메뉴 건너뛰기




Volumn 10, Issue 2, 2007, Pages 97-111

Selective estrogen receptor modulators and risk for coronary heart disease

Author keywords

Atherosclerosis; Coronary heart disease; Estrogens; Serms; Thrombosis

Indexed keywords

1,1,2 TRIPHENYLETHYLENE DERIVATIVE; 4 [4 METHYL 2 [4 [2 (1 PIPERIDINYL)ETHOXY]PHENYL] 7 PIVALOYLOXY 2H 1 BENZOPYRAN 3 YLPHENYL] PIVALATE; ACOLBIFENE; ARZOXIFENE; BAZEDOXIFENE; BENZOPYRAN DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; CENTCHROMAN; CLOMIFENE; CONJUGATED ESTROGEN; DROLOXIFENE; ESTRADIOL; ESTROGEN; FULVESTRANT; IDOXIFENE; INDOLE DERIVATIVE; LASOFOXIFENE; MEDROXYPROGESTERONE ACETATE; MIPROXIFENE PHOSPHATE; NAPHTHALENE DERIVATIVE; OSPEMIFENE; PIPENDOXIFENE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TOREMIFENE; TRIOXIFENE;

EID: 33947593767     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.1080/13697130701258804     Document Type: Review
Times cited : (13)

References (121)
  • 1
    • 33947584623 scopus 로고    scopus 로고
    • American Heart Association (http://www.americanheart.org)
  • 3
    • 0031866317 scopus 로고    scopus 로고
    • Hormone replacement therapy, heart disease, and other considerations
    • Barrett-Connor E, Grady D. Hormone replacement therapy, heart disease, and other considerations. Annu Rev Public Health 1998;19:55-72
    • (1998) Annu Rev Public Health , vol.19 , pp. 55-72
    • Barrett-Connor, E.1    Grady, D.2
  • 4
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
    • Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998;280:605-13
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3
  • 5
    • 0037014584 scopus 로고    scopus 로고
    • Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II)
    • Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). JAMA 2002;288:49-57
    • (2002) JAMA , vol.288 , pp. 49-57
    • Grady, D.1    Herrington, D.2    Bittner, V.3
  • 6
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-33
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 7
    • 0034039060 scopus 로고    scopus 로고
    • Modulation of the oestrogen receptor: A process with distinct susceptible steps
    • Cano A, Hermenegildo C. Modulation of the oestrogen receptor: a process with distinct susceptible steps. Hum Reprod Update 2000;6:207-11
    • (2000) Hum Reprod Update , vol.6 , pp. 207-211
    • Cano, A.1    Hermenegildo, C.2
  • 9
    • 33646178259 scopus 로고    scopus 로고
    • Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions
    • Ouyang P, Michos ED, Karas RH. Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions. J Am Coll Cardiol 2006;47:1741-53
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1741-1753
    • Ouyang, P.1    Michos, E.D.2    Karas, R.H.3
  • 10
    • 33947574493 scopus 로고    scopus 로고
    • Estrogen receptor modulation
    • ed, Bologna, Italy: Medimond
    • Cano A. Estrogen receptor modulation. In Filicori M, ed. Updates in Infertility Treatment. Bologna, Italy: Medimond, 2004:265-80
    • (2004) Updates in Infertility Treatment , pp. 265-280
    • Cano, A.1
  • 11
    • 0030733906 scopus 로고    scopus 로고
    • Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern
    • Enmark E, Pelto-Huikko M, Grandien K, et al. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 1997;82:4258-65
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4258-4265
    • Enmark, E.1    Pelto-Huikko, M.2    Grandien, K.3
  • 12
    • 0037127027 scopus 로고    scopus 로고
    • Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta
    • Zhu Y, Bian Z, Lu P, et al. Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science 2002;295:505-8
    • (2002) Science , vol.295 , pp. 505-508
    • Zhu, Y.1    Bian, Z.2    Lu, P.3
  • 14
    • 0042934090 scopus 로고    scopus 로고
    • Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression
    • Harrington WR, Sheng S, Barnett DH, Petz LN, Katzenellenbogen JA, Katzenellenbogen BS. Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. Mol Cell Endocrinol 2003;206:13-22
    • (2003) Mol Cell Endocrinol , vol.206 , pp. 13-22
    • Harrington, W.R.1    Sheng, S.2    Barnett, D.H.3    Petz, L.N.4    Katzenellenbogen, J.A.5    Katzenellenbogen, B.S.6
  • 15
    • 0344670184 scopus 로고    scopus 로고
    • Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor
    • Muthyala RS, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor. J Med Chem 2003;46:1589-602
    • (2003) J Med Chem , vol.46 , pp. 1589-1602
    • Muthyala, R.S.1    Sheng, S.2    Carlson, K.E.3    Katzenellenbogen, B.S.4    Katzenellenbogen, J.A.5
  • 16
    • 0037245578 scopus 로고    scopus 로고
    • Estrogenic diazenes: Heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes
    • Ghosh U, Ganessunker D, Sattigeri VJ, et al. Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes. Bioorg Med Chem 2003;11:629-57
    • (2003) Bioorg Med Chem , vol.11 , pp. 629-657
    • Ghosh, U.1    Ganessunker, D.2    Sattigeri, V.J.3
  • 17
    • 0030633188 scopus 로고    scopus 로고
    • Role of co-activators and co-repressors in the mechanism of steroid-thyroid receptor action
    • Shibata H, Spencer TE, Onãte SA, et al. Role of co-activators and co-repressors in the mechanism of steroid-thyroid receptor action. Rec Prog Horm Res 1997;52:141-65
    • (1997) Rec Prog Horm Res , vol.52 , pp. 141-165
    • Shibata, H.1    Spencer, T.E.2    Onãte, S.A.3
  • 18
    • 0035813112 scopus 로고    scopus 로고
    • The multifaceted mechanisms of estradiol and estrogen receptor signaling
    • Hall JM, Couse JF, Korach KS. The multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem 2001;276:36869-72
    • (2001) J Biol Chem , vol.276 , pp. 36869-36872
    • Hall, J.M.1    Couse, J.F.2    Korach, K.S.3
  • 19
    • 0038819062 scopus 로고    scopus 로고
    • Kinasemediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
    • Kousteni S, Han L, Chen JR, et al. Kinasemediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest 2003;111:1651-64
    • (2003) J Clin Invest , vol.111 , pp. 1651-1664
