-
1
-
-
0035098323
-
Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy
-
Alexandersen P, Riis BJ, Stakkestad JA, Delmas PD, Christiansen C (2001) Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy. J Clin Endocrinol Metab 86:755-760
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 755-760
-
-
Alexandersen, P.1
Riis, B.J.2
Stakkestad, J.A.3
Delmas, P.D.4
Christiansen, C.5
-
2
-
-
0032700731
-
The new selective estrogen receptor modulator MDL 103, 323 increases bone mineral density and bone strength in adult ovariectomized rats
-
Ammann P, Bourrin S, Bonjour J-P, Brunner F, Meyer J-M, Rizzoli R (1999) The new selective estrogen receptor modulator MDL 103, 323 increases bone mineral density and bone strength in adult ovariectomized rats. Osteoporos Int 10:369-376
-
(1999)
Osteoporos Int
, vol.10
, pp. 369-376
-
-
Ammann, P.1
Bourrin, S.2
Bonjour, J.-P.3
Brunner, F.4
Meyer, J.-M.5
Rizzoli, R.6
-
3
-
-
13344259303
-
Chemoprevention of mammary carcinogenesis in the rat: Combined use of raloxifene and 9-cis-retinoic acid
-
Anzano MA, Peer CW, Smith JM, Mullen LT, Shrader MW, Logsdon DL, et al. (1996) Chemoprevention of mammary carcinogenesis in the rat: combined use of raloxifene and 9-cis-retinoic acid. J Natl Cancer Inst 88:23-25
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 23-25
-
-
Anzano, M.A.1
Peer, C.W.2
Smith, J.M.3
Mullen, L.T.4
Shrader, M.W.5
Logsdon, D.L.6
-
4
-
-
0037138787
-
Raloxifene and cardiovascular events in osteoporotic postmenopausal women: Four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial
-
Barrett-Connor E, Grady D, Sashegyi A, Anderson PW, Cox DA, Hoszowski K, et al. (2002) Raloxifene and cardiovascular events in osteoporotic postmenopausal women: Four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial. J Am Med Assoc 287:847-857
-
(2002)
J Am Med Assoc
, vol.287
, pp. 847-857
-
-
Barrett-Connor, E.1
Grady, D.2
Sashegyi, A.3
Anderson, P.W.4
Cox, D.A.5
Hoszowski, K.6
-
5
-
-
0141613777
-
-
Baselga J, Llombart-Cussac A, Bellet M, Guillem-Porta V, Enas N, Krejcy K, et al. (2003) Ann Oncol 14:1383-1390
-
(2003)
Ann Oncol
, vol.14
, pp. 1383-1390
-
-
Baselga, J.1
Llombart-Cussac, A.2
Bellet, M.3
Guillem-Porta, V.4
Enas, N.5
Krejcy, K.6
-
6
-
-
0032520737
-
Clomiphene analogs with activity in vitro and in vivo against human breast cancer cells
-
Baumann RJ, Bush TL, Cross-Doersen DE, Cashman EA, Wright PS, Zwolshen JH, et al. (1998) Clomiphene analogs with activity in vitro and in vivo against human breast cancer cells. Biochem Pharmacol 55:841-851
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 841-851
-
-
Baumann, R.J.1
Bush, T.L.2
Cross-Doersen, D.E.3
Cashman, E.A.4
Wright, P.S.5
Zwolshen, J.H.6
-
7
-
-
0028167482
-
Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats
-
Black LJ, Sato M, Rowley ER, Magee DE, Bekele A, Williams DC, et al. (1994) Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats. J Clin Invest 93:63-69
-
(1994)
J Clin Invest
, vol.93
, pp. 63-69
-
-
Black, L.J.1
Sato, M.2
Rowley, E.R.3
Magee, D.E.4
Bekele, A.5
Williams, D.C.6
-
8
-
-
0036137310
-
Recovery of proximal tibia bone mineral density and strength but not cancellous bone architecture, after longterm bisphosphonate or selective estrogen receptor modulator in aged rats
-
Bourrin S, Ammann P, Bonjour J-P, Rizzoli R (2002) Recovery of proximal tibia bone mineral density and strength but not cancellous bone architecture, after longterm bisphosphonate or selective estrogen receptor modulator in aged rats. Bone 30:195-200
-
(2002)
Bone
, vol.30
, pp. 195-200
-
-
Bourrin, S.1
Ammann, P.2
Bonjour, J.-P.3
Rizzoli, R.4
-
9
-
-
0031962302
-
Tamoxifen and toremifene in breast cancer: Comparison of safety and efficacy
-
Buzdar AU, Hortobagyi GN (1998) Tamoxifen and toremifene in breast cancer: comparison of safety and efficacy. J Clin Oncol 26:348-353
-
(1998)
J Clin Oncol
, vol.26
, pp. 348-353
-
-
Buzdar, A.U.1
Hortobagyi, G.N.2
-
10
-
-
0035991549
-
Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/Pg-positive advanced breast cancer
-
Buzdar A, Hayes D, El Khoudary A, Yan S, Lonning P, Lichinitser M, et al. (2002) Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/Pg-positive advanced breast cancer. Breast Cancer Res Treat 73:161-175
