DNA-damaging ability of isoprene and isoprene mono-epoxide (EPOX I) in human cells evaluated with the comet assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 629, Issue 1, 2007, Pages 7-13

  Fabiani, Roberto ^a   Rosignoli, Patrizia ^a   De Bartolomeo, Angelo ^a   Fuccelli, Raffaela ^a   Morozzi, Guido ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Genotoxicity; Human cells; Isoprene; Isoprene monoepoxide; Metabolism; S9

Indexed keywords

3 METHYL 1 BUTENE 3,4 OXIDE; EPOXIDE; ISOPRENE; ISOPRENE MONOEPOXIDE; PHENOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL STRAIN HL 60; COMET ASSAY; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; MALE; METABOLIC ACTIVATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; BUTADIENES; CARCINOGENS; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; HEMITERPENES; HL-60 CELLS; HUMANS; KINETICS; LEUKOCYTES, MONONUCLEAR; MICROSOMES, LIVER; PENTANES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA; RATTUS;

EID: 33947600780     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.12.007     Document Type: Article

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