    • Kousteni, S.1    Han, L.2    Chen, J.R.3
  • 20
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells
    • Li L, Haynes MP, Bender JR. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc Natl Acad Sci USA 2003;100:4807-12
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4807-4812
    • Li, L.1    Haynes, M.P.2    Bender, J.R.3
  • 21
    • 0034735852 scopus 로고    scopus 로고
    • Mechanisms of estrogen action in the cardiovascular system
    • Mendelsohn ME. Mechanisms of estrogen action in the cardiovascular system. J Steroid Biochem Mol Biol 2000;74:337-43
    • (2000) J Steroid Biochem Mol Biol , vol.74 , pp. 337-343
    • Mendelsohn, M.E.1
  • 22
    • 0037014416 scopus 로고    scopus 로고
    • Mendelsohn ME. Genomic and nongenomic effects of estrogen in the vasculature. Am J Cardiol 2002;90(1A):3-6F
    • Mendelsohn ME. Genomic and nongenomic effects of estrogen in the vasculature. Am J Cardiol 2002;90(1A):3-6F
  • 23
    • 33947591771 scopus 로고    scopus 로고
    • Clinical Pharmacology of selective estrogen receptor modulators (SERMs)
    • Cano A, Calaf i Alsina J, Duenas-Diez JL, eds, Berlin, Germany: Springer
    • Marin F, Barbancho MC. Clinical Pharmacology of selective estrogen receptor modulators (SERMs). In Cano A, Calaf i Alsina J, Duenas-Diez JL, eds. Selective Estrogen Receptor Modulators. New Brand of Multitarget Drugs. Berlin, Germany: Springer, 2006:49-69
    • (2006) Selective Estrogen Receptor Modulators. New Brand of Multitarget Drugs , pp. 49-69
    • Marin, F.1    Barbancho, M.C.2
  • 24
    • 33745249570 scopus 로고    scopus 로고
    • Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
    • Vogel VG, Costantino JP, Wickerham DL, et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA 2006;295:2727-41
    • (2006) JAMA , vol.295 , pp. 2727-2741
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3
  • 25
    • 33745876266 scopus 로고    scopus 로고
    • Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
    • Barrett-Connor E, Mosca L, Collins P, et al. Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N Engl J Med 2006;355:125-37
    • (2006) N Engl J Med , vol.355 , pp. 125-137
    • Barrett-Connor, E.1    Mosca, L.2    Collins, P.3
  • 26
    • 0037133569 scopus 로고    scopus 로고
    • Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene
    • Simoncini T, Genazzani AR, Liao JK. Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene. Circulation 2002;105:1368-73
    • (2002) Circulation , vol.105 , pp. 1368-1373
    • Simoncini, T.1    Genazzani, A.R.2    Liao, J.K.3
  • 27
    • 0036096224 scopus 로고    scopus 로고
    • Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator
    • Simoncini T, Varone G, Fornari L, et al. Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator. Endocrinology 2002;143:2052-61
    • (2002) Endocrinology , vol.143 , pp. 2052-2061
    • Simoncini, T.1    Varone, G.2    Fornari, L.3
  • 28
    • 4644342416 scopus 로고    scopus 로고
    • Raloxifene increases the capacity of serum to promote prostacyclin release in human endothelial cells: Implication of COX-1 and COX-2
    • Oviedo PJ, Hermenegildo C, Cano A. Raloxifene increases the capacity of serum to promote prostacyclin release in human endothelial cells: implication of COX-1 and COX-2. Menopause 2004;11:430-7
    • (2004) Menopause , vol.11 , pp. 430-437
    • Oviedo, P.J.1    Hermenegildo, C.2    Cano, A.3
  • 29
    • 20444496134 scopus 로고    scopus 로고
    • Raloxifene promotes prostacyclin release in human endothelial cells role of COX-1 and COX-2
    • Oviedo P, Hermenegildo C, Tarín JJ, Cano A. Raloxifene promotes prostacyclin release in human endothelial cells role of COX-1 and COX-2. Fertil Steril 2005;83:1822-9
    • (2005) Fertil Steril , vol.83 , pp. 1822-1829
    • Oviedo, P.1    Hermenegildo, C.2    Tarín, J.J.3    Cano, A.4
  • 30
    • 0036166858 scopus 로고    scopus 로고
    • Vasoregulation at the molecular level: A role for the beta1 subunit of the calcium-activated potassium (BK) channel
    • Patterson AJ, Henrie-Olson J, Brenner R. Vasoregulation at the molecular level: a role for the beta1 subunit of the calcium-activated potassium (BK) channel. Trends Cardiovasc Med 2002;12:78-82
    • (2002) Trends Cardiovasc Med , vol.12 , pp. 78-82
    • Patterson, A.J.1    Henrie-Olson, J.2    Brenner, R.3
  • 31
    • 0037066911 scopus 로고    scopus 로고
    • Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of calcium channels
    • Díaz M. Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of calcium channels. Eur J Pharmacol 2002;445:257-66
    • (2002) Eur J Pharmacol , vol.445 , pp. 257-266
    • Díaz, M.1
  • 33
    • 1642349571 scopus 로고    scopus 로고
    • Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism
    • Mercier I, Mader S, Calderone A. Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism. Cardiovasc Res 2003;59:883-92
    • (2003) Cardiovasc Res , vol.59 , pp. 883-892
    • Mercier, I.1    Mader, S.2    Calderone, A.3
  • 34
    • 0037192501 scopus 로고    scopus 로고
    • Molecular determinants for the tissue specificity of SERMs
    • Shang Y, Brown M. Molecular determinants for the tissue specificity of SERMs. Science 2002;295:2465-8
    • (2002) Science , vol.295 , pp. 2465-2468
    • Shang, Y.1    Brown, M.2
  • 35
    • 0036020055 scopus 로고    scopus 로고
    • Tamoxifen induces changes in the lipid composition of the retinal pigment epithelium cell line D407
    • Engelke M, Tykhonova S, Zorn-Kruppa M, Diehl H. Tamoxifen induces changes in the lipid composition of the retinal pigment epithelium cell line D407. Pharmacol Toxicol 2002;91:13-21
    • (2002) Pharmacol Toxicol , vol.91 , pp. 13-21
    • Engelke, M.1    Tykhonova, S.2    Zorn-Kruppa, M.3    Diehl, H.4
  • 36
    • 0027296162 scopus 로고
    • Tamoxifen and related compounds decrease membrane fluidity in liposomes. Mechanism for the antioxidant action of tamoxifen and relevance to its anticancer and cardioprotective actions?