-
(2002)
Breast Cancer Res Treat
, vol.73
, pp. 161-175
-
-
Buzdar, A.1
Hayes, D.2
El Khoudary, A.3
Yan, S.4
Lonning, P.5
Lichinitser, M.6
-
11
-
-
0037445127
-
Phase II, randomized, double-blind study of two dose levels of arzoxifene in patients with locally advanced or metastatic breast cancer
-
Buzdar A, O'Shaughnessy JA, Booser DJ, Pippen JE Jr, Jones SE, Munster PN, et al. (2003) Phase II, randomized, double-blind study of two dose levels of arzoxifene in patients with locally advanced or metastatic breast cancer. J Clin Oncol 21:1007-1014
-
(2003)
J Clin Oncol
, vol.21
, pp. 1007-1014
-
-
Buzdar, A.1
O'Shaughnessy, J.A.2
Booser, D.J.3
Pippen Jr., J.E.4
Jones, S.E.5
Munster, P.N.6
-
12
-
-
0035120523
-
Continued breast cancer risk reduction in postmenopausal women treated with Raloxifene: 4-year results from the MORE trial
-
Cauley JA, Norton L, Lippman ME, Eckert S, Krueger KA, Purdie DW, et al. (2001) Continued breast cancer risk reduction in postmenopausal women treated with Raloxifene: 4-year results from the MORE trial. Breast Cancer Res Treat 65:125-134
-
(2001)
Breast Cancer Res Treat
, vol.65
, pp. 125-134
-
-
Cauley, J.A.1
Norton, L.2
Lippman, M.E.3
Eckert, S.4
Krueger, K.A.5
Purdie, D.W.6
-
13
-
-
0035166970
-
Effects of a new selective estrogen receptor modulator (MDL 103, 323) on cancellous and cortical bone in ovariectomized ewes: A biochemical, histomorphometric, and densitometric study
-
Chavassieux P, Garnero P, Duboeuf F, Vergnaud P, Brunner-Ferber F, Delmas PD, et al (2001) Effects of a new selective estrogen receptor modulator (MDL 103, 323) on cancellous and cortical bone in ovariectomized ewes: a biochemical, histomorphometric, and densitometric study. J Bone Miner Res 16:89-96
-
(2001)
J Bone Miner Res
, vol.16
, pp. 89-96
-
-
Chavassieux, P.1
Garnero, P.2
Duboeuf, F.3
Vergnaud, P.4
Brunner-Ferber, F.5
Delmas, P.D.6
-
14
-
-
0033989737
-
Uterine effects of 3-year raloxifene therapy in postmenopausal women younger than age 60
-
Cohen FJ, Watts S, Shah A, Akers R, Plouffe L Jr (2000) Uterine effects of 3-year raloxifene therapy in postmenopausal women younger than age 60. Obstet Gynecol 95:104-110
-
(2000)
Obstet Gynecol
, vol.95
, pp. 104-110
-
-
Cohen, F.J.1
Watts, S.2
Shah, A.3
Akers, R.4
Plouffe Jr., L.5
-
15
-
-
0036154579
-
Multipledose, safety, pharmacokinetics and pharmacodynamics of a new selective estrogen receptor modulator, ERA-923, in healthy postmenopausal women
-
Cotreau MM, Stonis L, Dykstra KH, Gandhi T, Gutiérrez M, Xu J, et al. (2002) Multipledose, safety, pharmacokinetics and pharmacodynamics of a new selective estrogen receptor modulator, ERA-923, in healthy postmenopausal women. J Clin Pharmacol 42:157-165
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 157-165
-
-
Cotreau, M.M.1
Stonis, L.2
Dykstra, K.H.3
Gandhi, T.4
Gutiérrez, M.5
Xu, J.6
-
16
-
-
0031915352
-
Effects of LY-117018 HCl on bone remodeling and mineral density in the oophorectomized rat
-
Díaz Curiel M, Calero JA, Guerrero R, Gala J, Gazapo R, De La Piedra C (1998) Effects of LY-117018 HCl on bone remodeling and mineral density in the oophorectomized rat. Am J Obstet Gynecol 178:320-325
-
(1998)
Am J Obstet Gynecol
, vol.178
, pp. 320-325
-
-
Díaz Curiel, M.1
Calero, J.A.2
Guerrero, R.3
Gala, J.4
Gazapo, R.5
De La Piedra, C.6
-
17
-
-
0034846422
-
Effect of raloxifene on breast cancer cell Ki67 and apoptosis: A double-blind, lacebo-controlled, randomized clinical trial in postmenopausal patients
-
Dowsett M, Bundred NJ, Decensi A, Sainsbury RC, Lu Y, Hills MJ, et al. (2001) Effect of raloxifene on breast cancer cell Ki67 and apoptosis: a double-blind, lacebo-controlled, randomized clinical trial in postmenopausal patients. Can Epidemiol Biomar Prev 10:961-966
-
(2001)
Can Epidemiol Biomar Prev
, vol.10
, pp. 961-966
-
-
Dowsett, M.1
Bundred, N.J.2
Decensi, A.3
Sainsbury, R.C.4
Lu, Y.5
Hills, M.J.6
-
18
-
-
0033581212
-
Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. Results from a 3-year randomized clinical trial
-
Ettinger B, Black DM, Mitlak BH, Knickerbocker RK, Nickelsen T, Genant HK (1999) Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. Results from a 3-year randomized clinical trial. J Am Med Assoc 282:637-645.
