Induction of RNase H activity by arabinose-peptide nucleic acid chimeras

Bioconjugate Chemistry

Volumn 18, Issue 2, 2007, Pages 421-430

  Pâtureau, Bénédicte M ^a   Hudson, Robert H E ^b   Damha, Masad J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGOMERS; OLIGONUCLEOTIDES; PEPTIDES;

2-DEOXY-2; ANTISENSE OLIGONUCLEOTIDES; BASE COMPOSITION; BUTANEDIOL; CHIMERIC OLIGOMERS; HYBRID DUPLEX; MIXED-BASE; PEPTIDE NUCLEIC ACID; RNASE H; STRUCTURAL IMPERFECTIONS;

RNA;

2' DEOXY 2' FLUOROARABINONUCLEIC ACID; ANTISENSE OLIGONUCLEOTIDE; ARABINOSE; BUTANEDIOL; COMPLEMENTARY RNA; DNA; HETERODUPLEX; OLIGOMER; PEPTIDE NUCLEIC ACID; RIBONUCLEASE H; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CHIMERA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; HUMAN; RNA DEGRADATION; RNA HYBRIDIZATION; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY;

EID: 33947625050     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc060300r     Document Type: Article

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