Inhibition of lipopolysaccharide-induced prostaglandin E2 production and inflammation by the Na+/H+ exchanger inhibitors

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 1, 2007, Pages 345-352

  Kamachi, Fumitaka ^a   Hyun, Seung Ban ^a   Hirasawa, Noriyasu ^a   Ohuchi, Kazuo ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b YASUDA WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIAMINO 6 CHLORO N (DIAMINOMETHYLIDENE)PYRAZINE 2 CARBOXAMIDE HYDROCHLORIDE; 5 (N ETHYL N ISOPROPYL) AMILORIDE; 5 (N,N DIMETHYL) AMILORIDE; AMILORIDE; AMILORIDE DERIVATIVE; ARACHIDONIC ACID; CYCLOOXYGENASE 2; I KAPPA B ALPHA; INDOMETACIN; LIPOPOLYSACCHARIDE; MEMBRANE PHOSPHOLIPID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; PROTEIN INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ISOTOPE LABELING; LEUKOCYTE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTON SODIUM EXCHANGE;

AMILORIDE; ANIMALS; ARACHIDONIC ACID; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; I-KAPPA B PROTEINS; INDOMETHACIN; INFLAMMATION; LEUKOCYTES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM-HYDROGEN ANTIPORTER;

EID: 33947407556     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.116251     Document Type: Article

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