    • Wiseman H, Quinn P, Halliwell B. Tamoxifen and related compounds decrease membrane fluidity in liposomes. Mechanism for the antioxidant action of tamoxifen and relevance to its anticancer and cardioprotective actions? FEBS Lett 1993;330:53-6
    • (1993) FEBS Lett , vol.330 , pp. 53-56
    • Wiseman, H.1    Quinn, P.2    Halliwell, B.3
  • 37
    • 3543101999 scopus 로고    scopus 로고
    • Inhibition of low-density lipoprotein and high-density lipoprotein oxidation by raloxifene
    • Resch U, Mellauner V, Budinsky A, Sinzinger H. Inhibition of low-density lipoprotein and high-density lipoprotein oxidation by raloxifene. J Womens Health (Larchmt) 2004;13:404-11
    • (2004) J Womens Health (Larchmt) , vol.13 , pp. 404-411
    • Resch, U.1    Mellauner, V.2    Budinsky, A.3    Sinzinger, H.4
  • 38
    • 0030604022 scopus 로고    scopus 로고
    • Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL)
    • Zuckerman SH, Bryan N. Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL). Atherosclerosis 1996;126:65-75
    • (1996) Atherosclerosis , vol.126 , pp. 65-75
    • Zuckerman, S.H.1    Bryan, N.2
  • 39
    • 0037709896 scopus 로고    scopus 로고
    • Raloxifene is a better antioxidant of low-density lipoprotein than estradiol or tamoxifen in postmenopausal women in vitro
    • Arteaga E, Villaseca P, Bianchi M, Rojas A, Marshall G. Raloxifene is a better antioxidant of low-density lipoprotein than estradiol or tamoxifen in postmenopausal women in vitro. Menopause 2003;10:142-6
    • (2003) Menopause , vol.10 , pp. 142-146
    • Arteaga, E.1    Villaseca, P.2    Bianchi, M.3    Rojas, A.4    Marshall, G.5
  • 40
    • 0036836119 scopus 로고    scopus 로고
    • Inhibition of low-density lipoprotein oxidation by the pure antiestrogens ICI 182780 and EM-652 (SCH 57068)
    • Hermenegildo C, Garcia-Martinez MC, Tarin JJ, Cano A. Inhibition of low-density lipoprotein oxidation by the pure antiestrogens ICI 182780 and EM-652 (SCH 57068). Menopause 2002;9:430-5
    • (2002) Menopause , vol.9 , pp. 430-435
    • Hermenegildo, C.1    Garcia-Martinez, M.C.2    Tarin, J.J.3    Cano, A.4
  • 41
    • 0034780364 scopus 로고    scopus 로고
    • Reduction of oxidative stress and AT1 receptor expression by the selective oestrogen receptor modulator idoxifene
    • Baumer AT, Wassmann S, Ahlbory K, et al. Reduction of oxidative stress and AT1 receptor expression by the selective oestrogen receptor modulator idoxifene. Br J Pharmacol 2001;134:579-84
    • (2001) Br J Pharmacol , vol.134 , pp. 579-584
    • Baumer, A.T.1    Wassmann, S.2    Ahlbory, K.3
  • 42
    • 0037059432 scopus 로고    scopus 로고
    • Raloxifene enhances nitric oxide release in rat aorta via increasing endothelial nitric oxide mRNA expression
    • Rahimian R, Dube GP, Toma W, Dos Santos N, McManus BM, van Breemen C. Raloxifene enhances nitric oxide release in rat aorta via increasing endothelial nitric oxide mRNA expression. Eur J Pharmacol 2002;434:141-9
    • (2002) Eur J Pharmacol , vol.434 , pp. 141-149
    • Rahimian, R.1    Dube, G.P.2    Toma, W.3    Dos Santos, N.4    McManus, B.M.5    van Breemen, C.6
  • 43
    • 0037141769 scopus 로고    scopus 로고
    • Idoxifene causes endothelium-dependent, nitric oxide-mediated vasorelaxation in male rats
    • Christopher TA, Lopez BL, Stillwagon JC, et al. Idoxifene causes endothelium-dependent, nitric oxide-mediated vasorelaxation in male rats. Eur J Pharmacol 2002;446:139-43
    • (2002) Eur J Pharmacol , vol.446 , pp. 139-143
    • Christopher, T.A.1    Lopez, B.L.2    Stillwagon, J.C.3
  • 44
    • 18744419819 scopus 로고    scopus 로고
    • Chronic effects of toremifene on the vasculature of menopause-induced rats
    • Gonzalez-Perez J, Crespo MJ. Chronic effects of toremifene on the vasculature of menopause-induced rats. Vascul Pharmacol 2003;40:261-8
    • (2003) Vascul Pharmacol , vol.40 , pp. 261-268
    • Gonzalez-Perez, J.1    Crespo, M.J.2
  • 45
    • 1642545158 scopus 로고    scopus 로고
    • Hyper-reactivity of cerebral arteries from ovariectomized rats: Therapeutic benefit of tamoxifen
    • Thorin E, Pham-Dang M, Clement R, Mercier I, Calderone A. Hyper-reactivity of cerebral arteries from ovariectomized rats: therapeutic benefit of tamoxifen. Br J Pharmacol 2003;140:1187-92
    • (2003) Br J Pharmacol , vol.140 , pp. 1187-1192
    • Thorin, E.1    Pham-Dang, M.2    Clement, R.3    Mercier, I.4    Calderone, A.5
  • 46
    • 12244304833 scopus 로고    scopus 로고
    • Acute vascular effects of the selective estrogen receptor modulator EM-652 (SCH 57068) in the rat mesenteric vascular bed
    • Tatchum-Talom R, Martel C, Labrie F, Marette A. Acute vascular effects of the selective estrogen receptor modulator EM-652 (SCH 57068) in the rat mesenteric vascular bed. Cardiovasc Res 2003;57:535-43
    • (2003) Cardiovasc Res , vol.57 , pp. 535-543
    • Tatchum-Talom, R.1    Martel, C.2    Labrie, F.3    Marette, A.4
  • 47
    • 0033771599 scopus 로고    scopus 로고
    • Tamoxifen acutely relaxes coronary arteries by an endothelium-, nitric oxide- and estrogen receptor-dependent mechanism
    • Figtree GA, Webb CM, Collins P. Tamoxifen acutely relaxes coronary arteries by an endothelium-, nitric oxide- and estrogen receptor-dependent mechanism. J Pharmacol Exp Ther 2000;295:519-23
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 519-523
    • Figtree, G.A.1    Webb, C.M.2    Collins, P.3
  • 48
    • 0034770441 scopus 로고    scopus 로고
    • Tamoxifen is an acute, estrogen-like, coronary vasodilator of porcine coronary arteries in vitro
    • Hutchison SJ, Chou TM, Chatterjee K, Sudhir K. Tamoxifen is an acute, estrogen-like, coronary vasodilator of porcine coronary arteries in vitro. J Cardiovasc Pharmacol 2001;38:657-65
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 657-665
    • Hutchison, S.J.1    Chou, T.M.2    Chatterjee, K.3    Sudhir, K.4
