Prostaglandin E2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells

Journal of Leukocyte Biology

Volumn 74, Issue 5, 2003, Pages 868-879

  Jing, Huie ^a   Vassiliou, Evros ^a   Ganea, Doina ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Bone marrow derived dendritic cells; Chemokines; Inflammation; Lipid mediators

Indexed keywords

ANTIINFLAMMATORY AGENT; CHEMOKINE; LIGAND; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; PEPTIDOGLYCAN; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; CELL ACTIVATION; CELL COUNT; CELL POPULATION; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFECT; DRUG MECHANISM; INFLAMMATION; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PERITONEAL CAVITY; PERITONEAL FLUID; PERITONEUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; DENDRITIC CELLS; DINOPROSTONE; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED STRAINS; POLYMERASE CHAIN REACTION; RECEPTORS, CHEMOKINE;

ANIMALIA;

EID: 0347991981     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0303116     Document Type: Conference Paper

References (42)

1. Banchereau, J., Steinman, R. M. (1998) The dendritic cell and the control of immunity. Nature 392, 245-252.
2. Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y. J., Pulendran, B., Palucka, K. (2000) Immunobiology of dendritic cells. Annu. Rev. Immunol. 18, 767-811.
3. Cella, M., Lanzavecchia, A., Scheidegger, D., Palmer-Lehmann, K., Lane, P., Albert, G. (1996) Ligation of Cd40 on dendritic cells triggers the production of high levels of IL-12 and enhance T cell stimulatory capacity. J. Exp. Med. 184, 747-752.
4. Verhasselt, V., Buelens, C., Willem, F., De Groot, D., Goldman, M. (1997) Bacterial lipopolysachharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells. J. Immunol, 158, 2919-2925.
5. Sallusto, F., Palermo, B., Lenig, D., Miettinen, M., Matikainen, S., Julkunen, I., Forster, R., Burgtahler, R., Lipp, M., Lanzavacchia, A. (1999) Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur. J. Immunol. 29, 1617-1625.
6. Cella, M., Engering, A., Pinet, V., Pieters, J., Lanzavecchia, A. (1997) Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782-787.
7. Rescigno, M., Citterio, S., Thery, C., Rittig, M., Medaglini, D., Pozzi, G., Amigorena, S., Ricciardi-Castagnoli, P. (1998) Bacteria induces neobiosynthesis, stabilization, and surface expression of functional class 1 molecules on mouse dendritic cells. Proc. Natl. Acad. Sci. USA 95, 5229-5234.
8. Sallusto, F., Scherli, P., Loetscher, P., Schaniel, C., Lenig, D., Mackay, C. R., Qin, S., Lanzavecchia, A. (1998) Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol. 28, 2760-2769.
9. Sozzani, S., Altavena, P., D'Amico, G., Luini, W., Bianchi, G., Kataura, M., Imai, T., Yoshie, O., Bonecchi, R., Mantovani, A. (1998) Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties. J. Immunol. 161, 1083-1086.
10. Steinman, R. M., Pack, M., Inaba, K. (1997) Dendritic cells in the T cell areas of lymphoid organs. Immunol. Rev. 156, 25-37.
11. Randolph, G. J. (2001) Dendritic cell migration to lymph nodes: cytokines, chemokines and lipid mediators. Semin. Immunol. 13, 267-274.
12. Ingulli, E., Ulman, D. R., Lucido, M. M., Jenkins, M. K. (2002) In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen. J. Immunol. 169, 2247-2252.
13. Underhill, D., Ozinsky, A. (2002) Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14, 103-110.
14. Huang, Q., Liu, D., Majewski, P., Schulte, L. C., Korn, J. M., Young, R. A., Lander, E. S., Hacohen, N. (2001) The plasticity of dendritic cell responses to pathogens and their components, Science 294, 870-875.
15. O'Neill, A. J. (2002) Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal? Trends Immunol. 23, 296-300.
16. Hanada, T., Yoshimura, A. (2002) Regulation of cytokine signaling and inflammation. Cytokine Growth Factor Rev. 13, 413-421.
17. Amsterdam A., Tajima, K., Sasson, R. (2002) Cell-specific regulation of apoptosis by glucocorticoids: implication to their anti-inflammatory action. Biochem. Pharmacol. 64, 843-850.
18. Ganea, D., Delgado, M. (2002) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) as modulators of both innate and adaptive immunity. Crit. Rev. Oral Biol. Med. 13, 229-237.
19. Tilley, S. I., Coffman, T. M., Koller, B. H. (2001) Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. J. Clin. Invest. 108, 15-23.
20. Harris, S. G., Padilla, J., Koumas, L., Ray, D., Phipps, R. P. (2002) Prostaglandins as modulators of immunity. Trends Immunol. 23, 144-150.
