The kinetics of inhibition of rat recombinant heteromeric α1β glycine receptors by the low-affinity antagonist SR-95531

Journal of Physiology

Volumn 580, Issue 1, 2007, Pages 171-179

  Beato, Marco ^a   Burzomato, Valeria ^a   Sivilotti, Lucia G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; GLYCINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ANTAGONIST; RECOMBINANT RECEPTOR; ALPHA1BETA GLYCINE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE CURRENT; NEUROTRANSMISSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE; BINDING KINETICS; CELL MEMBRANE POTENTIAL; CONCENTRATION (PARAMETERS); DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG UNBINDING RATE; GLYCINE RECEPTOR BLOCKING; HEK293 CELL LINE; PATCH CLAMP TECHNIQUE; RECEPTOR BLOCKING;

ANIMALS; CELL LINE; ELECTROPHYSIOLOGY; GLYCINE; GLYCINE AGENTS; HUMANS; KINETICS; MODELS, STATISTICAL; PATCH-CLAMP TECHNIQUES; PYRIDAZINES; RATS; RECEPTORS, GLYCINE; RECOMBINANT PROTEINS; SYNAPSES;

EID: 33947541832     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.126888     Document Type: Article

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