-
(1999)
J Am Med Assoc
, vol.282
, pp. 637-645
-
-
Ettinger, B.1
Black, D.M.2
Mitlak, B.H.3
Knickerbocker, R.K.4
Nickelsen, T.5
Genant, H.K.6
-
19
-
-
84892848557
-
-
Corrections published in
-
Corrections published in J Am Med Assoc 282:2124
-
J Am Med Assoc
, vol.282
, pp. 2124
-
-
-
20
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin, et al. (1998) Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 90:1371-1388
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Redmond, C.K.4
Kavanah, M.5
Cronin6
-
21
-
-
0030176408
-
Time dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: Effects of raloxifene HCl, tamoxifen, estrogen and alendronate
-
Frolik CA, Bryant HU, Black EC, Magee DE, Chandrasekhar S (1996) Time dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: effects of raloxifene HCl, tamoxifen, estrogen and alendronate. Bone 18:621-627
-
(1996)
Bone
, vol.18
, pp. 621-627
-
-
Frolik, C.A.1
Bryant, H.U.2
Black, E.C.3
Magee, D.E.4
Chandrasekhar, S.5
-
23
-
-
0036738995
-
Adverse events that are associated with the selective estrogen receptor modulator levormeloxifene in an aborted phase III osteoporosis treatment study
-
Goldstein SR, Nanavati N (2002) Adverse events that are associated with the selective estrogen receptor modulator levormeloxifene in an aborted phase III osteoporosis treatment study. Am J Obstet Gynecol 187:521-527
-
(2002)
Am J Obstet Gynecol
, vol.187
, pp. 521-527
-
-
Goldstein, S.R.1
Nanavati, N.2
-
24
-
-
0034929234
-
Raloxifene effect on frequency of surgery for pelvic floor relaxation
-
Goldstein SR, Neven P, Zhou L, Taylot YL, Ciaccia AV, Plouffle L (2001) Raloxifene effect on frequency of surgery for pelvic floor relaxation. Obstet Gynecol 98:91-96
-
(2001)
Obstet Gynecol
, vol.98
, pp. 91-96
-
-
Goldstein, S.R.1
Neven, P.2
Zhou, L.3
Taylot, Y.L.4
Ciaccia, A.V.5
Plouffle, L.6
-
25
-
-
0034787326
-
A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl- ethoxy)-benzyl]-1H-indol-5-ol hydroclorhide (ERA-923), inhibits the growth of tamoxifen-sensitive and-resistant tumors and is devoid of uterotropic effects in mice and rats
-
Greenbeger LM, Annable T, Collins KI, Komm BS, Lyttle CR, Miller CP, et al. (2001) A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin- 1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydroclorhide (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats. Clin Cancer Res 7:3166-3177
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3166-3177
-
-
Greenbeger, L.M.1
Annable, T.2
Collins, K.I.3
Komm, B.S.4
Lyttle, C.R.5
Miller, C.P.6
-
26
-
-
0037052731
-
Comparison of the effects of EM-652(SCH570068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast cancer in nude
-
Gutman M, Couillard S, Roy J, Labrie F, Candas B, Labrie C (2002) Comparison of the effects of EM-652(SCH570068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast cancer in nude. Int J Cancer 99:273-278
-
(2002)
Int J Cancer
, vol.99
, pp. 273-278
-
-
Gutman, M.1
Couillard, S.2
Roy, J.3
Labrie, F.4
Candas, B.5
Labrie, C.6
-
27
-
-
0035683624
-
Effect of selective estrogen receptor modulators on reproductive tissues other than endometrium
-
Hendrix SL, McNeeley SG (2001) Effect of selective estrogen receptor modulators on reproductive tissues other than endometrium. Ann NY Acad Sci 949:243-250
-
(2001)
Ann NY Acad Sci
, vol.949
, pp. 243-250
-
-
Hendrix, S.L.1
McNeeley, S.G.2
-
28
-
-
20144383817
-
Differential effects of estrogen and raloxifene on mRNA and matrix metalloproteinase 2 (MMP2) activity in the rat uterus
-
Epub ahead of print, DOI:10.1095/biolreprod.104.034595
-
Helvering LM, Adrian MD, Geiser AG, Estrem ST, Wei T, Huang S, et al. (2004) Differential effects of estrogen and raloxifene on mRNA and matrix metalloproteinase 2 (MMP2) activity in the rat uterus. Biol Reprod [Epub ahead of print]. DOI:10.1095/biolreprod.104.034595
-
(2004)
Biol Reprod
-
-
Helvering, L.M.1
Adrian, M.D.2
Geiser, A.G.3