21. Needleman, P., Turk, J., Jakschik, B., Morrison, A., Lefkowitz, J. (1986) Arachidonic acid metabolism. Annu. Rev. Biochem. 55, 69-102.
22. Kudela, P., Schwarczova, Z., Sedlak, J., Bizik, J. (2001) Conditioned medium from HeLa cells enhances motility of human monocyte-derived dendritic cells but abrogates their maturation and endocytic activity. Neoplasma 48, 382-388.
23. Zelle-Rieser, C., Ramoner, R., Artner-Dworzak, E., Casari, A., Bartsch, G., Thurnher, M. (2002) Human monocyte-derived dendritic cells are deficient in prostaglandin E2 production. FEBS Lett. 511, 123-126.
24. Betz, M., Fox, B. (1991) Prostaglandin E2 inhibits production of Th1 lymphokines, but not of Th2 lymphokines. J. Immunol. 146, 108-113.
25. Katamura, K., Shintaku, N., Yamauchi, Y., Fukui, T., Ohshima, Y., Mayumi, M., Furusho, K. (1995) Prostaglandin E2 at priming of naïve CD4+ T cells inhibits acquisition of ability to produce IFN-gamma and IL-2, but not IL-4 and IL-5. J. Immunol. 155, 4604-4612.
26. Kalinski, P., Hilkens, C. M., Snijders, A., Snijdewint, F. G., Kapsenberg, M. L. (1997) Dendritic cells obtained from peripheral blood precursors in the presence of PGE2 promote. TH2 responses. Adv. Exp. Med. Biol. 417, 363-367.
27. Harizi, H., Juzan, M., Grosset, C., Rashedi, M., Gualde, N. (2001) Dendritic cells issued in vitro from bone marrow produce PGE2 that contributes to the immunomodulation induced by antigen-presenting cells. Cell. Immunol. 209, 19-28.
28. Kuroda, E., Sugiura, T., Okada, K., Zeki, K., Yamashita, U. (2001) Prostaglandin E2 up-regulates macrophage-derived chemokine production but suppresses IFN-inducible protein-10 production by APC. J. Immunol. 166, 1650-1658.
29. Janabi, N., Hau, I., Tardieu, M. (1999) Negative feedback between prostaglandins and alpha- and beta-chemokine synthesis in human microglial cells and astrocytes. J. Immunol. 162, 1701-1706.
30. Takayama, K., Garcia-Cardena, G., Sukhova, G. K., Comander, J., Gimbronn, M. A., Jr., Libby, P. (2002) Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor. J. Biol. Chem. 277, 44147-44154.
31. Lutz, M. B., Kukutsch, N., Ogilvie, A. L., Rossner, S., Koch, F., Romani, N., Schuler, G. (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223, 77-92.
32. Narumiya, S., Sugimoto, Y., Ushikubi, F. (1999) Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79, 1193-1226.
33. Nataraj, C., Thomas, D. W., Tilley, S. T., Nguyen, M.-T., Mannon, R., Koller, B. H., Coffman, M. (2001) Receptors for prostaglandin E2 that regulate cellular responses in the mouse. J. Clin. Invest. 108, 1229-1235.
34. Scandella, E., Men, Y., Gillessen, S., Forster, R., Groettrup, M. (2002) Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 100, 1354-1361.
35. Fennekohl, A., Sugimoto, Y., Segi, E., Maruyama, T., Ischikawa, A., Puschel, G. P. (2002) Contribution of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor tn the inhibition by PGE2 of the LPS-induced TNFα-formation in Kupffer cells from EP2- and EP4-receptor-deficient mice. Pivotal role for the EP4-receptor in wild type Kupffer cell. J. Hematol. 36, 328-334.
36. Triantafilou, M., Triantafilou, K. (2002) Lipopolysaccharide recognition: CD14, TLRs, and the LPS-activation cluster. Trends Immunol. 23, 301-304.
37. Re, F., Strominger, J. L. (2001) Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J. Biol. Chem. 276, 37692-37699.
38. Delgado, M., Ganea, D. (2001) Inhibition of endotoxin-induced macrophage chemokine production by vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide in vitro and in vivo. J. Immunol. 167, 966-975.
39. Delgado, M., Jonakait, C. M., Ganea, D. (2002) Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit chemokine production in activated microglia. Glia 39, 148-161.
40. Fujino, H., West, K. A., Regan, J. W. (2002) Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J. Biol. Chem. 277, 2614-2619.
41. Harizi, H., Juzan, M., Pitard, V., Moreau, J.-F., Gualde, N. (2002) Cyclooxygenase-2-issues prostaglandin E2 enhances the production of endogenous IL-10, which down-regulates dendritic cell functions. J. Immunol. 168, 2255-2263.
42. Jozefowski, S., Bobek, M., Marcinkiewicz, J. (2003) Exogenous but not endogenous prostanoids regulate cytokine secretion from murine bone marrow dendritic cells: EP2, DP, and IP, but not EP1, EP3, and FP prostanoid receptors are involved. Int. Immunopharmacol. 3, 865-878.