  • 50
    • 0037197781 scopus 로고    scopus 로고
    • Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production
    • Wassmann S, Laufs U, Stamenkovic D, et al. Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production. Circulation 2002;105:2083-91
    • (2002) Circulation , vol.105 , pp. 2083-2091
    • Wassmann, S.1    Laufs, U.2    Stamenkovic, D.3
  • 51
    • 0031903106 scopus 로고    scopus 로고
    • Effects of gonadal steroids and their antagonists on DNA synthesis in human vascular cells
    • Somjen D, Kohen F, Jaffe A, Amir-Zaltsman Y, Knoll E, Stern N. Effects of gonadal steroids and their antagonists on DNA synthesis in human vascular cells. Hypertension 1998;32:39-45
    • (1998) Hypertension , vol.32 , pp. 39-45
    • Somjen, D.1    Kohen, F.2    Jaffe, A.3    Amir-Zaltsman, Y.4    Knoll, E.5    Stern, N.6
  • 52
    • 0042353842 scopus 로고    scopus 로고
    • Both estrogen and raloxifene cause G1 arrest of vascular smooth muscle cells
    • Takahashi K, Ohmichi M, Yoshida M, et al. Both estrogen and raloxifene cause G1 arrest of vascular smooth muscle cells. J Endocrinol 2003;178:319-29
    • (2003) J Endocrinol , vol.178 , pp. 319-329
    • Takahashi, K.1    Ohmichi, M.2    Yoshida, M.3
  • 53
    • 0141619266 scopus 로고    scopus 로고
    • Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells
    • Mori-Abe A, Tsutsumi S, Takahashi K, et al. Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells. J Endocrinol 2003;178:417-26
    • (2003) J Endocrinol , vol.178 , pp. 417-426
    • Mori-Abe, A.1    Tsutsumi, S.2    Takahashi, K.3
  • 54
    • 0033524745 scopus 로고    scopus 로고
    • Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth
    • Dubey RK, Tyurina YY, Tyurin VA, et al. Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth. Circ Res 1999;84:229-39
    • (1999) Circ Res , vol.84 , pp. 229-239
    • Dubey, R.K.1    Tyurina, Y.Y.2    Tyurin, V.A.3
  • 55
    • 0030953982 scopus 로고    scopus 로고
    • Tamoxifen decreases cholesterol sevenfold and abolishes lipid lesion development in apolipoprotein E knockout mice
    • Reckless J, Metcalfe JC, Grainger DJ. Tamoxifen decreases cholesterol sevenfold and abolishes lipid lesion development in apolipoprotein E knockout mice. Circulation 1997;95:1542-8
    • (1997) Circulation , vol.95 , pp. 1542-1548
    • Reckless, J.1    Metcalfe, J.C.2    Grainger, D.J.3
  • 56
    • 0036191158 scopus 로고    scopus 로고
    • Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene
    • Selzman CH, Turner AS, Gaynor JS, Miller SA, Monnet E, Harken AH. Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene. Arch Surg 2002;137:333-6
    • (2002) Arch Surg , vol.137 , pp. 333-336
    • Selzman, C.H.1    Turner, A.S.2    Gaynor, J.S.3    Miller, S.A.4    Monnet, E.5    Harken, A.H.6
  • 57
    • 0030806090 scopus 로고    scopus 로고
    • Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits
    • Bjarnason NH, Haarbo J, Byrjalsen I, Kauffman RF, Christiansen C. Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits. Circulation 1997;96:1964-9
    • (1997) Circulation , vol.96 , pp. 1964-1969
    • Bjarnason, N.H.1    Haarbo, J.2    Byrjalsen, I.3    Kauffman, R.F.4    Christiansen, C.5
  • 59
    • 0035196550 scopus 로고    scopus 로고
    • Raloxifene and estrogen reduces progression of advanced atherosclerosis - a study in ovariectomized, cholesterol-fed rabbits
    • Bjarnason NH, Haarbo J, Byrjalsen I, Alexandersen P, Kauffman RF, Christiansen C. Raloxifene and estrogen reduces progression of advanced atherosclerosis - a study in ovariectomized, cholesterol-fed rabbits. Atherosclerosis 2001;154:97-102
    • (2001) Atherosclerosis , vol.154 , pp. 97-102
    • Bjarnason, N.H.1    Haarbo, J.2    Byrjalsen, I.3    Alexandersen, P.4    Kauffman, R.F.5    Christiansen, C.6
  • 60
    • 0031733090 scopus 로고    scopus 로고
    • Lack of effect of raloxifene on coronary artery atherosclerosis of postmenopausal monkeys
    • Clarkson TB, Anthony MS, Jerome CP. Lack of effect of raloxifene on coronary artery atherosclerosis of postmenopausal monkeys. J Clin Endocrinol Metab 1998;83:721-6
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 721-726
    • Clarkson, T.B.1    Anthony, M.S.2    Jerome, C.P.3
  • 61
    • 10844258492 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator idoxifene inhibits smooth muscle cell proliferation, enhances reendothelialization, and inhibits neointimal formation in vivo after vascular injury
    • Yue TL, Vickery-Clark L, Louden CS, et al. Selective estrogen receptor modulator idoxifene inhibits smooth muscle cell proliferation, enhances reendothelialization, and inhibits neointimal formation in vivo after vascular injury. Circulation 2000;102(Suppl 3):281-8
    • (2000) Circulation , vol.102 , Issue.SUPPL. 3 , pp. 281-288
    • Yue, T.L.1    Vickery-Clark, L.2    Louden, C.S.3
  • 62
    • 0030033913 scopus 로고    scopus 로고
    • Antiatherogenic effects of adjuvant antiestrogens: A randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node-positive breast cancer
    • Saarto T, Blomqvist C, Ehnholm C, Taskinen MR, Elomaa I. Antiatherogenic effects of adjuvant antiestrogens: a randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node-positive breast cancer. J Clin Oncol 1996;14:429-33
    • (1996) J Clin Oncol , vol.14 , pp. 429-433
    • Saarto, T.1    Blomqvist, C.2    Ehnholm, C.3    Taskinen, M.R.4    Elomaa, I.5
  • 63
    • 0030664688 scopus 로고    scopus 로고
    • Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women
    • Delmas PD, Bjarnason NH, Mitlak BH, et al. Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. N Engl J Med 1997;337:1641-7
    • (1997) N Engl J Med , vol.337 , pp. 1641-1647
    • Delmas, P.D.1    Bjarnason, N.H.2    Mitlak, B.H.3
  • 64
    • 2642712522 scopus 로고    scopus 로고
    • Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women
    • Walsh BW, Kuller LH, Wild RA, et al. Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women. JAMA 1998;279:1445-51
    • (1998) JAMA , vol.279 , pp. 1445-1451
    • Walsh, B.W.1    Kuller, L.H.2    Wild, R.A.3
  • 65
    • 0033729727 scopus 로고    scopus 로고
    • Serum lipid levels during and after adjuvant toremifene or tamoxifen therapy for breast cancer
    • Joensuu H, Holli K, Oksanen H, Valavaara R. Serum lipid levels during and after adjuvant toremifene or tamoxifen therapy for breast cancer. Breast Cancer Res Treat 2000;63:225-34
    • (2000) Breast Cancer Res Treat , vol.63 , pp. 225-234
    • Joensuu, H.1    Holli, K.2    Oksanen, H.3    Valavaara, R.4
  • 66
    • 0034080257 scopus 로고    scopus 로고
    • Cardiovascular effects of droloxifene, a new selective estrogen receptor modulator, in healthy postmenopausal women
    • Herrington DM, Pusser BE, Riley WA, et al. Cardiovascular effects of droloxifene, a new selective estrogen receptor modulator, in healthy postmenopausal women. Arterioscler Thromb Vasc Biol 2000;20:1606-12
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1606-1612
    • Herrington, D.M.1    Pusser, B.E.2    Riley, W.A.3
  • 67
    • 0038467378 scopus 로고    scopus 로고
    • A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkers
    • Decensi A, Robertson C, Viale G, et al. A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkers. J Natl Cancer Inst 2003;95:779-90
    • (2003) J Natl Cancer Inst , vol.95 , pp. 779-790
    • Decensi, A.1    Robertson, C.2    Viale, G.3
  • 68
    • 77957126077 scopus 로고
    • Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
    • The Writing Group for the PEPI Trial
    • The Writing Group for the PEPI Trial. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA 1995;273:199-208
    • (1995) JAMA , vol.273 , pp. 199-208
  • 69
    • 0035880662 scopus 로고    scopus 로고
    • Design and methods of the Raloxifene Use for The Heart (RUTH) study
    • Mosca L, Barrett-Connor E, Wenger NK, et al. Design and methods of the Raloxifene Use for The Heart (RUTH) study. Am J Cardiol 2001;88:392-5
    • (2001) Am J Cardiol , vol.88 , pp. 392-395
    • Mosca, L.1    Barrett-Connor, E.2    Wenger, N.K.3
  • 70
    • 11144357308 scopus 로고    scopus 로고
    • A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women
    • Reid IR, Eastell R, Fogelman I, et al. A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women. Arch Intern Med 2004;164:871-9
    • (2004) Arch Intern Med , vol.164 , pp. 871-879
    • Reid, I.R.1    Eastell, R.2    Fogelman, I.3
  • 71
    • 0031434783 scopus 로고    scopus 로고
    • Severe hypertriglyceridemia caused by tamoxifentreatment after breast cancer surgery
    • Hozumi Y, Kawano M, Miyata M. Severe hypertriglyceridemia caused by tamoxifentreatment after breast cancer surgery. Endocr J 1997;44:745-9
    • (1997) Endocr J , vol.44 , pp. 745-749
    • Hozumi, Y.1    Kawano, M.2    Miyata, M.3
  • 72
    • 0030877809 scopus 로고    scopus 로고
    • Delayed severe hypertriglyceridemia from tamoxifen
    • Kanel KT, Wolmark N, Thompson PD. Delayed severe hypertriglyceridemia from tamoxifen. N Engl J Med 1997;337:281
    • (1997) N Engl J Med , vol.337 , pp. 281
    • Kanel, K.T.1    Wolmark, N.2    Thompson, P.D.3
  • 73
    • 0035948745 scopus 로고    scopus 로고
    • Effects of raloxifene and hormone replacement therapy on markers of serum atherogenicity in healthy postmenopausal women
    • Anderson PW, Cox DA, Sashegyi A, Paul S, Silfen SL, Walsh BW. Effects of raloxifene and hormone replacement therapy on markers of serum atherogenicity in healthy postmenopausal women. Maturitas 2001;39:71-7
    • (2001) Maturitas , vol.39 , pp. 71-77
    • Anderson, P.W.1    Cox, D.A.2    Sashegyi, A.3    Paul, S.4    Silfen, S.L.5    Walsh, B.W.6
  • 74
    • 0642306447 scopus 로고    scopus 로고
    • Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women
    • Ylikorkala O, Cacciatore B, Halonen K, et al. Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women. Menopause 2003;10:440-7
    • (2003) Menopause , vol.10 , pp. 440-447
    • Ylikorkala, O.1    Cacciatore, B.2    Halonen, K.3
  • 75
    • 10044262008 scopus 로고    scopus 로고
    • HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women
    • Vogelvang TE, Mijatovic V, Kenemans P, Teerlink T, van der Mooren MJ. HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women. Fertil Steril 2004;82:1540-9
    • (2004) Fertil Steril , vol.82 , pp. 1540-1549
    • Vogelvang, T.E.1    Mijatovic, V.2    Kenemans, P.3    Teerlink, T.4    van der Mooren, M.J.5
  • 77
    • 0035572888 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma no concentrations, endothelin-1 levels, and endotheliumdependent vasodilation in postmenopausal women
    • Saitta A, Altavilla D, Cucinotta D, et al. Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma no concentrations, endothelin-1 levels, and endotheliumdependent vasodilation in postmenopausal women. Arterioscler Thromb Vasc Biol 2001;21:1512-19
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1512-1519
    • Saitta, A.1    Altavilla, D.2    Cucinotta, D.3
  • 80
    • 12244268675 scopus 로고    scopus 로고
    • Effects of raloxifene on carotid blood flow resistance and endothelium-dependent vasodilation in postmenopausal women
    • Ceresini G, Marchini L, Rebecchi I, et al. Effects of raloxifene on carotid blood flow resistance and endothelium-dependent vasodilation in postmenopausal women. Atherosclerosis 2003;167:121-7
    • (2003) Atherosclerosis , vol.167 , pp. 121-127
    • Ceresini, G.1    Marchini, L.2    Rebecchi, I.3
  • 81
    • 0041730620 scopus 로고    scopus 로고
    • Effects of raloxifene on endothelium-dependent dilation, lipoproteins, and markers of vascular function in postmenopausal women with coronary artery disease