Estrem, S.T.4
Wei, T.5
Huang, S.6
-
29
-
-
0032547326
-
Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women
-
Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, et al. (1998) Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. J Am Med Assoc 280:605-613
-
(1998)
J Am Med Assoc
, vol.280
, pp. 605-613
-
-
Hulley, S.1
Grady, D.2
Bush, T.3
Furberg, C.4
Herrington, D.5
Riggs, B.6
-
30
-
-
0033304703
-
Tamoxifen, raloxifene, and the prevention of breast cancer
-
Jordan VC, Morrow M (1999) Tamoxifen, raloxifene, and the prevention of breast cancer. Endocr Rev 20:253-78
-
(1999)
Endocr Rev
, vol.20
, pp. 253-278
-
-
Jordan, V.C.1
Morrow, M.2
-
31
-
-
0031013929
-
Comparative effects of droloxifene, tamoxifen, and estrogen on bone, serum cholesterol, and uterine histology in the ovariectomized rat model
-
Ke HZ, Chen HK, Simmons HA, Crawford DT, Pirie CM, Chidsey-Frink KL et al. (1997) Comparative effects of droloxifene, tamoxifen, and estrogen on bone, serum cholesterol, and uterine histology in the ovariectomized rat model. Bone 20:31-39
-
(1997)
Bone
, vol.20
, pp. 31-39
-
-
Ke, H.Z.1
Chen, H.K.2
Simmons, H.A.3
Crawford, D.T.4
Pirie, C.M.5
Chidsey-Frink, K.L.6
-
32
-
-
0001236520
-
Effects of CP-336, 156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat models
-
Ke HZ, Paralkar VM, Grasser WA, Crawford DT, Qi H, Simmons H, et al. (1998) Effects of CP-336, 156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat models. Endocrinology 139:2068-2076
-
(1998)
Endocrinology
, vol.139
, pp. 2068-2076
-
-
Ke, H.Z.1
Paralkar, V.M.2
Grasser, W.A.3
Crawford, D.T.4
Qi, H.5
Simmons, H.6
-
33
-
-
0035082747
-
Lasofoxifene (CP-336, 156) protects against the age-related changes in bone mass, bone strength, and total serum cholesterol in intact aged male rats
-
Ke HZ, Qi H, Chidsey-Frink KL, Crawford DT, Thompson DD (2001) Lasofoxifene (CP-336, 156) protects against the age-related changes in bone mass, bone strength, and total serum cholesterol in intact aged male rats. J Bone Miner Res 16:765-773
-
(2001)
J Bone Miner Res
, vol.16
, pp. 765-773
-
-
Ke, H.Z.1
Qi, H.2
Chidsey-Frink, K.L.3
Crawford, D.T.4
Thompson, D.D.5
-
34
-
-
0034457008
-
Lasofoxifene (CP-336, 156), a selective estrogen receptor modulator, prevents bone loss induced by aging and orchidectomy in the adult rat
-
Ke HZ, Qi H, Crawford DT, Chidsey-Frink KL, Simmons HA, Thompson DD (2000) Lasofoxifene (CP-336, 156), a selective estrogen receptor modulator, prevents bone loss induced by aging and orchidectomy in the adult rat. Endocrinology 141:1338-1344
-
(2000)
Endocrinology
, vol.141
, pp. 1338-1344
-
-
Ke, H.Z.1
Qi, H.2
Crawford, D.T.3
Chidsey-Frink, K.L.4
Simmons, H.A.5
Thompson, D.D.6
-
35
-
-
1642489155
-
Long-term treatment of lasofoxifene preserves bone mass and bone strength and does not adversely affect the uterus in ovariectomized rats
-
Ke HZ, Foley GL, Simmons HA, Shen V, Thompson DD (2004) Long-term treatment of lasofoxifene preserves bone mass and bone strength and does not adversely affect the uterus in ovariectomized rats. Endocrinology 145:1996-2005
-
(2004)
Endocrinology
, vol.145
, pp. 1996-2005
-
-
Ke, H.Z.1
Foley, G.L.2
Simmons, H.A.3
Shen, V.4
Thompson, D.D.5
-
36
-
-
0035686794
-
Developing SERM: Stringent preclinical selection criteria leading to an acceptable candidate (WAY-140424) for clinical evaluation
-
Komm BS, Lyttle CR (2001) Developing SERM: stringent preclinical selection criteria leading to an acceptable candidate (WAY-140424) for clinical evaluation. Ann NY Acad Sci 949:317-326
-
(2001)
Ann NY Acad Sci
, vol.949
, pp. 317-326
-
-
Komm, B.S.1
Lyttle, C.R.2
-
37
-
-
0033051859
-
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and the endometrium
-
Labrie F, Labrie C, Bélanger A, Simard J, Gauthier S, Luu-The V, et al. (1999) EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and the endometrium. J Steroid Biochem Mol Biol 69:51-84
-
(1999)
