메뉴 건너뛰기




Volumn 72, Issue 4, 1998, Pages 237-243

Reactivating potency of obidoxime, pralidoxime, HI 6 and HLo 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds

Author keywords

Acetylcholinesterase; Organophosphates; Oxime; Reactivation

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; ACETYLCHOLINESTERASE; OBIDOXIME; ORGANOPHOSPHATE; ORGANOPHOSPHORUS COMPOUND; PRALIDOXIME; SARIN; SOMAN; TABUN;

EID: 0031978963     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050495     Document Type: Article
Times cited : (133)

References (45)
  • 1
    • 0028177946 scopus 로고
    • Contribution of direct actions of the oxime HI-6 in reversing soman-induced muscle weakness in the rat diaphragm
    • Adler M, Maxwell DM, Filbert MG, Deshpande SS (1994) Contribution of direct actions of the oxime HI-6 in reversing soman-induced muscle weakness in the rat diaphragm. Eur J Pharmacol 270: 9-16
    • (1994) Eur J Pharmacol , vol.270 , pp. 9-16
    • Adler, M.1    Maxwell, D.M.2    Filbert, M.G.3    Deshpande, S.S.4
  • 2
    • 0001861650 scopus 로고
    • Overview of the biological and clinical aspects of organophosphates and carbamates
    • Ballantyne B, Marrs TC (eds) Butterworth/Heinemann, Oxford
    • Ballantyne B, Marrs TC (1992) Overview of the biological and clinical aspects of organophosphates and carbamates. In: Ballantyne B, Marrs TC (eds) Clinical and experimental toxicology of organophosphates and carbamates. Butterworth/Heinemann, Oxford, pp 3-14
    • (1992) Clinical and Experimental Toxicology of Organophosphates and Carbamates , pp. 3-14
    • Ballantyne, B.1    Marrs, T.C.2
  • 3
    • 0013937113 scopus 로고
    • Factors influencing the rate of 'aging' in a series of alkyl methylphosphonyl-acetylcholinesterases
    • Berry WK, Davies DR (1966) Factors influencing the rate of 'aging' in a series of alkyl methylphosphonyl-acetylcholinesterases. Biochem J 100: 572-576
    • (1966) Biochem J , vol.100 , pp. 572-576
    • Berry, W.K.1    Davies, D.R.2
  • 4
    • 0003092357 scopus 로고
    • Efficacy, toxicity and clinical use of oximes in anticholinesterase poisoning
    • Ballantyne B, Marrs TC (eds) Butterworth/Heinemann, Oxford
    • Bismuth C, Inns RH, Marrs TC (1992) Efficacy, toxicity and clinical use of oximes in anticholinesterase poisoning. In: Ballantyne B, Marrs TC (eds) Clinical and experimental toxicology of organophosphates and carbamates. Butterworth/Heinemann, Oxford, pp 555-577
    • (1992) Clinical and Experimental Toxicology of Organophosphates and Carbamates , pp. 555-577
    • Bismuth, C.1    Inns, R.H.2    Marrs, T.C.3
  • 5
    • 0026575362 scopus 로고
    • Efficacy of various oximes against GF (cyclohexylmethylphosphonofluoridate) poisoning in mice
    • Clement JG (1992) Efficacy of various oximes against GF (cyclohexylmethylphosphonofluoridate) poisoning in mice. Arch Toxicol 66: 143-144
    • (1992) Arch Toxicol , vol.66 , pp. 143-144
    • Clement, J.G.1
  • 6
    • 0028134939 scopus 로고
    • In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human
    • Clement JG, Erhardt N (1994) In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human. Arch Toxicol 68: 648-655
    • (1994) Arch Toxicol , vol.68 , pp. 648-655
    • Clement, J.G.1    Erhardt, N.2
  • 7
    • 0026609482 scopus 로고
    • Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice
