Androgen Regulation of Prostate Morphoregulatory Gene Expression: Fgf10-dependent and -independent pathways

Endocrinology

Volumn 148, Issue 4, 2007, Pages 1697-1706

  Pu, Yongbing ^a   Huang, Liwei ^a   Birch, Lynn ^a   Prins, Gail S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANDROGEN; BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR RECEPTOR 2; HOMEODOMAIN PROTEIN; HOX PROTEIN; HYDROXYFLUTAMIDE; PD 173074; PEPTIDES AND PROTEINS; PROTEIN HOXB13; PROTEIN NKX3.1; PROTEIN PATCHED; RECEPTOR BLOCKING AGENT; SONIC HEDGEHOG PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG; WNT5A PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; EPITHELIUM CELL; GENE EXPRESSION; GENE REPRESSION; MALE; MORPHOLOGY; NEWBORN; NONHUMAN; ORGAN CULTURE; PARACRINE SIGNALING; PRIORITY JOURNAL; PROSTATE VENTRAL LOBE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; UPREGULATION; VALIDATION STUDY;

ANIMALS; FEMALE; FIBROBLAST GROWTH FACTOR 10; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MODELS, BIOLOGICAL; MORPHOGENESIS; ORGAN CULTURE TECHNIQUES; PREGNANCY; PROSTATE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TESTOSTERONE;

EID: 33947517159     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1113     Document Type: Article

References (50)