J Steroid Biochem Mol Biol
, vol.69
, pp. 51-84
-
-
Labrie, F.1
Labrie, C.2
Bélanger, A.3
Simard, J.4
Gauthier, S.5
Luu-The, V.6
-
38
-
-
1542503724
-
Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer
-
Labrie F, Champagne P, Labrie C, Roy J, Laverdière J, Provencher L, et al. (2004) Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer. J Clin Oncol 22:864-871
-
(2004)
J Clin Oncol
, vol.22
, pp. 864-871
-
-
Labrie, F.1
Champagne, P.2
Labrie, C.3
Roy, J.4
Laverdière, J.5
Provencher, L.6
-
40
-
-
0031799147
-
The preventive and interventional effects of raloxifene analog (LY117018 HCl) on osteopenia in ovariectomized rats
-
Li X, Takahashi M, Kushida K, Inoue T (1998) The preventive and interventional effects of raloxifene analog (LY117018 HCl) on osteopenia in ovariectomized rats. J Bone Miner Res 13:1005-1010
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1005-1010
-
-
Li, X.1
Takahashi, M.2
Kushida, K.3
Inoue, T.4
-
41
-
-
0026585852
-
Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer
-
Love RR, Mazess RB, Barden HS, Epstein S, Newcomb PA, Jordan VC, et al. (1992) Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer. N Engl J Med 326:852-856
-
(1992)
N Engl J Med
, vol.326
, pp. 852-856
-
-
Love, R.R.1
Mazess, R.B.2
Barden, H.S.3
Epstein, S.4
Newcomb, P.A.5
Jordan, V.C.6
-
42
-
-
0036896165
-
Long-term dosing of arzoxifene lowers cholesterol, reduces bone turnover, and preserves bone quality in ovariectomized rats
-
Ma YL, Bryant HU, Zeng Q, Palkowitz A, Jee W S S, Turner CH, et al. (2002) Long-term dosing of arzoxifene lowers cholesterol, reduces bone turnover, and preserves bone quality in ovariectomized rats. J Bone Miner Res 17:2256-2264
-
(2002)
J Bone Miner Res
, vol.17
, pp. 2256-2264
-
-
Ma, Y.L.1
Bryant, H.U.2
Zeng, Q.3
Palkowitz, A.4
Jee, W.S.S.5
Turner, C.H.6
-
43
-
-
0030695441
-
Toremifene in postmenopausal breast cancer: Efficacy, safety and cost
-
Maenpaa JU, Ala-Fossi SL (1997) Toremifene in postmenopausal breast cancer: efficacy, safety and cost. Drugs Aging 11:261-270
-
(1997)
Drugs Aging
, vol.11
, pp. 261-270
-
-
Maenpaa, J.U.1
Ala-Fossi, S.L.2
-
44
-
-
0035811739
-
Postmenopausal hormone-replacement therapy
-
Manson JE, Martin KA (2001) Postmenopausal hormone-replacement therapy. N Engl J Med 345:34-40
-
(2001)
N Engl J Med
, vol.345
, pp. 34-40
-
-
Manson, J.E.1
Martin, K.A.2
-
45
-
-
10644283864
-
Continuing Outcomes Relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
-
Martino S, Cauley JA, Barrett-Connor E, Powles TJ, Mershon J, Disch D, et al. (2004) Continuing Outcomes Relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J Natl Cancer Inst 96:1751-1761
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1751-1761
-
-
Martino, S.1
Cauley, J.A.2
Barrett-Connor, E.3
Powles, T.J.4
Mershon, J.5
Disch, D.6
-
46
-
-
0032722761
-
Effects of tamoxifen and toremifene on urinary excretion of pyridinoline and deoxypyridinoline and bone density in postmenopausal women with breast cancer
-
Marttunen MB, Hietanen P, Titinen A, Roth H-J, Viinikka L, Ylikorkala O (1999) Effects of tamoxifen and toremifene on urinary excretion of pyridinoline and deoxypyridinoline and bone density in postmenopausal women with breast cancer. Calcif Tissue Int 65:365-368
-
(1999)
Calcif Tissue Int
, vol.65
, pp. 365-368
-
-
Marttunen, M.B.1
Hietanen, P.2
Titinen, A.3
Roth, H.-J.4
Viinikka, L.5
Ylikorkala, O.6
-
47
-
-
17144400542
-
Comparison of lasofoxifene and raloxifene for the prevention of bone loss in postmenopausal women
-
McClung M, Omizo M, Weiss S, Moffett A, Bolognese M, Civitelli R, et al. (2004a) Comparison of lasofoxifene and raloxifene for the prevention of bone loss in postmenopausal women. J Bone Miner Res 19 (Suppl 1): F424
-
(2004)
J Bone Miner Res
, vol.19
, Issue.SUPPL. 1
-
-
McClung, M.1
Omizo, M.2
Weiss, S.3
Moffett, A.4
Bolognese, M.5
Civitelli, R.6
-
48
-
-
17144379874
-
-
