A mutation in the mod subunit of EcoP15I restriction enzyme converts the DNA methyltransferase to a site-specific endonuclease

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 3520-3530

  Bist, Pradeep ^a   Madhusoodanan, Urulangodi Kunhiraman ^a   Rao, Desirazu N ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; METHIONINE; METHYLTRANSFERASE; RECOGNITION SEQUENCES;

AMINO ACIDS; CATALYST ACTIVITY; DNA SEQUENCES; MAGNESIUM; POSITIVE IONS;

ENZYME KINETICS;

DNA METHYLTRANSFERASE; ENDONUCLEASE; METHIONINE; PROLINE; RESTRICTION ENDONUCLEASE; BACTERIAL DNA; DNA MODIFICATION METHYLASE ECOP15I; ENDODEOXYRIBONUCLEASE ECOP15I; ESCHERICHIA COLI PROTEIN; MAGNESIUM; PROTEIN SUBUNIT; SITE SPECIFIC DNA METHYLTRANSFERASE (ADENINE SPECIFIC); TYPE III SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBUNIT; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; BIOSYNTHESIS; CHEMISTRY; DNA SUPERCOILING; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN BINDING;

AMINO ACID SEQUENCE; DEOXYRIBONUCLEASES, TYPE III SITE-SPECIFIC; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DNA, SUPERHELICAL; ESCHERICHIA COLI PROTEINS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN SUBUNITS; SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC);

EID: 33947512392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603250200     Document Type: Article

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