1. George FW, Peterson KG 1988 5α-Dihydrotestosterone formation is necessary for embryogenesis of the rat prostate. Endocrinology 122:1159-1164
2. Siiteri PK, Wilson JD 1974 Testosterone formation and metabolism during male sexual differentiation in the human embryo. J Clin Endocrinal Metab 38:113-125
3. Marker PC, Donjacour AA, Dahiya R, Cunha GR 2003 Hormonal, cellular, and molecular control of prostatic development. Dev Biol 253:165-174
4. McIntyre BS, Barlow NJ, Foster PM 2001 Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues. Toxicol Sci 62:236-249
5. Takeda H, Lasnitzki I, Mizunto T 1986 Analysis of prostatic bud induction by brief androgen treatment in the fetal rat urogenital sinus. J Endocrinol 110:467-470
6. Cunha GR, Donjacour AA, Cooke PS, Mee S, Bigsby RM, Higgins SJ, Sugimura Y 1987 The endocrinology and developmental biology of the prostate. Endo Rev 8:338-363
7. Donjacour AA, Cunha GR 1993 Assessment of prostatic protein secretion in tissue recombinants made of urogenital sinus mesenchyme and urothelium from normal or androgen-insensitive mice. Endocrinology 132:2342-2350
8. Prins GS, Birch L 1995 The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocrinology 136:1303-1314
9. Yan G, Fukabori Y, Nikolropoulos S, Wang F, McKeehan W 1992 Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin. Mol Endocrinol 6:2123-2128
10. Lu W, Luo Y, Kan M, McKeehan WL 1999 Fibroblast growth factor-10: a second candidate stromal to epithelial cell andromedin in prostate. J Biol Chem 274:12827-12834
11. Thomson AA 2001 Role of androgens and fibroblast growth factors in prostatic development. Reproduction 121:187-195
12. Thomson AA, Cunha GR 1999 Prostatic growth and development are regulated by FGF10. Development 126:3693-3701
13. Podlasek CA, Barnett DH, Clemens JQ, Bak PM, Bushman W 1999 Prostate development requires sonic hedgehog expressed by the urogenital sinus epithelium. Dev Biol 209:28-39
14. Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W 2001 Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol 232:301-314
15. Grishina IB, Kinm SY, Ferrara C, Makarenkova HP, Walden PD 2005 BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol 288:334-347
16. Pu Y, Huang L, Prins GS 2004 Sonic hedgehog-patched-gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching. Dev Biol 273:257-275
17. Huang L, Pu Y, Alam S, Birch L, Prins GS 2005 The role of Fgf10 signaling in branching morphogenesis and gene expression in the rat prostate gland: lobe-specific suppression by neonatal estrogens. Dev Biol 278:396-414
18. Prins GS, Huang L, Birch L, Pu Y 2006 The role of estrogens in normal and abnormal development of the prostate gland. Annal NY Acad Sci 1089:1-13
19. Prins GS, Birch L, Habermann H, Chang WY, Tebeau C, Putz O, Bieberich C 2001 Influence of neonatal estrogens on rat prostate development. Reprod Fertil Dev 13:241-252
20. Huang L, Pu Y, Alam S, Birch L, Prins GS 2004 Estrogenic regulation of signaling pathways and homeobox genes during rat prostate development. J Andrology 25:330-337
21. Corbier P, Edwards D, Roffi J 1992 The neonatal testosterone surge: a comparative study. Arch Internat Physiol Biochim Biophys 100:127-131
22. Prins GS, Birch L, Couse JF, Choi I, Katzenellenbogen B, Korach KS 2001 Estrogen imprinting of the developing prostate gland in mediated through stromal estrogen receptor α: studies with αERKO and βERKO mice. Canc Res 61:6089-6097
23. Wang Y, Hayward SW, Cao M, Thayer K, Cunha GR 2001 Cell differentiation lineage in the prostate. Differentiation 68:270-279
24. Prescott J, Blok L, Tindall D 1998 Isolation and androgen regulation of the human homeobox cDNA, NKX3.1. Prostate 35:71-80
25. Huang L, Pu Y, Birch L, Belmonte J, Prins GS, Wnt5a is required for prostate morphogenesis. Program of the American Society of Andrology (ASA) 31st Annual Conference, Chicago, IL, April 2006 (Abstract 115)
26. Wilson JD 1996 Role of dihydrotestosterone in androgen action. Prostate 6(Suppl):88-92
27. Bruchovsky N, Wilson J 1968 The conversion of testosterone to 5α-androstan-17β-ol-3-one by rat prostate in vivo and in vitro. J Biochem 243:2012-2021
28. Ellem SJ, Schmitt JF, Pedersen JS, Frydenberg M, Risbridger GP 2004 Local aromatase expression in human prostate is altered in malignancy. J Clin Endocrinol Metab 89:2431-2441
29. Prins GS, Birch L 1997 Neonatal estrogen exposure up-regulates estrogen receptor expression in the developing and adult rat prostate lobes. Endocrinology 138:1801-1809
30. Prins GS, Marmer M, Woodham C, Chang WY, Kuiper G, Gustafsson JA, Birch L 1998 Estrogen receptor-β messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats. Endocrinology 139:874-883
31. Donjacour AA, Thomson AA, Cunha G 2003 FGF-10 plays an essential role in the growth of the fetal prostate. Dev Biol 261:39-54
32. Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W 2002 Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol 249:349-366
33. Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM 2004 Roles for hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol 267:387-398
34. Doles J, Cook C, Shi X, Valosky J, Lipinski R, Bushman W 2006 Functional compensation in hedgehog signaling during mouse prostate development. Dev Biol 295:13-25
35. Sreenath T, Orosz A, Fujita K, Bieberich CJ 1999 Androgen-independent expression of hoxb-13 in the mouse prostate. Prostate 41:203-207
36. Economides KD, Capecchi MR 2003 Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development 130:2061-2069
37. Bieberich CJ, Fujita K, He WW, Jay G 1996 Prostate-specific and androgen-dependent expression of a novel homeobox gene. J Biol Chem 271:31779-31782
38. Hosohata K, Li P, Hosohata Y, Qin J, Roeder RG, Wang Z 2003 Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription. Mol Cell Biol 23:7019-7029
39. Thomas R, Anderson W, Raman V, Reddi H 1998 Androgen-dependent gene expression of bone morphogenetic protein 7 in mouse prostate. Prostate 37: 236-245
40. Crews CM, Alessandrini A, Erikson RL 1992 Erks: their fifteen minutes has arrived. Cell Growth Differ 3:135-142
41. Risbud MV, Di Martino A, Guttapalli A, Seghatoleslami R, Denaro V, Vaccaro AR, Albert TJ, Shapiro IM 2006 Toward an optimum system for intervertebral disc organ culture: TGF-β3 enhances nucleus pulposus and anulus fibrosus survival and function through modulation of TGF-β-R expression and ERK signaling. Spine 31:884-890
42. Ozaki K, Kadomoto R, Asato K, Tanimura S, Itoh N, Kohno M 2001 ERK pathway positively regulates the expression of Sprouty genes. Biochem Biophys Res Commun 285:1084-1088
43. Li C, Xiao J, Hormi K, Borok Z, Minoo P 2002 Wnt5a participates in distal lung morphogenesis. Dev Biol 248:68-81
44. Li C, Hu L, Xiao J, Chen H, Li J, Bellusci S, Delanghe S, Minoo P 2005 Wnt5a regulates Shh and Fgf10 signaling during lung development. Dev Biol 287:86-97
45. Shain SA, Boesel RW 1977 Aging-associated diminished rat prostate androgen receptor content concurrent with decreased androgen dependence. Mech Aging Dev 6:219-232
46. Witorsch RJ 1982 Regional variations in the testicular dependence of prolactin binding and its possible relationship to castration-induced involution in rat prostate gland. Prostate 3:459-473
47. Lee C 1981 Physiology of castration-induced regression in rat prostate. In: The prostatic cell: structure and function. Vol. 145-159. New York: Alan R. Liss, Inc.
48. Prins GS, Birch L, Greene GL 1991 Androgen receptor localization in different cell types of the adult rat prostate. Endocrinology 129:3187-3199
49. Prins GS 1989 Differential regulation of androgen receptors in the separate rat prostate lobes: androgen independent expression in the lateral lobe. J Steroid Biochem 33:319-326
50. Prins GS, Woodham C 1995 Autologous regulation of androgen receptor mRNA in the separate lobes of the rat prostate gland. Biol Reprod 53:609-619