McClung M, Portman D, Emkey R, McKenny J, Ettinger M, Somayaji V, et al. (2004b) Comparison of theextraskeletal effects of lasofoxifene and raloxifene. 19 (Suppl 1): SA423
-
(2004)
Comparison of Theextraskeletal Effects of Lasofoxifene and Raloxifene
, vol.19
, Issue.SUPPL. 1
-
-
McClung, M.1
Portman, D.2
Emkey, R.3
McKenny, J.4
Ettinger, M.5
Somayaji, V.6
-
49
-
-
0037244752
-
Advances in the science of estrogen receptor modulation
-
Meegan MJ, Lloyd DG (2003) Advances in the science of estrogen receptor modulation. Curr Med Chem 10:181-210
-
(2003)
Curr Med Chem
, vol.10
, pp. 181-210
-
-
Meegan, M.J.1
Lloyd, D.G.2
-
50
-
-
0035942513
-
Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens
-
Miller CP, Collini MD, Tran BD, Harris HA, Kharode YP, Marzolf JT, et al. (2001) Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens. J Med Chem 44:1654-1657
-
(2001)
J Med Chem
, vol.44
, pp. 1654-1657
-
-
Miller, C.P.1
Collini, M.D.2
Tran, B.D.3
Harris, H.A.4
Kharode, Y.P.5
Marzolf, J.T.6
-
51
-
-
17144396489
-
Lasofoxifene, a next generation SERM, is effective in preventing loss of BMD and reducing LDL-C in postmenopausal women
-
Moffett AH, Ettinger M, Bolognese M, Weiss S, Somayaji V, Brunell R, et al. (2004) Lasofoxifene, a next generation SERM, is effective in preventing loss of BMD and reducing LDL-C in postmenopausal women. J Bone Miner Res 19 (Suppl 1): F426
-
(2004)
J Bone Miner Res
, vol.19
, Issue.SUPPL. 1
-
-
Moffett, A.H.1
Ettinger, M.2
Bolognese, M.3
Weiss, S.4
Somayaji, V.5
Brunell, R.6
-
52
-
-
0035048519
-
Raloxifene affects brain activation patterns in postmenopausal women during visual encoding
-
Neele SJ, Rombouts SA, Bierlaagh MA, Barkhof F, Scheltens P, Netelenbos JC (2001) Raloxifene affects brain activation patterns in postmenopausal women during visual encoding. J Clin Endocrinol Metab 86:1422-1424
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1422-1424
-
-
Neele, S.J.1
Rombouts, S.A.2
Bierlaagh, M.A.3
Barkhof, F.4
Scheltens, P.5
Netelenbos, J.C.6
-
53
-
-
0031725563
-
Idoxifene: A novel selective estrogen receptor modulator prevents bone loss and lowers cholesterol levels in ovariectomized rats and decreases uterine weight in intact rats
-
Nuttall ME, Bradbeer JN, Stroup GB, Nadeau DP, Hoffman SJ, Zhao H, et al. (1998) Idoxifene: a novel selective estrogen receptor modulator prevents bone loss and lowers cholesterol levels in ovariectomized rats and decreases uterine weight in intact rats. Endocrinology 139:5224-5234
-
(1998)
Endocrinology
, vol.139
, pp. 5224-5234
-
-
Nuttall, M.E.1
Bradbeer, J.N.2
Stroup, G.B.3
Nadeau, D.P.4
Hoffman, S.J.5
Zhao, H.6
-
54
-
-
0032556191
-
Effects of the antiestrogens tamoxifen, toremifene, and ICI 182, 780 on endometrial cancer growth
-
O'Regan RM, Cisneros GM, England GM, MacGregor JI, Muenzner HD, Assikis VJ, et al. (1998) Effects of the antiestrogens tamoxifen, toremifene, and ICI 182, 780 on endometrial cancer growth. J Natl Cancer Inst 90:1552-1555
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1552-1555
-
-
O'Regan, R.M.1
Cisneros, G.M.2
England, G.M.3
MacGregor, J.I.4
Muenzner, H.D.5
Assikis, V.J.6
-
55
-
-
17744368482
-
Selective estrogen effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact ovariectomized rats
-
Qu Q, Zheng H, Dahllund J, Laine A, Cockcroft N, Peng Z, et al. (2000) Selective estrogen effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact ovariectomized rats. Endocrinology 141:809-820
-
(2000)
Endocrinology
, vol.141
, pp. 809-820
-
-
Qu, Q.1
Zheng, H.2
Dahllund, J.3
Laine, A.4
Cockcroft, N.5
Peng, Z.6
-
56
-
-
0000327721
-
TSE-424, a novel tissue selective estrogen, reduces biochemical indices of bone metabolissm in a dose-related fashion
-
Ronkin S, Clarke L, Boudes P, Constantine G (2001) TSE-424, a novel tissue selective estrogen, reduces biochemical indices of bone metabolissm in a dose-related fashion. J Bone Miner Res 16 (Suppl): S413
-
(2001)
J Bone Miner Res
, vol.16
, Issue.SUPPL.