    • Clement JG, Hansen AS, Boulet CA (1992) Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice. Arch Toxicol 66: 216-219
    • (1992) Arch Toxicol , vol.66 , pp. 216-219
    • Clement, J.G.1    Hansen, A.S.2    Boulet, C.A.3
  • 8
    • 0029061042 scopus 로고
    • The acetylcholinesterase oxime reactivator HI-6 in man: Pharmacokinetics and tolerability in combination with atropine
    • Clement JG, Bailey DG, Madill HD, Tran LT, Spence JD (1995) The acetylcholinesterase oxime reactivator HI-6 in man: pharmacokinetics and tolerability in combination with atropine. Biopharm Drug Dispos 16: 415-425
    • (1995) Biopharm Drug Dispos , vol.16 , pp. 415-425
    • Clement, J.G.1    Bailey, D.G.2    Madill, H.D.3    Tran, L.T.4    Spence, J.D.5
  • 9
    • 0014244174 scopus 로고
    • Cholinolytics in the treatment of anticholinesterase poisoning. V. The effectiveness of Parpanit with oximes in the treatment of organophosphorus poisoning
    • Coleman IW (1968) Cholinolytics in the treatment of anticholinesterase poisoning. V. The effectiveness of Parpanit with oximes in the treatment of organophosphorus poisoning. Can J Physiol Pharmacol 46: 106-117
    • (1968) Can J Physiol Pharmacol , vol.46 , pp. 106-117
    • Coleman, I.W.1
  • 10
    • 0000259812 scopus 로고
    • Clinical management of acute organophosphate poisoning: An overview
    • Ballantyne B, Marrs TC (eds) Butterworth/Heinemann, Oxford
    • Johnson MK, Vale JA (1992) Clinical management of acute organophosphate poisoning: an overview. In: Ballantyne B, Marrs TC (eds) Clinical and experimental toxicology of organophosphates and carbamates. Butterworth/Heinemann, Oxford, pp 528-535
    • (1992) Clinical and Experimental Toxicology of Organophosphates and Carbamates , pp. 528-535
    • Johnson, M.K.1    Vale, J.A.2
  • 11
    • 0018159735 scopus 로고
    • Effect of 1-(ar)-alkyl-hydroxyiminomethyl-pyridinium salts on reactivation and aging of acetylcholinesterase inhibited by ethyldimethylphosphoramidocyanidate (tabun)
    • de Jong LPA, Wolring GZ (1978) Effect of 1-(ar)-alkyl-hydroxyiminomethyl-pyridinium salts on reactivation and aging of acetylcholinesterase inhibited by ethyldimethylphosphoramidocyanidate (tabun). Biochem Pharmacol 27: 2229-2235
    • (1978) Biochem Pharmacol , vol.27 , pp. 2229-2235
    • De Jong, L.P.A.1    Wolring, G.Z.2
  • 12
    • 0021140988 scopus 로고
    • Stereospecific reactivation by some Hagedorn-oximes of acetycholinesterases from various species including man inhibited by soman
    • de Jong LPA, Wolring GZ (1984) Stereospecific reactivation by some Hagedorn-oximes of acetycholinesterases from various species including man inhibited by soman. Biochem Pharmacol 33: 1119-1125
    • (1984) Biochem Pharmacol , vol.33 , pp. 1119-1125
    • De Jong, L.P.A.1    Wolring, G.Z.2
  • 13
    • 0020060692 scopus 로고
    • Reactivation of acetylcholinesterase inhibited by methamidophos and analogous (di)methylphosphoramidates
    • de Jong LPA, Wolring GZ, Benschop HP (1982) Reactivation of acetylcholinesterase inhibited by methamidophos and analogous (di)methylphosphoramidates. Arch Toxicol 49: 175-183
    • (1982) Arch Toxicol , vol.49 , pp. 175-183
    • De Jong, L.P.A.1    Wolring, G.Z.2    Benschop, H.P.3
  • 14
    • 0024599799 scopus 로고
    • The bispyridinium-dioxime HLö-7: A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman
    • de Jong LPA, Verhagen AAV, Langenberg JP, Hagedorn I, Löffler M (1989) The bispyridinium-dioxime HLö-7: a potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman. Biochem Pharmacol 38: 633-640
    • (1989) Biochem Pharmacol , vol.38 , pp. 633-640
    • De Jong, L.P.A.1    Verhagen, A.A.V.2    Langenberg, J.P.3    Hagedorn, I.4    Löffler, M.5
  • 16
    • 76549214184 scopus 로고
    • Zur Resorption und Ausscheidung von Toxogonin nach intramuskulärer Injektion am Menschen
    • Erdmann WD, Bosse I, Franke P (1965) Zur Resorption und Ausscheidung von Toxogonin nach intramuskulärer Injektion am Menschen. Dtsch Med Wochenschr 90: 1436-1438
    • (1965) Dtsch Med Wochenschr , vol.90 , pp. 1436-1438
    • Erdmann, W.D.1    Bosse, I.2    Franke, P.3
  • 18
    • 0014084603 scopus 로고
    • Reactivation by pyridinium aldoxime methochloride (PAM) of inhibited cholinesterase activity in dogs after poisoning with pinacolyl methylphosphonofluoridate (soman)
    • Fleisher JH, Harris LW, Murtha EF (1967) Reactivation by pyridinium aldoxime methochloride (PAM) of inhibited cholinesterase activity in dogs after poisoning with pinacolyl methylphosphonofluoridate (soman). J Pharmacol Exp Ther 156: 345-351
    • (1967) J Pharmacol Exp Ther , vol.156 , pp. 345-351
    • Fleisher, J.H.1    Harris, L.W.2    Murtha, E.F.3
  • 19
    • 0024545838 scopus 로고
    • Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2
    • Grubic Z, Tomazic A (1989) Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2. Arch Toxicol 63: 68-71
    • (1989) Arch Toxicol , vol.63 , pp. 68-71
    • Grubic, Z.1    Tomazic, A.2
  • 20
    • 0018183972 scopus 로고
    • Effects of 1,1′-oxydimethylene bis-(4-tert-butylpyridinium chloride) (SAD-128) and decamethonium on reactivation of soman- And sarin-inhibited cholinesterase by oximes
    • Harris LW, Heyl WC, Stitcher DL, Broomfield CA (1978) Effects of 1,1′-oxydimethylene bis-(4-tert-butylpyridinium chloride) (SAD-128) and decamethonium on reactivation of soman-and sarin-inhibited cholinesterase by oximes. Biochem Pharmacol 27: 757-761
    • (1978) Biochem Pharmacol , vol.27 , pp. 757-761
    • Harris, L.W.1    Heyl, W.C.2    Stitcher, D.L.3    Broomfield, C.A.4
  • 21
    • 0002073816 scopus 로고
    • In vitro reactivation and "ageing" of tabun-inhibited blood cholinesterase
    • Heilbronn E (1963) In vitro reactivation and "ageing" of tabun-inhibited blood cholinesterase. Biochem Pharmacol 12: 25-36
    • (1963) Biochem Pharmacol , vol.12 , pp. 25-36
    • Heilbronn, E.1
  • 22
    • 0029874674 scopus 로고    scopus 로고
    • Oxime-induced reactivation of acetylcholinesterase inhibited by phosphoramidates
    • Jokanovic M, Maksimovic M, Kilibarda V, Jovanovic D, Savic D (1996) Oxime-induced reactivation of acetylcholinesterase inhibited by phosphoramidates. Toxicol Lett 85: 35-39
    • (1996) Toxicol Lett , vol.85 , pp. 35-39
    • Jokanovic, M.1    Maksimovic, M.2    Kilibarda, V.3    Jovanovic, D.4    Savic, D.5
  • 23
    • 0028791449 scopus 로고
    • Comparison of the efficacy of HI-6 and obidoxime against cyclohexyl melhyl-phosphonofluoridate (GF) in rats
    • Kassa J, Bajgar J (1995) Comparison of the efficacy of HI-6 and obidoxime against cyclohexyl melhyl-phosphonofluoridate (GF) in rats. Hum Exp Toxicol 14: 923-928
    • (1995) Hum Exp Toxicol , vol.14 , pp. 923-928
    • Kassa, J.1    Bajgar, J.2
