Effects of various pesticides on human 5α-reductase activity in prostate and LNCaP cells

Toxicology in Vitro

Volumn 21, Issue 3, 2007, Pages 502-508

  Lo, Susan ^a   King, Isabella ^a   Alléra, Axel ^a   Klingmüller, Dietrich ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

5 Reductase inhibitors; Endocrine disruptors; Human androgen metabolism; Human prostate cancer cell line LNCaP; Prostate tissue; Steroid

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; ANDROGEN; ANTIANDROGEN; DIBUTYLTIN; DIURON; ENDOCRINE DISRUPTOR; EPIANDROSTERONE; FENARIMOL; FINASTERIDE; LINURON; METHYLTESTOSTERONE; MONOBUTYLTIN; ORGANOTIN COMPOUND; PESTICIDE; PROCHLORAZ; SEX HORMONE; STEROID 5ALPHA REDUCTASE; TRIBUTYLTIN; TRIPHENYLTIN; UNCLASSIFIED DRUG; VINCLOZOLIN;

ARTICLE; CELL STRAIN LNCAP; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; MALE; SCREENING; SENSITIVITY AND SPECIFICITY; TISSUE HOMOGENATE; VIRILIZATION;

CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; PESTICIDES; PROSTATE; PROSTATIC NEOPLASMS; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 33947361935     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.10.016     Document Type: Article

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