-
-
Ronkin, S.1
Clarke, L.2
Boudes, P.3
Constantine, G.4
-
57
-
-
0642367765
-
Effects of ospemifene, a novel SERM, on hormones, genitl tract, climateric symptoms, and quality of life in postmenopausal women: A double-blind, randomized trial
-
Rutanen EM, Heikkinen J, Halonen K, Komi J, Lammintausta R, Ylikorkala O (2003) Effects of ospemifene, a novel SERM, on hormones, genitl tract, climateric symptoms, and quality of life in postmenopausal women: a double-blind, randomized trial. Menopause 10:440-447
-
(2003)
Menopause
, vol.10
, pp. 440-447
-
-
Rutanen, E.M.1
Heikkinen, J.2
Halonen, K.3
Komi, J.4
Lammintausta, R.5
Ylikorkala, O.6
-
58
-
-
85047679337
-
LY353381 HCl: An improved benzothiophe analog with bone efficacy complementary to parathyroid hormone-(1-34)
-
Sato M, Zeng GQ, Rowley E, Turner CH (1998) LY353381 HCl: an improved benzothiophe analog with bone efficacy complementary to parathyroid hormone-(1-34). Endocrinology 139:4642-4651
-
(1998)
Endocrinology
, vol.139
, pp. 4642-4651
-
-
Sato, M.1
Zeng, G.Q.2
Rowley, E.3
Turner, C.H.4
-
59
-
-
6344293770
-
Selective estrogen receptor modulators prevent neointima formation after vascular injury
-
Savolainen-Peltonen H, Luoto NM, Kangas L, Häyry P (2004) Selective estrogen receptor modulators prevent neointima formation after vascular injury. Mol Cell Endocrinol 227:9-20
-
(2004)
Mol Cell Endocrinol
, vol.227
, pp. 9-20
-
-
Savolainen-Peltonen, H.1
Luoto, N.M.2
Kangas, L.3
Häyry, P.4
-
60
-
-
0035963494
-
Side effects of adjuvant treatment of breast cancer
-
Shapiro CL, Recht A (2001) Side effects of adjuvant treatment of breast cancer. N Engl J Med 344:1997-2008
-
(2001)
N Engl J Med
, vol.344
, pp. 1997-2008
-
-
Shapiro, C.L.1
Recht, A.2
-
61
-
-
0033983181
-
Estrogen agonistic/antagonistic effects of miproxifene phosphate (TAT-59)
-
Shibata J, Toko T, Saito H, Fujioka A, Sato K, Hashimoto A, et al. (2000) Estrogen agonistic/antagonistic effects of miproxifene phosphate (TAT-59). Cancer Chemother Pharmacol 35:133-141
-
(2000)
Cancer Chemother Pharmacol
, vol.35
, pp. 133-141
-
-
Shibata, J.1
Toko, T.2
Saito, H.3
Fujioka, A.4
Sato, K.5
Hashimoto, A.6
-
62
-
-
2942755831
-
Conjugated equibe estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women. Women's Health Initiative Memory Study
-
Shumaker SA, Legault C, Kuller L, Rapp SR, Thal L, Lane DS, et al. (2004) Conjugated equibe estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women. Women's Health Initiative Memory Study. J Am Med Assoc 291:2947-2958
-
(2004)
J Am Med Assoc
, vol.291
, pp. 2947-2958
-
-
Shumaker, S.A.1
Legault, C.2
Kuller, L.3
Rapp, S.R.4
Thal, L.5
Lane, D.S.6
-
63
-
-
0034971572
-
Centchroman, a selective estrogen receptor modulator, as a contraceptive and for the management of hormone-related clinical disorders
-
Singh MM (2001) Centchroman, a selective estrogen receptor modulator, as a contraceptive and for the management of hormone-related clinical disorders. Med Res Rev 21:302-347
-
(2001)
Med Res Rev
, vol.21
, pp. 302-347
-
-
Singh, M.M.1
-
64
-
-
0038210242
-
Aromatase inhibitors in breast cancer
-
Smith IE, Dowsett M (2003) Aromatase inhibitors in breast cancer. N Engl J Med 348:2431-2442
-
(2003)
N Engl J Med
, vol.348
, pp. 2431-2442
-
-
Smith, I.E.1
Dowsett, M.2
-
66
-
-
10744220231
-
Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat
-
Sutherland KM, Brady H, Gayo-Fung LM, Leisten J, Lipps SG, McKie JA, et al. (2003) Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat. Calcif Tissue Int 72:710-716
-
(2003)
Calcif Tissue Int
, vol.72
, pp. 710-716
-
-
Sutherland, K.M.1
Brady, H.2
Gayo-Fung, L.M.3
Leisten, J.4
Lipps, S.G.5
McKie, J.A.6
-
68
-
-
0025361621
-