    • Griffiths KA, Sader MA, Skilton MR, Harmer JA, Celermajer DS. Effects of raloxifene on endothelium-dependent dilation, lipoproteins, and markers of vascular function in postmenopausal women with coronary artery disease. J Am Coll Cardiol 2003;42:698-704
    • (2003) J Am Coll Cardiol , vol.42 , pp. 698-704
    • Griffiths, K.A.1    Sader, M.A.2    Skilton, M.R.3    Harmer, J.A.4    Celermajer, D.S.5
  • 82
    • 0010429412 scopus 로고    scopus 로고
    • Koh KK, Bui MN, Mincemoyer R, Cannon RO 3rd. Effects of hormone therapy on inflammatory cell adhesion molecules in postmenopausal healthy women. Am J Cardiol 1997;80:1505-7
    • Koh KK, Bui MN, Mincemoyer R, Cannon RO 3rd. Effects of hormone therapy on inflammatory cell adhesion molecules in postmenopausal healthy women. Am J Cardiol 1997;80:1505-7
  • 83
    • 0034662771 scopus 로고    scopus 로고
    • Effects of estrogen and the selective estrogen receptor modulator raloxifene on markers of inflammation in postmenopausal women
    • Blum A, Schenke WH, Hathaway L, et al. Effects of estrogen and the selective estrogen receptor modulator raloxifene on markers of inflammation in postmenopausal women. Am J Cardiol 2000;86:892-5
    • (2000) Am J Cardiol , vol.86 , pp. 892-895
    • Blum, A.1    Schenke, W.H.2    Hathaway, L.3
  • 85
    • 0033052138 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Different actions on vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells
    • Simoncini T, De Caterina R, Genazzani AR. Selective estrogen receptor modulators: different actions on vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells. J Clin Endocrinol Metab 1999;84:815-18
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 815-818
    • Simoncini, T.1    De Caterina, R.2    Genazzani, A.R.3
  • 86
    • 0034841635 scopus 로고    scopus 로고
    • Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women
    • Herrington DM, Brosnihan KB, Pusser BE, et al. Differential effects of E and droloxifene on C-reactive protein and other markers of inflammation in healthy postmenopausal women. J Clin Endocrinol Metab 2001;86:4216-22
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4216-4222
    • Herrington, D.M.1    Brosnihan, K.B.2    Pusser, B.E.3
  • 87
    • 0037016060 scopus 로고    scopus 로고
    • Influence of tamoxifen on carotid intima-media thickness in postmenopausal women
    • Simon T, Boutouyrie P, Simon JM, et al. Influence of tamoxifen on carotid intima-media thickness in postmenopausal women. Circulation 2002;106:2925-9
    • (2002) Circulation , vol.106 , pp. 2925-2929
    • Simon, T.1    Boutouyrie, P.2    Simon, J.M.3
  • 88
    • 3042815057 scopus 로고    scopus 로고
    • Tamoxifen improves endothelial function and reduces carotid intima-media thickness in postmenopausal women
    • Stamatelopoulos KS, Lekakis JP, Poulakaki NA, et al. Tamoxifen improves endothelial function and reduces carotid intima-media thickness in postmenopausal women. Am Heart J 2004;147:1093-9
    • (2004) Am Heart J , vol.147 , pp. 1093-1099
    • Stamatelopoulos, K.S.1    Lekakis, J.P.2    Poulakaki, N.A.3
  • 89
    • 0242661401 scopus 로고    scopus 로고
    • Different expression of MMPs/TIMP-1 in human atherosclerotic lesions. Relation to plaque features and vascular bed
    • Orbe J, Fernandez L, Rodriguez JA, et al. Different expression of MMPs/TIMP-1 in human atherosclerotic lesions. Relation to plaque features and vascular bed. Atherosclerosis 2003;170:269-76
    • (2003) Atherosclerosis , vol.170 , pp. 269-276
    • Orbe, J.1    Fernandez, L.2    Rodriguez, J.A.3
  • 90
    • 10044226344 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor induces MMP-9 expression: Implications for destabilization of human atherosclerotic plaques
    • Kong YZ, Yu X, Tang JJ, et al. Macrophage migration inhibitory factor induces MMP-9 expression: implications for destabilization of human atherosclerotic plaques. Atherosclerosis 2005;178:207-15
    • (2005) Atherosclerosis , vol.178 , pp. 207-215
    • Kong, Y.Z.1    Yu, X.2    Tang, J.J.3
  • 91
    • 19944384876 scopus 로고    scopus 로고
    • Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques
    • Kong YZ, Huang XR, Ouyang X, et al. Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques. Cardiovasc Res 2005;65:272-82
    • (2005) Cardiovasc Res , vol.65 , pp. 272-282
    • Kong, Y.Z.1    Huang, X.R.2    Ouyang, X.3
  • 92
    • 0034669457 scopus 로고    scopus 로고
    • Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management
    • Zanger D, Yang BK, Ardans J, et al. Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management. J Am Coll Cardiol 2000;36:1797-802
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1797-1802
    • Zanger, D.1    Yang, B.K.2    Ardans, J.3
  • 94
    • 0038644890 scopus 로고    scopus 로고
    • New markers for cardiovascular disease risk in women: Impact of endogenous estrogen status and exogenous postmenopausal hormone therapy
    • Davison S, Davis SR. New markers for cardiovascular disease risk in women: impact of endogenous estrogen status and exogenous postmenopausal hormone therapy. J Clin Endocrinol Metab 2003;88:2470-8
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2470-2478
    • Davison, S.1    Davis, S.R.2
  • 95
    • 0035099170 scopus 로고    scopus 로고
    • Generation of C-reactive protein and complement components in atherosclerotic plaques
    • Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am J Pathol 2001;158:1039-51
    • (2001) Am J Pathol , vol.158 , pp. 1039-1051
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 96
    • 7244242357 scopus 로고    scopus 로고
    • Chemokines in the pathogenesis of vascular disease
    • Charo IF, Taubman MB. Chemokines in the pathogenesis of vascular disease. Circ Res 2004;95:858-66
    • (2004) Circ Res , vol.95 , pp. 858-866