  • 24
    • 0026673319 scopus 로고
    • Evaluation of the toxicity, pathology and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys
    • Koplovitz I, Gresham VC, Dochterman LW, Kaminskis A, Stewart JR (1992) Evaluation of the toxicity, pathology and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys. Arch Toxicol 66: 622-628
    • (1992) Arch Toxicol , vol.66 , pp. 622-628
    • Koplovitz, I.1    Gresham, V.C.2    Dochterman, L.W.3    Kaminskis, A.4    Stewart, J.R.5
  • 25
    • 0022369037 scopus 로고
    • HI-6 in man: Blood levels, urinary excretion and tolerance after intramuscular administration of the oxime to healthy volunteers
    • Kusic R, Boskovic B, Vojvodic V, Jovanovic D (1985) HI-6 in man: blood levels, urinary excretion and tolerance after intramuscular administration of the oxime to healthy volunteers. Fundam Appl Toxicol 5: S89-S97
    • (1985) Fundam Appl Toxicol , vol.5
    • Kusic, R.1    Boskovic, B.2    Vojvodic, V.3    Jovanovic, D.4
  • 26
    • 0026568340 scopus 로고
    • Comparison of several oximes against poisoning by soman, tabun and GF
    • Lundy PM, Hansen AS, Hand BT, Boulet CA (1992) Comparison of several oximes against poisoning by soman, tabun and GF. Toxicology 72: 99-105
    • (1992) Toxicology , vol.72 , pp. 99-105
    • Lundy, P.M.1    Hansen, A.S.2    Hand, B.T.3    Boulet, C.A.4
  • 27
    • 0025739914 scopus 로고
    • On the mechanism whereby HI-6 improves neuromuscular function after oxime-resistant acetylcholinesterase inhibition and subsequent impairment of neuromuscular transmission
    • Melchers BPC, van der Laaken AL, Van Helden HPM (1991) On the mechanism whereby HI-6 improves neuromuscular function after oxime-resistant acetylcholinesterase inhibition and subsequent impairment of neuromuscular transmission. Eur J Pharmacol 200: 331-337
    • (1991) Eur J Pharmacol , vol.200 , pp. 331-337
    • Melchers, B.P.C.1    Van Der Laaken, A.L.2    Van Helden, H.P.M.3
  • 30
    • 0022553280 scopus 로고
    • Reactivation of nerve agent inhibited human acetylcholinesterases by HI-6 and obidoxime
    • Puu G, Artursson E, Bucht G (1986) Reactivation of nerve agent inhibited human acetylcholinesterases by HI-6 and obidoxime. Biochem Pharmacol 35: 1505-1510
    • (1986) Biochem Pharmacol , vol.35 , pp. 1505-1510
    • Puu, G.1    Artursson, E.2    Bucht, G.3
  • 31
  • 33
    • 0014799059 scopus 로고
    • Toxogonin: Blood levels and side effects after intramuscular administration in man
    • Sidell FR, Groff WA (1970) Toxogonin: blood levels and side effects after intramuscular administration in man. J Pharmacol Sci 59: 793-797
    • (1970) J Pharmacol Sci , vol.59 , pp. 793-797
    • Sidell, F.R.1    Groff, W.A.2
  • 34
    • 0015103113 scopus 로고
    • Intramuscular and intravenous administration of small doses of 2-pyridinium aldoxime methochloride to man
    • Sidell FR, Groff WA (1971) Intramuscular and intravenous administration of small doses of 2-pyridinium aldoxime methochloride to man. J Pharmacol Sci 60: 1224-1228
    • (1971) J Pharmacol Sci , vol.60 , pp. 1224-1228
    • Sidell, F.R.1    Groff, W.A.2
  • 35
    • 0015964160 scopus 로고
    • The reactivatibility of cholinesterase inhibited by VX and sarin in man
    • Sidell FR, Groff WA (1974) The reactivatibility of cholinesterase inhibited by VX and sarin in man. Toxicol Appl Pharmacol 27: 241-252
