메뉴 건너뛰기




Volumn 41, Issue 12, 2006, Pages 1238-1239

Smoothened gene mutations found in digestive cancer have no aberrant Hedgehog signaling activity [2]

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; G PROTEIN COUPLED RECEPTOR; PATCHED RECEPTORS; SMO PROTEIN, HUMAN;

EID: 33947601657     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-006-1955-2     Document Type: Letter
Times cited : (9)

References (6)
  • 1
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • 14520411 10.1038/nature01972 1:CAS:528:DC%2BD3sXotlWqsLc%3D
    • DM Berman SS Karhadkar A Maitra R Montes De Oca MR Gerstenblith K Briggs 2003 Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours Nature 425 846-51 14520411 10.1038/nature01972 1:CAS:528:DC%2BD3sXotlWqsLc%3D
    • (2003) Nature , vol.425 , pp. 846-851
    • Berman, D.M.1    Karhadkar, S.S.2    Maitra, A.3    Montes De Oca, R.4    Gerstenblith, M.R.5    Briggs, K.6
  • 2
    • 28244447471 scopus 로고    scopus 로고
    • p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells
    • 16322228 10.1158/0008-5472.CAN-05-0777 1:CAS:528:DC%2BD2MXht1Kjsr7F
    • M Ohta K Tateishi F Kanai H Watabe S Kondo B Guleng 2005 p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells Cancer Res 65 10822-9 16322228 10.1158/ 0008-5472.CAN-05-0777 1:CAS:528:DC%2BD2MXht1Kjsr7F
    • (2005) Cancer Res , vol.65 , pp. 10822-10829
    • Ohta, M.1    Tateishi, K.2    Kanai, F.3    Watabe, H.4    Kondo, S.5    Guleng, B.6
  • 3
    • 0031913524 scopus 로고    scopus 로고
    • Activating Smoothened mutations in sporadic basal-cell carcinoma
    • 9422511 10.1038/34201 1:CAS:528:DyaK1cXktVSksA%3D%3D
    • J Xie M Murone SM Luoh A Ryan Q Gu C Zhang 1998 Activating Smoothened mutations in sporadic basal-cell carcinoma Nature 391 90-2 9422511 10.1038/34201 1:CAS:528:DyaK1cXktVSksA%3D%3D
    • (1998) Nature , vol.391 , pp. 90-92
    • Xie, J.1    Murone, M.2    Luoh, S.M.3    Ryan, A.4    Gu, Q.5    Zhang, C.6
  • 4
    • 1842557424 scopus 로고    scopus 로고
    • Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells
    • 15072830 10.1016/j.canlet.2003.10.025 1:CAS:528:DC%2BD2cXjtV2nsrk%3D
    • Y Zhu RM James A Peter C Lomas F Cheung DJ Harrison 2004 Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells Cancer Lett 207 205-14 15072830 10.1016/j.canlet.2003.10.025 1:CAS:528:DC%2BD2cXjtV2nsrk%3D
    • (2004) Cancer Lett , vol.207 , pp. 205-214
    • Zhu, Y.1    James, R.M.2    Peter, A.3    Lomas, C.4    Cheung, F.5    Harrison, D.J.6
  • 5
    • 0030891148 scopus 로고    scopus 로고
    • A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro
    • 9118802 1:CAS:528:DyaK2sXivFKhtrY%3D
    • H Sasaki C Hui M Nakafuku H Kondoh 1997 A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro Development 124 1313-22 9118802 1:CAS:528:DyaK2sXivFKhtrY%3D
    • (1997) Development , vol.124 , pp. 1313-1322
    • Sasaki, H.1    Hui, C.2    Nakafuku, M.3    Kondoh, H.4
  • 6
    • 0034738979 scopus 로고    scopus 로고
    • Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
    • 10984056 10.1038/35023008 1:CAS:528:DC%2BD3cXmtlOjtrs%3D
    • J Taipale JK Chen MK Cooper B Wang RK Mann L Milenkovic 2000 Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine Nature 406 1005-9 10984056 10.1038/35023008 1:CAS:528:DC%2BD3cXmtlOjtrs%3D
    • (2000) Nature , vol.406 , pp. 1005-1009
    • Taipale, J.1    Chen, J.K.2    Cooper, M.K.3    Wang, B.4    Mann, R.K.5    Milenkovic, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.