Genetic dissection of neural circuit anatomy underlying feeding behavior in Drosophila: Distinct classes of hugin-expressing neurons

Journal of Comparative Neurology

Volumn 502, Issue 5, 2007, Pages 848-856

  Bader, Rüdiger ^a   Colomb, Julien ^b   Pankratz, Bettina ^a   Schröck, Anne ^a   Stocker, Reinhard F ^b   Pankratz, Michael J ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

Axon connectivity; Gustation; Interneuron morphology; Neuropeptide; Taste center

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CLONE; CONTROLLED STUDY; DROSOPHILA; FEEDING BEHAVIOR; GENE; GENE EXPRESSION; GENE LOCATION; GENETIC ANALYSIS; GROWTH; HUGIN GENE; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BEHAVIOR, ANIMAL; DROSOPHILA; DROSOPHILA PROTEINS; FEEDING BEHAVIOR; GANGLIA, INVERTEBRATE; GREEN FLUORESCENT PROTEINS; NERVE NET; NEURITES; NEURONS; NEUROPEPTIDES;

EID: 33947403922     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.21342     Document Type: Article

References (24)

1. Amrein H, Thorne N. 2005. Gustatory perception and behavior in Drosophila melanogaster. Curr Biol 15:R673-R684.
2. Brighton PJ, Szekeres PG, Willars GB. 2004. Neuromedin U and its receptors: Structure, function, and physiological roles. Pharmacol Rev 56:231-248.
3. Broberger C. 2005. Brain regulation of food intake and appetite: molecules and networks. J Intern Med 258:301-327.
4. Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, Hafen E. 2001. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr Biol 11:213-221.
5. Colomb J, Grillenzoni N, Ramaekers A, Stocker RF. 2007. Architecture of the primary taste center of Drosophila melanogaster larvae. J Comp Neurol 502:834-847.
6. Hanada R, Teranishi H, Pearson JT, Kurokawa M, Hosoda H, Fukushima N, Rukue Y, Serine R, Fujihara H, Ueta Y, Ikawa M, Okabe M, Murakami N, Shirai M, Yoshimatsu H, Kangawa K, Kojima M. 2004. Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat Med 10:1067-1073.
7. Hirth F, Loop T, Egger B, Miller DF, Kaufman TC, Reichert H. 2001. Functional equivalence of Hox gene products in the specification of the tritocerebrum during embryonic brain development of Drosophila. Development 23:4781-4788.
8. Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Willisams DL, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hrenluk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q. 2000. Identification of receptors for neuromedin U and its role in feeding. Nature 406:70-74.
9. Hummel T, Krukkert K, Roos J, Davis G, Klambt C. 2000. Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron 26:357-370.
10. Koushika SP, Lisbin MJ, White K. 1996. ELAV, a Drosophila neuron-specific protein, mediates the generation of an alternatively spliced neural protein isoform. Curr Biol 6:1634-1641.
11. Lisbin MJ, Qiu J, White K. 2001. The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA. Genes Dev 15:2546-2561.
12. Melcher C, Pankratz MJ. 2005. Candidate gustatory interneurons modulating feeding behavior in the Drosophila brain. PLoS Biol 3:e305.
13. Melcher C, Bader R, Walther S, Simakov O, Pankratz MJ. 2006. Neuromedin U and its putative Drosophila homolog hugin. PLoS Biol 4:e68.
14. Meng X, Wahlström G, Immonen T, Komer M, Tirronen M, Predel R, Kalkkinen N, Heino T, Sariola H, Roos C. 2002. The Drosophila hugin gene codes for myostimulatory and ecdysis-modifying neuropeptides. Mech Dev 117:5-13.
15. Ramaekers A, Magnenat E, Marin EC, Gendre N, Jefferies GS, Luo, L, Stocker RF. 2005. Glomerular maps without cellular redundancy at successive levels of the Drosophila larval olfactory circuit. Curr Biol 15:982-992.
16. Rulifson EJ, Kim SK, Nusse R. 2002. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 296:1118-1120.
17. Scott K. 2005. Taste recognition: food for thought. Neuron 48:455-464.
18. Siegmund T, Korge G. 2001. Innervation of the ring gland of Drosophila. J Comp Neurol 431:481-491.
19. Stocker RF. 1994. The organization of the chemosensory system in Drosophila melanogaster: a review. Cell Tissue Res 275:3-26.
20. Takagawa K, Salvaterra P. 1996. Analysis of choline acetyltransferase protein in temperature sensitive mutant flies using newly generated monoclonal antibody. Neurosci Res 24:237-243.
21. Wagh DA, Rasse TM, Asan E, Hofbauer A, Schwenkert I, Durrbeck H, Buchner S, Dabauvalle MC, Schmidt M, Qin G, Wichmann C, Kittel R, Sigrist SJ, Buchner E. 2006. Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila. Neuron 49:833-844.
22. Whiteland JL, Nicholls SM, Shimeld C, Easty DL, Williams NA, Hill TJ. 1995. Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J Histochem Cytochem 43:313-320.
23. Wong AM, Wang JW, Axel R. 2002. Spatial representation of the glomerular map in the Drosophila protocerebrum. Cell 109:229-241.
24. Zhang Y, Proenca R, Maffei M, Barone M, Friedman JM. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432.