Vijh, S. E. Allen, K. Kerksiek, I. M. Pilip, and E. G. Pamer. 2000. Early programming of T cell populations responding to bacterial infection. J. Immunol. 165: 6833-6839.
23. Hiromatsu, K., Y. Yoshikai, G. Matsuzaki, S. Ohga, K. Muramori, K. Matsumoto, J. A. Bluestone, and K. Nomoto. 1992. A protective role of γ/δ T cells in primary infection with Listeria monocytogenes in mice. J. Exp. Med. 175: 49-56.
24. Andersson, A., W. J. Dai, J. P. Santo, and F. Brombacher. 1998. Early IFN-γ production and innate immunity during Listeria monocytogenes infection in the absence of NK cells. J. Immunol. 161: 5600-5606.
25. Suzue, K., T. Asai, T. Takeuchi, and S. Koyasu. 2003. In vivo role of IFN-γ produced by antigen-presenting cells in early host defense against intracellular pathogens. Eur. J. Immunol. 33: 2666-2675.
26. Way, S. S., and C. B. Wilson. 2004. Immunity and IFN-γ production during Listeria monocytogenes infection in the absence of T-bet. J. Immunol. 173: 5918-5922.
27. Nakajima, H., E. W. Shores, M. Noguchi, and W. J. Leonard. 1997. The common cytokine receptor γ chain plays an essential role in regulating lymphoid homeostasis. J. Exp. Med. 185: 189-195.
28. Vella, A. T., S. Dow, T. A. Potter, J. Kappler, and P. Marrack. 1998. Cytokine induced survival of activated T cells in vitro and in vivo. Proc. Natl. Acad. Sci. USA 95: 3810-3815.
29. Liu, Y., and C. A. Janeway, Jr. 1990. Interferon γ plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance. J. Exp. Med. 172: 1735-1739.
30. Chawla-Sarkar, M., D. J. Lindner, Y. F. Liu, B. R. Williams, G. C. Sen, R. H. Silverman, and E. C. Borden. 2003. Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 8: 237-249.
31. + T cell homeostasis. J. Immunol. 176: 735-739.
32. Valenzuela, J. O., C. D. Hammerbeck, and M. F. Mescher. 2005. Cutting edge: Bcl-3 up-regulation by signal 3 cytokine (IL-12) prolongs survival of antigen-activated CD8 T cells. J. Immunol. 174: 600-604.
33. Tough, D. F., P. Borrow, and J. Sprent. 1996. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 272: 1947-1950.
34. Marrack, P., J. Kappler, and T. Mitchell. 1999. Type I interferons keep activated T cells alive. J. Exp. Med. 189: 521-530.
35. Curtsinger, J. M., J. O. Valenzuela, P. Agarwal, D. Lins, and M. F. Mescher. 2005. Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J. Immunol. 174: 4465-4469.
36. Gett, A. V., F. Sallusto, A. Lanzavecchia, and J. Geginat. 2003. T cell fitness determined by signal strength. Nat. Immunol. 4: 355-360.
37. Becker, T. C., E. J. Wherry, D. Boone, K. Murali-Krishna, R. Antia, A. Ma, and R. Ahmed. 2002. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J. Exp. Med. 195: 1541-1548.
38. + T cells were indispensable for T cell memory. Proc. Natl. Acad. Sci. USA 100: 4724-4729.
39. + T cells following a microbe exposure. J. Immunol. 168: 1198-1203.
40. Zhang, X., S. Sun, I. Hwang, D. F. Tough, and J. Sprent. 1998. Potent and selective stimulation of memory-phenotype CD8 T cells in vivo by IL-15. Immunity 8: 591-599.
41. + cells. J. Exp. Med. 195: 283-293.