TAT-59, a new triphenylethylene derivative with antitumor activity against hormone-dependent tumors
-
Toko T, Sugimoto Y, Matsuo K, Yamasaki R, Takeda S, Wierzba K, et al. (1990) TAT-59, a new triphenylethylene derivative with antitumor activity against hormone-dependent tumors. Eur J Cancer 26:397-404
-
(1990)
Eur J Cancer
, vol.26
, pp. 397-404
-
-
Toko, T.1
Sugimoto, Y.2
Matsuo, K.3
Yamasaki, R.4
Takeda, S.5
Wierzba, K.6
-
69
-
-
0036347450
-
The study of tamoxifen and raloxifene: Preliminary enrollment data from a randomized breast cancer risk reduction trial
-
Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Wolmark N (2002) The study of tamoxifen and raloxifene: preliminary enrollment data from a randomized breast cancer risk reduction trial. Clin Breast Cancer 3:153-159
-
(2002)
Clin Breast Cancer
, vol.3
, pp. 153-159
-
-
Vogel, V.G.1
Costantino, J.P.2
Wickerham, D.L.3
Cronin, W.M.4
Wolmark, N.5
-
70
-
-
0036890079
-
Baseline characteristics of participants in the raloxifene use for the heart (RUTH) trial
-
Wenger NK, Barrett-Connor E, Collins P, Grady D, Kornitzer M, Mosca L, et al. (2002) Baseline characteristics of participants in the raloxifene use for the heart (RUTH) trial. Am J Cardiol 90:1204-1210
-
(2002)
Am J Cardiol
, vol.90
, pp. 1204-1210
-
-
Wenger, N.K.1
Barrett-Connor, E.2
Collins, P.3
Grady, D.4
Kornitzer, M.5
Mosca, L.6
-
71
-
-
0022638821
-
A phase I/II investigation of trioxifene mesylate in advanced breast cancer. Clinical and endocrinologic effects
-
Witte RS, Pruitt B, Tormey DC, Moss S, Rose DP, Falkson G, et al. (1986) A phase I/II investigation of trioxifene mesylate in advanced breast cancer. Clinical and endocrinologic effects. Cancer 57:34-39
-
(1986)
Cancer
, vol.57
, pp. 34-39
-
-
Witte, R.S.1
Pruitt, B.2
Tormey, D.C.3
Moss, S.4
Rose, D.P.5
Falkson, G.6
-
72
-
-
0036778134
-
Tamoxifen: An update on current data and where it can now be used
-
discussion S33-5
-
Wickerham L (2002) Tamoxifen: an update on current data and where it can now be used. Breast Cancer Res Treat 75 (Suppl 1): S7-12; discussion S33-5
-
(2002)
Breast Cancer Res Treat
, vol.75
, Issue.SUPPL. 1
-
-
Wickerham, L.1
-
73
-
-
0030741983
-
Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone
-
Willson TM, Norris JD, Wagner BL, Asplin I, Baer P, Brown HR, et al. (1997) Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology 138:3901-3911
-
(1997)
Endocrinology
, vol.138
, pp. 3901-3911
-
-
Willson, T.M.1
Norris, J.D.2
Wagner, B.L.3
Asplin, I.4
Baer, P.5
Brown, H.R.6
-
74
-
-
1842867053
-
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. The Women's Health Initiative randomized controlled trial
-
Women's Health Initiative Steering Committee
-
Women's Health Initiative Steering Committee (2004) Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. The Women's Health Initiative randomized controlled trial. J Am Med Assoc 291:1701-1712
-
(2004)
J Am Med Assoc
, vol.291
, pp. 1701-1712
-
-
-
75
-
-
0037125379
-
Risks and benefits ofestrogen plus progestin inhealthy postmenopausal women
-
Writing Group for the Women's Health Initiative Investigators
-
Writing Group for the Women's Health Initiative Investigators (2002) Risks and benefits ofestrogen plus progestin inhealthy postmenopausal women. J Am Med Assoc 288:321-333
-
(2002)
J Am Med Assoc
, vol.288
, pp. 321-333
-
-
-
76
-
-
0035912147
-
Cognitive function in postmenopausal women treated with raloxifene
-
Yaffe K, Krueger K, Sarkar S, Grady D, Barrett-Connor E, Cox DA, et al. (2001) Cognitive function in postmenopausal women treated with raloxifene. N Engl J Med 344:1207-1213
-
(2001)
N Engl J Med
, vol.344
, pp. 1207-1213
-
-
Yaffe, K.1
Krueger, K.2
Sarkar, S.3
Grady, D.4
Barrett-Connor, E.5
Cox, D.A.6
|