    • Charo, I.F.1    Taubman, M.B.2
  • 97
    • 11844262719 scopus 로고    scopus 로고
    • Macrophage activation in atherosclerosis: Pathogenesis and pharmacology of plaque rupture
    • Boyle JJ. Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol 2005;3:63-8
    • (2005) Curr Vasc Pharmacol , vol.3 , pp. 63-68
    • Boyle, J.J.1
  • 98
    • 0035005368 scopus 로고    scopus 로고
    • Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice
    • Elhage R, Clamens S, Besnard S, et al. Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice. Atherosclerosis 2001;156:315-20
    • (2001) Atherosclerosis , vol.156 , pp. 315-320
    • Elhage, R.1    Clamens, S.2    Besnard, S.3
  • 99
    • 0036180939 scopus 로고    scopus 로고
    • Estradiol down-regulates MCP-1 expression in human coronary artery endothelial cells
    • Seli E, Pehlivan T, Selam B, Garcia-Velasco JA, Arici A. Estradiol down-regulates MCP-1 expression in human coronary artery endothelial cells. Fertil Steril 2002;77:542-7
    • (2002) Fertil Steril , vol.77 , pp. 542-547
    • Seli, E.1    Pehlivan, T.2    Selam, B.3    Garcia-Velasco, J.A.4    Arici, A.5
  • 100
    • 0034456409 scopus 로고    scopus 로고
    • The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: A randomized, controlled trial
    • Walsh BW, Paul S, Wild RA, et al. The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled trial. J Clin Endocrinol Metab 2000;85:214-18
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 214-218
    • Walsh, B.W.1    Paul, S.2    Wild, R.A.3
  • 101
    • 0035140813 scopus 로고    scopus 로고
    • Tamoxifen and cardiac risk factors in healthy women: Suggestion of an anti-inflammatory effect
    • Cushman M, Costantino JP, Tracy RP, et al. Tamoxifen and cardiac risk factors in healthy women: suggestion of an anti-inflammatory effect. Arterioscler Thromb Vasc Biol 2001;21:255-61
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 255-261
    • Cushman, M.1    Costantino, J.P.2    Tracy, R.P.3
  • 102
    • 0035489428 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha and interleukin-6 in the effects of hormone replacement therapy and raloxifene on C-reactive protein in postmenopausal women
    • Walsh BW, Cox DA, Sashegyi A, Dean RA, Tracy RP, Anderson PW. Role of tumor necrosis factor-alpha and interleukin-6 in the effects of hormone replacement therapy and raloxifene on C-reactive protein in postmenopausal women. Am J Cardiol 2001;88:825-8
    • (2001) Am J Cardiol , vol.88 , pp. 825-828
    • Walsh, B.W.1    Cox, D.A.2    Sashegyi, A.3    Dean, R.A.4    Tracy, R.P.5    Anderson, P.W.6
  • 103
    • 10344259093 scopus 로고    scopus 로고
    • Raloxifene modulates interleukin-6 and tumor necrosis factor-alpha synthesis in vivo: Results from a pilot clinical study
    • Gianni W, Ricci A, Gazzaniga P, et al. Raloxifene modulates interleukin-6 and tumor necrosis factor-alpha synthesis in vivo: results from a pilot clinical study. J Clin Endocrinol Metab 2004;89:6097-9
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6097-6099
    • Gianni, W.1    Ricci, A.2    Gazzaniga, P.3
  • 104
    • 0032403666 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of the effects of raloxifene and conjugated equine estrogen on plasma homocysteine levels in healthy postmenopausal women
    • Mijatovic V, Netelenbos C, van der Mooren MJ, de Valk-de Roo GW, Jakobs C, Kenemans P. Randomized, double-blind, placebo-controlled study of the effects of raloxifene and conjugated equine estrogen on plasma homocysteine levels in healthy postmenopausal women. Fertil Steril 1998;70:1085-9
    • (1998) Fertil Steril , vol.70 , pp. 1085-1089
    • Mijatovic, V.1    Netelenbos, C.2    van der Mooren, M.J.3    de Valk-de Roo, G.W.4    Jakobs, C.5    Kenemans, P.6
  • 105
    • 0035089810 scopus 로고    scopus 로고
    • Randomized control study of the effects of raloxifene on serum lipids and homocysteine in older women
    • De Leo V, la Marca A, Morgante G, Lanzetta D, Setacci C, Petraglia F. Randomized control study of the effects of raloxifene on serum lipids and homocysteine in older women. Am J Obstet Gynecol 2001;184:350-3
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 350-353
    • De Leo, V.1    la Marca, A.2    Morgante, G.3    Lanzetta, D.4    Setacci, C.5    Petraglia, F.6
  • 106
    • 0037176785 scopus 로고    scopus 로고
    • A 2-year, randomized, comparative, placebo-controlled study on the effects of raloxifene on lipoprotein(a) and homocysteine
    • Smolders RG, Vogelvang TE, Mijatovic V, et al. A 2-year, randomized, comparative, placebo-controlled study on the effects of raloxifene on lipoprotein(a) and homocysteine. Maturitas 2002;41:105-14
    • (2002) Maturitas , vol.41 , pp. 105-114
    • Smolders, R.G.1    Vogelvang, T.E.2    Mijatovic, V.3
  • 107
    • 0141997686 scopus 로고    scopus 로고
    • Hormone replacement therapy and inflammation: Interactions in cardiovascular disease
    • Miller AP, Chen YF, Xing D, Feng W, Oparil S. Hormone replacement therapy and inflammation: interactions in cardiovascular disease. Hypertension 2003;42:657-63
    • (2003) Hypertension , vol.42 , pp. 657-663
    • Miller, A.P.1    Chen, Y.F.2    Xing, D.3    Feng, W.4    Oparil, S.5
  • 108
    • 0032726311 scopus 로고    scopus 로고
    • Acute coronary syndromes: Pathophysiology and preventive priorities
    • Badimon JJ, Zaman A, Helft G, Fayad Z, Fuster V. Acute coronary syndromes: pathophysiology and preventive priorities. Thromb Haemost 1999;82:997-1004
    • (1999) Thromb Haemost , vol.82 , pp. 997-1004
    • Badimon, J.J.1    Zaman, A.2    Helft, G.3    Fayad, Z.4    Fuster, V.5
  • 109
    • 0027499966 scopus 로고
    • The effect of estrogen replacement therapy on platelet aggregation and adenosine triphosphate release in postmenopausal women