    • (1974) Toxicol Appl Pharmacol , vol.27 , pp. 241-252
    • Sidell, F.R.1    Groff, W.A.2
  • 36
    • 0018836315 scopus 로고
    • Reactivating and protective effects of pyridinium compounds in human erythrocyte acetylcholinesterase inhibition by organophosphates in vitro
    • Skrinjaric-Spoljar M, Kralj M (1980) Reactivating and protective effects of pyridinium compounds in human erythrocyte acetylcholinesterase inhibition by organophosphates in vitro. Arch Toxicol 45: 21-27
    • (1980) Arch Toxicol , vol.45 , pp. 21-27
    • Skrinjaric-Spoljar, M.1    Kralj, M.2
  • 37
    • 0019510791 scopus 로고
    • Analysis of oxime-induced neuromuscular recovery in guinea pig, rat and man following soman poisoning in vitro
    • Smith AP, Van Der Wiel HJ, Wolthuis OL (1981) Analysis of oxime-induced neuromuscular recovery in guinea pig, rat and man following soman poisoning in vitro. Eur J Pharmacol 70: 371-379
    • (1981) Eur J Pharmacol , vol.70 , pp. 371-379
    • Smith, A.P.1    Van Der Wiel, H.J.2    Wolthuis, O.L.3
  • 38
    • 0027963222 scopus 로고
    • Pharmacokinetics of the oximes HI 6 and HLö 7 in dogs after i.m. injection with newly developed dry/wet autoinjectors
    • Spöhrer U, Thiermann H, Klimmek R, Eyer P (1994) Pharmacokinetics of the oximes HI 6 and HLö 7 in dogs after i.m. injection with newly developed dry/wet autoinjectors. Arch Toxicol 68: 480-489
    • (1994) Arch Toxicol , vol.68 , pp. 480-489
    • Spöhrer, U.1    Thiermann, H.2    Klimmek, R.3    Eyer, P.4
  • 39
    • 0022517214 scopus 로고
    • Reactivation of sarin- Or somanphosphonylated human acetylcholinesterase by bis-pyridinium mono-oximes
    • Sun MC, Li FZ, Chou TC (1986) Reactivation of sarin-or somanphosphonylated human acetylcholinesterase by bis-pyridinium mono-oximes. Biochem Pharmacol 35: 347-349
    • (1986) Biochem Pharmacol , vol.35 , pp. 347-349
    • Sun, M.C.1    Li, F.Z.2    Chou, T.C.3
  • 41
    • 0023772927 scopus 로고
    • A comparison of in vivo and in vitro rates of aging of soman-inhibited erythrocyte acetylcholinesterase in different animal species
    • Talbot BG, Anderson DR, Harris LW, Yarbrough LW, Lennox WJ (1988) A comparison of in vivo and in vitro rates of aging of soman-inhibited erythrocyte acetylcholinesterase in different animal species. Drug Chem Toxicol 11: 289-305
    • (1988) Drug Chem Toxicol , vol.11 , pp. 289-305
    • Talbot, B.G.1    Anderson, D.R.2    Harris, L.W.3    Yarbrough, L.W.4    Lennox, W.J.5
  • 43
    • 0019421235 scopus 로고
    • The efficacy of some bis-pyridinium oximes as antidotes to soman in isolated muscles of several species including man
    • Wolthuis OL, Vanwersch RAP, Van Der Wiel HJ (1981) The efficacy of some bis-pyridinium oximes as antidotes to soman in isolated muscles of several species including man. Eur J Pharmacol 70: 355-369
    • (1981) Eur J Pharmacol , vol.70 , pp. 355-369
    • Wolthuis, O.L.1    Vanwersch, R.A.P.2    Van Der Wiel, H.J.3
  • 44
    • 0029930604 scopus 로고    scopus 로고
    • Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds
    • Worek F, Kirchner T, Bäcker M, Szinicz L (1996) Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds. Arch Toxicol 70: 497-503
    • (1996) Arch Toxicol , vol.70 , pp. 497-503
    • Worek, F.1    Kirchner, T.2    Bäcker, M.3    Szinicz, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.