    • Bar J, Tepper R, Fuchs J, Pardo J, Goldberger S, Ovadia J. The effect of estrogen replacement therapy on platelet aggregation and adenosine triphosphate release in postmenopausal women. Obstet Gynecol 1993;81:261-4
    • (1993) Obstet Gynecol , vol.81 , pp. 261-264
    • Bar, J.1    Tepper, R.2    Fuchs, J.3    Pardo, J.4    Goldberger, S.5    Ovadia, J.6
  • 110
    • 0031595187 scopus 로고    scopus 로고
    • Effect of 17beta-estradiol on inhibition of platelet aggregation in vitro is mediated by an increase in NO synthesis
    • Nakano Y, Oshima T, Matsuura H, Kajiyama G, Kambe M. Effect of 17beta-estradiol on inhibition of platelet aggregation in vitro is mediated by an increase in NO synthesis. Arterioscler Thromb Vasc Biol 1998;18:961-7
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 961-967
    • Nakano, Y.1    Oshima, T.2    Matsuura, H.3    Kajiyama, G.4    Kambe, M.5
  • 111
    • 0031951183 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on cardiovascular risk factors in postmenopausal women
    • Chen FPL, Lee N, Wang CH, Soong YK. Effects of hormone replacement therapy on cardiovascular risk factors in postmenopausal women. Fertil Steril 1998;69:267-73
    • (1998) Fertil Steril , vol.69 , pp. 267-273
    • Chen, F.P.L.1    Lee, N.2    Wang, C.H.3    Soong, Y.K.4
  • 112
    • 0033786970 scopus 로고    scopus 로고
    • Regulation of platelet aggregation and adenosine triphosphate release in vitro by 17beta-estradiol and medroxyprogesterone acetate in postmenopausal women
    • Bar J, Lahav J, Hod M, Ben-Rafael Z, Weinberger I, Brosens J. Regulation of platelet aggregation and adenosine triphosphate release in vitro by 17beta-estradiol and medroxyprogesterone acetate in postmenopausal women. Thromb Haemost 2000;84:695-700
    • (2000) Thromb Haemost , vol.84 , pp. 695-700
    • Bar, J.1    Lahav, J.2    Hod, M.3    Ben-Rafael, Z.4    Weinberger, I.5    Brosens, J.6
  • 113
    • 19244382901 scopus 로고    scopus 로고
    • The effect of hormone replacement therapy on Ca2+ mobilization and P-selectin (CD62P) expression in platelets examined under flow cytometry
    • García-Martínez MC, Labiós M, Hermenegildo C, Tarín JJ, O'Connor E, Cano A. The effect of hormone replacement therapy on Ca2+ mobilization and P-selectin (CD62P) expression in platelets examined under flow cytometry. Blood Coagul Fibrinolysis 2004;15:1-8
    • (2004) Blood Coagul Fibrinolysis , vol.15 , pp. 1-8
    • García-Martínez, M.C.1    Labiós, M.2    Hermenegildo, C.3    Tarín, J.J.4    O'Connor, E.5    Cano, A.6
  • 115
    • 18044364454 scopus 로고    scopus 로고
    • Differential effects of 17{beta}-estradiol, conjugated equine estrogen and raloxifene on mRNA expression, aggregation and secretion in platelets
    • Jayachandran M, Mukherjee R, Steinkamp T, et al. Differential effects of 17{beta}-estradiol, conjugated equine estrogen and raloxifene on mRNA expression, aggregation and secretion in platelets. Am J Physiol Heart Circ Physiol 2005;288:H2355-62
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Jayachandran, M.1    Mukherjee, R.2    Steinkamp, T.3
  • 116
    • 0028200447 scopus 로고
    • Paradoxical influence of estrogenic hormones on platelet-endothelial cell interactions
    • Miller ME, Dores GM, Thorpe SL, Akerley WL. Paradoxical influence of estrogenic hormones on platelet-endothelial cell interactions. Thromb Res 1994;74:577-94
    • (1994) Thromb Res , vol.74 , pp. 577-594
    • Miller, M.E.1    Dores, G.M.2    Thorpe, S.L.3    Akerley, W.L.4
  • 117
    • 0028909917 scopus 로고
    • Influence of hormones on platelet intracellular calcium
    • Miller ME, Thorpe SL, Dores GM. Influence of hormones on platelet intracellular calcium. Thromb Res 1995;77:515-30
    • (1995) Thromb Res , vol.77 , pp. 515-530
    • Miller, M.E.1    Thorpe, S.L.2    Dores, G.M.3
  • 118
    • 0033382707 scopus 로고    scopus 로고
    • Both raloxifene and estrogen reduce major cardiovascular risk factors in healthy postmenopausal women: A 2-year, placebo-controlled study
    • de Valk-de Roo GW, Stehouwer CD, et al. Both raloxifene and estrogen reduce major cardiovascular risk factors in healthy postmenopausal women: a 2-year, placebo-controlled study. Arterioscler Thromb Vasc Biol 1999;19:2993-3000
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2993-3000
    • de Valk-de Roo, G.W.1    Stehouwer, C.D.2
  • 119
    • 0035798788 scopus 로고    scopus 로고
    • Cardiovascular effects of tamoxifen in women with and without heart disease: Breast cancer prevention trial. National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial Investigators
    • Reis SE, Costantino JP, Wickerham DL, Tan-Chiu E, Wang J, Kavanah M. Cardiovascular effects of tamoxifen in women with and without heart disease: breast cancer prevention trial. National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial Investigators. J Natl Cancer Inst 2001;93:16-21
    • (2001) J Natl Cancer Inst , vol.93 , pp. 16-21
    • Reis, S.E.1    Costantino, J.P.2    Wickerham, D.L.3    Tan-Chiu, E.4    Wang, J.5    Kavanah, M.6
  • 120
    • 18744416833 scopus 로고    scopus 로고
    • KEEPS: The Kronos Early Estrogen Prevention Study
    • Harman SM, Brinton EA, Cedars M, et al. KEEPS: The Kronos Early Estrogen Prevention Study. Climacteric 2005;8:1-2
    • (2005) Climacteric , vol.8 , pp. 1-2
    • Harman, S.M.1    Brinton, E.A.2    Cedars, M.3
  • 121
    • 18544381541 scopus 로고    scopus 로고
    • Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis: Four-year results from a randomized clinical trial
    • Delmas PD, Ensrud KE, Adachi JD, et al. Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis: four-year results from a randomized clinical trial. J Clin Endocrinol Metab 2002;87:3609-17
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3609-3617
    • Delmas, P.D.1    Ensrud, K.E.2    Adachi, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.